公开(公告)号：EP3205667A1

公开(公告)日：2017-08-16

申请号：EP17156362.0

申请日：2017-02-15

Applicant: Purcell, Brendan Patrick ,  Williamson, David Thomas ,  Dai, Lixin ,  Cassingham, Darryl Miles ,  Spinella, Stephen M.

Inventor： Purcell, Brendan Patrick ,  Williamson, David Thomas ,  Dai, Lixin ,  Cassingham, Darryl Miles ,  Spinella, Stephen M.

IPC: C07K14/78 ,  D06N3/00 ,  D01F4/00 ,  D01F11/02

CPC classification number: C08J3/24 ,  B32B5/26 ,  C07K14/78 ,  C08J2389/06 ,  C14C9/00 ,  C14C9/02 ,  C14C13/00 ,  D01C3/00 ,  D01F4/00 ,  D04H1/00 ,  D04H1/4382 ,  D04H13/00 ,  D06M15/05 ,  D06M15/15 ,  D06M23/16 ,  D06M2101/06 ,  D06N3/00 ,  D06N3/0018 ,  D06N7/0097 ,  D06N2201/06 ,  D06N2203/02 ,  D06P3/32

Abstract: A biofabricated material containing a network of crosslinked collagen fibrils is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side ( e.g ., distal surface) to the other (proximal inner layers).

Abstract translation: 公开了含有交联胶原原纤维网络的生物制造材料。 该材料由也是天然皮革的主要成分的胶原组成，并且通过将胶原分子原纤维化成原纤维，使原纤维交联并润滑交联原纤维的过程生产。 与天然皮革不同，这种生物制造材料表现出非各向异性（非方向依赖性）的物理性质，例如，当在不同方向上拉伸或应力时，生物纤维材料片材可具有基本相同的弹性或拉伸强度。 与天然皮革不同，它具有均匀的质地，可促进染料和涂料的均匀吸收。 从美学角度而言，它可以产生均匀一致的纹理，便于可制造性。 它可以在不同于天然皮革的两侧具有基本相同的颗粒，纹理和其他美学性质，其中颗粒从一侧（例如远侧表面）到另一侧（近侧内层）增加。

公开(公告)号：EP3205666A1

公开(公告)日：2017-08-16

申请号：EP17156361.2

申请日：2017-02-15

Applicant: Purcell, Brendan Patrick ,  Williamson, David Thomas ,  Marga, Francoise Suzanne ,  Shofer, Susan J. ,  Cassingham, Darryl Miles

Inventor： Purcell, Brendan Patrick ,  Williamson, David Thomas ,  Marga, Francoise Suzanne ,  Shofer, Susan J. ,  Cassingham, Darryl Miles

IPC: C07K14/78 ,  D06N3/00 ,  D01F4/00 ,  D01F11/02

Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins. The collagen or collagen-like proteins are isolated from animal sources or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.

Abstract translation: 本文描述了一种从胶原蛋白或胶原蛋白样蛋白质生产生物制造材料的方法。 胶原蛋白或胶原蛋白样蛋白质是从动物来源分离的或通过重组DNA技术或通过化学合成产生的。 胶原蛋白或胶原蛋白样蛋白质被原纤化，交联，脱水和润滑，从而形成具有基本均匀的胶原纤维网络的生物制造材料。

公开(公告)号：EP2678397A1

公开(公告)日：2014-01-01

申请号：EP12713308.0

申请日：2012-02-16

Applicant: Cassingham, Darryl ,  Northants Leather Chemicals Ltd

Inventor： CASSINGHAM Darryl

IPC: C09D175/04 ,  C09D133/00 ,  C14C3/28 ,  C14C3/04 ,  C14C9/04 ,  C14C9/02 ,  C14C11/00 ,  D06M11/56 ,  D06M11/57 ,  D06N3/14

CPC classification number: C14C11/00 ,  B65D77/22 ,  C09D175/04 ,  C14C3/04 ,  C14C3/28 ,  C14C9/02 ,  C14C9/04 ,  C14C11/003 ,  C14C11/006 ,  D06M11/56 ,  D06M11/57 ,  D06N3/0056 ,  D06N3/042 ,  D06N3/12 ,  D06N3/128 ,  D06N3/14 ,  D06N3/144 ,  D06N2205/20 ,  D06N2211/10 ,  D06N2211/103 ,  D06N2211/106 ,  D06N2211/14 ,  D06N2211/28 ,  Y10T428/31511 ,  Y10T428/31663 ,  C08L33/00

Abstract: Coated Fibrous Substrates The present invention provides a method of improving the adhesion of coatings to fibrous base materials. The method comprises treating a fibrous base material with one or more salt(s) of receptor species to provide a pre-coated fibrous base material comprising specific inorganic receptor sites within the fibrous base material. The one or more salt(s) of receptor species is selected from the groups comprising: (a) aluminium salts; (b) titanium salts; (c) zirconium salts; (d) iron salts; (e) soluble alkali silicates; or a combination thereof. The method further comprises coating the treated fibrous base material with a coating formulation comprising one or more compound(s) containing epoxy and alkoxysilane groups. The coating formulation acts as an adhesion promoter and cross-linker.