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公开(公告)号：EP2651396B1
公开(公告)日：2017-07-12
申请号：EP11794739.0
申请日：2011-12-12
申请人： Novartis AG , Debiopharm S.A.
发明人： GONCALVES, Elisabete , RAPP, Karin , SUTTER, Bertrand , STOWASSER, Frank , TRUPP, Bjoern , CHABAUT, Sebastian , THORENS, Julien
CPC分类号： A61K38/13 , A61K9/0053 , A61K9/0095 , A61K9/107 , A61K9/1075 , A61K9/4858 , A61K47/10 , A61K47/14 , A61K47/22 , A61K47/26
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公开(公告)号：EP2303229A1
公开(公告)日：2011-04-06
申请号：EP09766241.5
申请日：2009-06-09
申请人： Debiopharm S.A.
发明人： MARX, Uwe , THORENS, Julien , BERNARD, Stéphane
IPC分类号： A61K9/08 , A61K47/36 , A61K47/40 , A61K31/282
CPC分类号： A61K9/0019 , A61K31/282 , A61K47/36 , A61K47/40
摘要： The present invention relates to a pharmaceutically stable and highly concentrated aqueous oxaliplatin solution. The present invention also concerns a method for preparing said solution.
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公开(公告)号：EP2215272B1
公开(公告)日：2011-02-23
申请号：EP08844624.0
申请日：2008-10-31
发明人： VUAGNIAUX, Grégoire , DUMONT, Jean-Maurice , SNOECK, Joke , VAN DOOREN, Sonia , VANDAMME, Anne-Mieke
IPC分类号： C12Q1/70
CPC分类号： C12Q1/707 , C12Q2521/107
摘要： The invention relates to assays for characterization of genotypic mutations of Hepatitis C Virus (HCV) showing a resistance to anti-HCV drugs.
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公开(公告)号：EP1792621A1
公开(公告)日：2007-06-06
申请号：EP05111534.3
申请日：2005-11-30
申请人： DEBIOPHARM S.A.
IPC分类号： A61K31/727 , A61K9/00
CPC分类号： A61K31/727
摘要： The invention relates to pharmaceutical compositions useful for oral administration comprising N-acetylated, oversulfated heparin characterized by the following parameters: percentage of N-acetylation >50%, degree of sulfation >2.5, weight average molecular weight comprised between 1,600 and 10,000.
摘要翻译： 本发明涉及用于口服给药的药物组合物，其包含N-乙酰化的过硫酸化肝素，其特征在于以下参数：N-乙酰化百分比> 50％，硫酸化度> 2.5，重均分子量在1600至10,000之间。
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公开(公告)号：EP1091975B1
公开(公告)日：2005-12-14
申请号：EP99926684.4
申请日：1999-06-30
申请人： DEBIOPHARM S.A.
摘要： The invention concerns a novel cyclosporin, its pharmaceutical use and a pharmaceutical composition containing it.
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公开(公告)号：EP0881226B1
公开(公告)日：2003-11-26
申请号：EP97929532.6
申请日：1997-07-04
申请人： DEBIOPHARM S.A.
发明人： OHNISHI, Yuko
IPC分类号： C07F15/00
CPC分类号： C07F15/0093
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公开(公告)号：EP1308453A3
公开(公告)日：2003-05-14
申请号：EP03000861.9
申请日：1996-10-18
申请人： DEBIOPHARM S.A.
发明人： Taniuchi, Jun-ichi, Tanaka Kikinzoku Kogyo K. K. , Nakanishi, Chihiro, Tanaka Kikinzoku Kogyo K. K. , Ohnishi, Yuko, Tanaka Kikinzoku Kogyo K. K.
IPC分类号： C07F15/00
CPC分类号： C07F15/0093
摘要： Disclosed herein are processes of preparing a platinum complex having a Formula II. For preventing the contamination of impurities, reaction environment is so controlled that oxidation is difficult to occur.
摘要翻译： 本文公开了制备具有式II的铂络合物的方法。 为了防止杂质污染，控制反应环境使得氧化难以发生。
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8.发明公开SUSPENSION OF AN EPI-HNE PROTEIN, PROCESS OF PREPARATION THEREOF, DRY POWDER AEROSOL DERIVED THEREFROM, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID SUSPENSION OR AEROSOL, AND THEIR USES 有权暂停含EPI-HNE蛋白，制作方法，MADE干粉气雾剂药物组合物的制品含有该暂停或将该气溶胶和用途
公开(公告)号：EP1223972A1
公开(公告)日：2002-07-24
申请号：EP01992586.6
申请日：2001-10-26
申请人： DEBIOPHARM S.A.
发明人： PONCIN, Alain , SAUDUBRAY, François , BOKMAN, Anne
CPC分类号： A61K9/0078 , A61K38/57
摘要： The present invention concerns a suspension of crystallized particles of an EPI-hNE protein, methods for preparing said suspension, a dry powder aerosol derived from said suspension, an inhalable pharmaceutical formulation comprising said suspension or said dry powder aerosol, and the use of said inhalable pharmaceutical formulation in the treatment of various pathological conditions.
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公开(公告)号：EP1121117B1
公开(公告)日：2002-06-05
申请号：EP99946400.1
申请日：1999-10-13
申请人： DEBIOPHARM S.A.
IPC分类号： A61K31/282 , A61K33/24 , A61K9/08 , A61K31/555 , A61P35/00
CPC分类号： A61K31/555 , A61K9/08 , A61K31/282 , A61K33/24
摘要： The invention concerns a liquid pharmaceutical preparation of oxiplatinum packaged in a container, preferably in a sealed soft bag for medical use. The liquid preparation of oxiplatinum can advantageously be presented in the form of a bag with several compartments containing doses of a ready-to-use solution.
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10.发明授权process of preparing a cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity 失效Verfahren zur Herstellung von Cis-Oxalato（Trans-L-1,2-Cyclohexandiamin）Pt Komplex mit hoher optischer Reinheit
公开(公告)号：EP0625523B1
公开(公告)日：2001-10-31
申请号：EP93830384.9
申请日：1993-09-16
申请人： DEBIOPHARM S.A.
发明人： Okamoto, Koji, c/o Tanaka Kikinzoku , Nakanishi, Chihiro, c/o Tanaka Kikinzoku , Taniushi, Junichi, c/o Tanaka Kikinzoku , Ohnishi, Junji, c/o Tanaka Kikinzoku , Komoda, Yasunibu, c/o Tanaka Kikinzoku
IPC分类号： C07F15/00 , A61K31/28 , C07C209/88
CPC分类号： C07F15/0093 , C07C209/88 , C07C2601/14
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