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公开(公告)号:EP3407915A1
公开(公告)日:2018-12-05
申请号:EP17744768.7
申请日:2017-01-24
申请人: President and Fellows of Harvard College , Children's Medical Center Corporation , McCarroll, Steven A. , Sekar, Aswin , Carroll, Michael C. , Stevens, Beth
CPC分类号: A61K45/00 , A61K48/005 , C07K14/005 , C07K14/472 , C12N2740/10022 , G01N33/6896 , G01N2800/302
摘要: The invention provides methods of treating schizophrenia in a subject, including for example, administering to the subject an agent that inhibits expression or activity of a C4A polynucleotide or polypeptide. The invention also provides methods of identifying a subject having or at risk of developing schizophrenia involving measuring or detecting an alteration in the level, copy number, and/or sequence of complement component C4A or complement component C4B relative to a reference.
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2.
公开(公告)号:EP1973619A4
公开(公告)日:2010-03-31
申请号:EP06844629
申请日:2006-11-29
申请人: CARROLL MICHAEL M
发明人: CARROLL MICHAEL M
IPC分类号: A63K1/00
CPC分类号: A63K1/00
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3.
公开(公告)号:EP1973619A2
公开(公告)日:2008-10-01
申请号:EP06844629.3
申请日:2006-11-29
申请人: Carroll, Michael M.
发明人: Carroll, Michael M.
IPC分类号: A63K1/00
CPC分类号: A63K1/00
摘要: The present invention is directed to a system and method for conducting a more fair race around an oval track by having runners in each lane run equal arc angles. Such a configuration eliminates the disproportionate effect of centrifugal force on competitors running in different lanes. Embodiments of the invention provide for the addition of a straight section to a standard oval track extending from a curved section perpendicular to the existing straightaway section. Runners in each lane start at staggered locations on the straight section. The staggered starting locations are chosen such that each runner travels an equal distance from the starting location to a common finish line. A single straight section may be employed to conduct races covering the entire length and half the length of the oval track or two straight sections may be employed to allow finishes for both races at a common finish line.
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公开(公告)号:EP2389143A2
公开(公告)日:2011-11-30
申请号:EP10733971.5
申请日:2010-01-25
申请人: Carroll, Michael F.
发明人: Carroll, Michael F.
CPC分类号: A61F5/3723
摘要: A system comprising a combination of orthopedic traction devices for limiting abduction of the arm and preventing impingement of the user's shoulder. The devices include a nighttime ipsilateral shoulder traction device with removable leg and wrist cuffs, an elastic connecting strap connecting the cuffs to apply impingement-reducing traction to the shoulder joint; and a daytime centrifugal exercise device with a weighted member rotated by a handle using the ipsilateral arm. The invention also includes a method for using the two devices in combination, and a series of exercises for the centrifugal exercise device that specifically complement the nighttime impingement reduction of the traction device. In the preferred form, the traction device includes removable leg and wrist cuffs secured to the lower leg and wrist, respectively, and a one-handed quick release mechanism that allows the user to release the cuffed arm with the cuffed hand.
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公开(公告)号:EP1461402A1
公开(公告)日:2004-09-29
申请号:EP02771912.9
申请日:2002-11-08
IPC分类号: C10L1/10
CPC分类号: C10L10/00 , B01J13/0026 , C10L1/10 , C10L1/1208 , C10L1/1225 , C10L1/1233 , C10L1/1241 , C10L1/125 , C10L1/1258 , C10L1/1266 , C10L1/1275 , C10L1/1608 , C10L1/1814 , C10L1/1824 , C10L1/1826 , C10L1/1852 , C10L1/1857 , C10L1/207 , C10L1/2608 , C10L1/301 , C10L1/305 , C10L3/003 , C10L10/02 , C10L10/04
摘要: A method of improving the combustion of a fuel by adding a catalyst or combustion enhancer at an extremely low concentration, preferably in the range of 1 part catalyst per 200 million parts fuel to 1 part catalyst per 6 trillion parts fuel. The catalyst or combustion enhancer may be selected from a wide range of soluble compounds. The method may comprise the steps of an initial mixing of the catalyst or enhancer with a suitable solvent and then subsequent dilution steps using solvents or fuel. Suitable solvents include water, MTBE, methylketone, methyisobutylketone, butanol, isopropyl alcohol and other hydrophilic/oleophilic compounds.
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公开(公告)号:EP1461402A4
公开(公告)日:2006-07-12
申请号:EP02771912
申请日:2002-11-08
IPC分类号: C10L1/12 , B01J13/00 , C10L1/10 , C10L1/16 , C10L1/18 , C10L1/20 , C10L1/26 , C10L1/30 , C10L3/00 , C10L10/00 , C10L10/02 , C10L1/02 , C10L1/32 , C10L9/10 , C10M125/00 , C10M159/18
CPC分类号: C10L10/00 , B01J13/0026 , C10L1/10 , C10L1/1208 , C10L1/1225 , C10L1/1233 , C10L1/1241 , C10L1/125 , C10L1/1258 , C10L1/1266 , C10L1/1275 , C10L1/1608 , C10L1/1814 , C10L1/1824 , C10L1/1826 , C10L1/1852 , C10L1/1857 , C10L1/207 , C10L1/2608 , C10L1/301 , C10L1/305 , C10L3/003 , C10L10/02 , C10L10/04
摘要: A method of improving the combustion of a fuel by adding a catalyst or combustion enhancer at an extremely low concentration, preferably in the range of 1 part catalyst per 200 million parts fuel to 1 part catalyst per 6 trillion parts fuel. The catalyst or combustion enhancer may be selected from a wide range of soluble compounds. The method may comprise the steps of an initial mixing of the catalyst or enhancer with a suitable solvent and then subsequent dilution steps using solvents or fuel. Suitable solvents include water, MTBE, methylketone, methyisobutylketone, butanol, isopropyl alcohol and other hydrophilic/oleophilic compounds.
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