公开(公告)号：EP0681182B1

公开(公告)日：2000-04-12

申请号：EP95303003.8

申请日：1995-05-02

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen

IPC分类号： G01N30/00 ,  G01N33/00

CPC分类号： G01N33/0016 ,  G01N30/00 ,  G01N30/08 ,  G01N30/40 ,  G01N30/68 ,  G01N33/004 ,  G01N2030/121 ,  G01N2030/123 ,  G01N2030/383 ,  G01N2030/402 ,  Y10T436/214 ,  Y10T436/218 ,  Y10T436/25375 ,  Y10T436/255

公开(公告)号：EP0654667A1

公开(公告)日：1995-05-24

申请号：EP94306243.0

申请日：1994-08-24

申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN ,  CHROMATOFAST ,  HORIBA, LTD.

发明人： Sacks, Richard Douglas ,  Peters, Anita Jo ,  Klemp, Mark Allen ,  Holmes, Edward Jeffrey

IPC分类号： G01N30/46 ,  G01N30/40

CPC分类号： G01N30/461 ,  G01N30/40 ,  G01N2030/025 ,  G01N2030/121 ,  G01N2030/383 ,  G01N2030/402 ,  G01N2030/085

摘要： A gas chromatography system having a column comprising a precolumn and an analytical and also having a source of backflush pressure applied at the intersection of the precolumn and the analytical column. The split column arrangement enables the backflushing of high boiling point components while enabling the simultaneous analysis of lower boiling point components located in the analytical column upon the application of backflush pressure. This greatly reduces the cycle time of a chromatography system as it is unnecessary to backflush the much more slowly eluting, high boiling point components through the entire length of column and there is no need to delay backflushing until completion of analysis of the components of interest. In this manner, backflushing occurs simultaneously with analysis for a first reduction of cycle time, and the high boiling point components are backflushed through a reduced length of column for a second reduction of cycle time of the chromatography system. A thermal focusing chamber enables the trapping of the sample at the sample tube end closest to the precolumn enabling a much more concentrated sample which yields much broader peaks in the chromatogram.

摘要翻译： 一种气相色谱系统，其具有包括预柱和分析物的柱，并且还具有在预柱和分析柱的交叉点处施加反吹压力的源。 分离柱装置能够反冲洗高沸点组分，同时在施加反冲压力的同时分析位于分析柱中的低沸点组分。 这大大降低了色谱系统的循环时间，因为在整个柱的长度上不需要反冲洗更多的缓慢洗脱的高沸点组分，并且不需要延迟反吹，直到目标组分的分析完成。 以这种方式，在分析循环时间的第一次减少的同时进行反冲洗，并且将高沸点组分通过柱的减少长度反冲洗，从而色谱系统的循环时间的第二次降低。 热聚焦室使得能够在最靠近预柱的样品管端捕获样品，从而可以获得更浓缩的样品，在色谱图中产生更宽的峰。

公开(公告)号：EP0661537B1

公开(公告)日：1999-12-22

申请号：EP94306176.2

申请日：1994-08-22

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen ,  Peters, Anita Jo

IPC分类号： G01N30/12 ,  G01N30/40

CPC分类号： G01N30/12 ,  G01N30/40 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/123 ,  G01N2030/128 ,  G01N2030/3046 ,  G01N2030/383 ,  G01N2030/623 ,  G01N2030/3076 ,  G01N2030/3023

公开(公告)号：EP0682249A1

公开(公告)日：1995-11-15

申请号：EP95302637.4

申请日：1995-04-20

申请人： CHROMATOFAST

发明人： Klemp, Mark A.

IPC分类号： G01N30/46

CPC分类号： G01N30/463 ,  G01N30/468 ,  G01N2030/025 ,  G01N2030/383

摘要： Gas chromatography systems which provide for high speed separation of polar compounds of interest from samples which also include non-polar compounds. Efficient separation is achieved through the use of a tandem series connected combination of analytical columns, one of which having a polar stationary phase material and another having a non-polar stationary phase material. In two embodiments of the invention the order of the analytical columns is reversed. Fluid flow conduits, valves and vents are provided in a manner which eliminates mechanical valves in a sample stream.

摘要翻译： 气相色谱系统能够从样品中高速分离目标极性化合物，样品中也包括非极性化合物。 通过使用分析柱的串联串联组合实现有效分离，其中一个分析柱具有极性固定相材料，另一个具有非极性固定相材料。 在本发明的两个实施例中，分析柱的顺序是相反的。 流体流动导管，阀门和排气口以消除样品流中的机械阀的方式提供。

公开(公告)号：EP0588505A2

公开(公告)日：1994-03-23

申请号：EP93306552.6

申请日：1993-08-19

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen

IPC分类号： G01N33/00 ,  G01N30/00 ,  G01N27/62

CPC分类号： G01N33/0016 ,  G01N30/00 ,  G01N30/08 ,  G01N30/40 ,  G01N30/68 ,  G01N2030/121 ,  G01N2030/123 ,  G01N2030/383 ,  G01N2030/402

摘要： An analytical system for measuring the concentration of non-methane organic gases within a test sample including methane and non-methane component groups. The system incorporates a trap in the form of a porous layer open tubular (PLOT) column which the sample mixture is directed through and which traps the NMOG group through adsorption. The methane group passes through the trap and is vented to atmosphere or evaluated using a detector. After trapping of the NMOG group, the flow direction through the column is reversed and the column temperature is increased to desorb the NMOG group which is evaluated using a detector such as a flame ionization detector (FID).

公开(公告)号：EP0681182A1

公开(公告)日：1995-11-08

申请号：EP95303003.8

申请日：1995-05-02

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen

IPC分类号： G01N30/00 ,  G01N33/00

CPC分类号： G01N33/0016 ,  G01N30/00 ,  G01N30/08 ,  G01N30/40 ,  G01N30/68 ,  G01N33/004 ,  G01N2030/121 ,  G01N2030/123 ,  G01N2030/383 ,  G01N2030/402 ,  Y10T436/214 ,  Y10T436/218 ,  Y10T436/25375 ,  Y10T436/255

摘要： An analytical system for measuring the concentration of non-methane organic gases within a test sample including methane and non-methane component groups. In one version, a dual column analysis system utilizes a metal column and a porous layer open tubular (PLOT column to separate methane and non-methane organic gases (NMOG). The metal column captures non-methane compounds which are more easily thermally trapped on the metal column, generally higher molecular weight compounds and polar molecule, which prevents these compounds from contaminating the PLOT column. In another version, the system incorporates a single trap in the form of a porous layer open tubular (PLOT) column which the sample mixture is directed through and which traps the NMOG group through adsorption. The methane group passes through the trap and is vented to atmosphere or evaluated using a detector. After trapping of the NMOG group, the flow direction through the column is reversed and the column temperature is increased to desorb the NMOG group which is evaluated using a detector such as a flame ionization detector (FID).

摘要翻译： 用于测量包括甲烷和非甲烷组分组在内的测试样品中的非甲烷有机气体浓度的分析系统。 在一个版本中，双柱分析系统使用金属柱和多孔层开放管（PLOT柱来分离甲烷和非甲烷有机气体（NMOG）），金属柱捕获更易被热捕获的非甲烷化合物 金属柱，通常较高分子量的化合物和极性分子，可防止这些化合物污染PLOT柱。在另一个版本中，该系统包含多孔层开放管（PLOT）柱形式的单一阱，样品混合物 通过吸附捕获NMOG基团，甲烷组通过捕集器并排放到大气中或使用检测器进行评估，在捕获NMOG基团后，通过柱的流动方向相反，柱温为 增加到使用诸如火焰离子化检测器（FID）的检测器评估的NMOG组解吸。

公开(公告)号：EP0661537A3

公开(公告)日：1995-08-30

申请号：EP94306176.2

申请日：1994-08-22

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen ,  Peters, Anita Jo

IPC分类号： G01N30/12 ,  G01N30/40

CPC分类号： G01N30/12 ,  G01N30/40 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/123 ,  G01N2030/128 ,  G01N2030/3046 ,  G01N2030/383 ,  G01N2030/623 ,  G01N2030/3076 ,  G01N2030/3023

摘要： A gas chromatograph system (10) including a cold trap (12) having two portions (12a and 12b), a capillary tube (14) and a porous layer open tubular (PLOT) column (15), for substantially simultaneously trapping lower and higher boiling point gasses. The capillary tube (14) enables cold trapping of lower boiling point gasses while the PLOT column (15) enables cold trapping of higher boiling point gasses. The capillary tube interconnects at one end to an analytical column (20) and a sample gas source (26) and interconnects at its other end to a first end of the PLOT column (15). The other end of the PLOT column interconnects to a carrier gas source and a vacuum source. The capillary tube and PLOT column are both positioned within a temperature controlled environment of the cold trap. During the collection mode, the temperature control means maintains a relatively low temperature to condense the sample components. During injection of the sample from the cold trap to the analytical column, the temperature control means maintains a relatively high temperature to vaporize the sample components.

公开(公告)号：EP0661537A2

公开(公告)日：1995-07-05

申请号：EP94306176.2

申请日：1994-08-22

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen ,  Peters, Anita Jo

IPC分类号： G01N30/12 ,  G01N30/40

CPC分类号： G01N30/12 ,  G01N30/40 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/123 ,  G01N2030/128 ,  G01N2030/3046 ,  G01N2030/383 ,  G01N2030/623 ,  G01N2030/3076 ,  G01N2030/3023

摘要： A gas chromatograph system (10) including a cold trap (12) having two portions (12a and 12b), a capillary tube (14) and a porous layer open tubular (PLOT) column (15), for substantially simultaneously trapping lower and higher boiling point gasses. The capillary tube (14) enables cold trapping of lower boiling point gasses while the PLOT column (15) enables cold trapping of higher boiling point gasses. The capillary tube interconnects at one end to an analytical column (20) and a sample gas source (26) and interconnects at its other end to a first end of the PLOT column (15). The other end of the PLOT column interconnects to a carrier gas source and a vacuum source. The capillary tube and PLOT column are both positioned within a temperature controlled environment of the cold trap. During the collection mode, the temperature control means maintains a relatively low temperature to condense the sample components. During injection of the sample from the cold trap to the analytical column, the temperature control means maintains a relatively high temperature to vaporize the sample components.

摘要翻译： 一种气相色谱系统（10），包括具有两部分的冷阱，毛细管和多孔层开放管（PLOT）柱，用于基本上同时捕获较低沸点和较高沸点的气体。 毛细管能够冷藏低沸点气体，而PLOT柱可以冷却高沸点气体。 毛细管一端连接到分析柱和样品气体源，并在其另一端互连到PLOT柱的第一端。 PLOT列的另一端与载气源和真空源相互连接。 毛细管和PLOT柱均位于冷阱的温度控制环境内。 在收集模式期间，温度控制装置保持相对较低的温度以冷凝样品组分。 在将样品从冷阱注入分析柱期间，温度控制装置保持相对高的温度以蒸发样品组分。

公开(公告)号：EP0588505A3

公开(公告)日：1995-03-08

申请号：EP93306552.6

申请日：1993-08-19

申请人： CHROMATOFAST

发明人： Klemp, Mark Allen

IPC分类号： G01N33/00 ,  G01N30/00 ,  G01N27/62

CPC分类号： G01N33/0016 ,  G01N30/00 ,  G01N30/08 ,  G01N30/40 ,  G01N30/68 ,  G01N2030/121 ,  G01N2030/123 ,  G01N2030/383 ,  G01N2030/402

摘要： An analytical system for measuring the concentration of non-methane organic gases within a test sample including methane and non-methane component groups. The system incorporates a trap in the form of a porous layer open tubular (PLOT) column which the sample mixture is directed through and which traps the NMOG group through adsorption. The methane group passes through the trap and is vented to atmosphere or evaluated using a detector. After trapping of the NMOG group, the flow direction through the column is reversed and the column temperature is increased to desorb the NMOG group which is evaluated using a detector such as a flame ionization detector (FID).

摘要翻译： 用于测量包括甲烷和非甲烷组分组在内的测试样品中的非甲烷有机气体浓度的分析系统。 该系统包含多孔层开放管（PLOT）柱形式的捕集器，样品混合物被引导通过并通过吸附捕获NMOG基团。 甲烷组通过捕集器并排放到大气中或使用检测器进行评估。 在捕获NMOG基团后，通过柱的流动方向反转，柱温升高，以使用诸如火焰离子化检测器（FID）的检测器评价的NMOG基解吸。