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公开(公告)号：EP2831220B1
公开(公告)日：2020-10-21
申请号：EP13769204.2
申请日：2013-03-28
申请人： Mitegen, LLC
IPC分类号： C12M1/18
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公开(公告)号：EP4407291A2
公开(公告)日：2024-07-31
申请号：EP24181409.4
申请日：2020-10-05
申请人： Mitegen, LLC
发明人： CLOSS, David , APKER, Benjamin , THORNE, Robert E.
IPC分类号： G01N1/42
CPC分类号： H01J37/20 , H01J2237/2620130101 , G01N35/00732 , G01N2001/403320130101 , G01N1/4022 , G01N1/42
摘要： Sample support design and sample cooling devices for single-particle cryo-electron microscopy that simplify sample preparation and handling, dramatically reduce errors and improve outcome reproducibility, and dramatically reduce overall costs. The system consisting of grid based sample support system, grid handling tools, grid blotting tools, a plunge cooling system, and jet cooling systems.
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公开(公告)号：EP3935372A1
公开(公告)日：2022-01-12
申请号：EP20767329.4
申请日：2020-03-06
申请人： Mitegen, LLC
IPC分类号： G01N23/20025 , G01B3/00 , G01N23/00 , G01N23/20 , G01N23/20008
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4.发明公开IMPROVEMENTS TO MICROPLATES AND METHODS FOR PROTEIN CRYSTALLIZATION AND BIOTECHNOLOGY 审中-公开改善主板和方法蛋白质微结晶与生物技术
公开(公告)号：EP2831220A4
公开(公告)日：2016-01-27
申请号：EP13769204
申请日：2013-03-28
申请人： MITEGEN LLC
发明人： THORNE ROBERT E , APKER BENJAMIN , NEWMAN ROBERT
IPC分类号： C12M1/18
CPC分类号： B01L3/5085 , B01L2200/0678 , B01L2300/0829 , B01L2300/0858 , B01L2300/0893 , C12M23/12 , C30B35/002
摘要： Devices and methods for manual and high-throughput protein crystal growth and growth of other biological and organic crystals. A microplate includes a plurality of cells and a frame that defines the cells in the microplate. In each cell there is at least one well open at top. Each well in a cell may be enclosed at bottom, or it may be open at bottom, in which case the well bottom may be sealed by a separate part, which may be, e.g., a separate film or plate (e.g., of plastic, glass or metal) or a molded part.
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公开(公告)号：EP4407291A3
公开(公告)日：2024-11-13
申请号：EP24181409.4
申请日：2020-10-05
申请人： Mitegen, LLC
发明人： CLOSS, David , APKER, Benjamin , THORNE, Robert E.
摘要： Sample support design and sample cooling devices for single-particle cryo-electron microscopy that simplify sample preparation and handling, dramatically reduce errors and improve outcome reproducibility, and dramatically reduce overall costs. The system consisting of grid based sample support system, grid handling tools, grid blotting tools, a plunge cooling system, and jet cooling systems.
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6.发明公开IMPROVEMENTS TO MICROPLATES AND METHODS FOR PROTEIN CRYSTALLIZATION AND BIOTECHNOLOGY 审中-公开改善主板和方法蛋白质微结晶与生物技术
公开(公告)号：EP2831220A1
公开(公告)日：2015-02-04
申请号：EP13769204.2
申请日：2013-03-28
申请人： Mitegen, LLC
IPC分类号： C12M1/18
CPC分类号： B01L3/5085 , B01L2200/0678 , B01L2300/0829 , B01L2300/0858 , B01L2300/0893 , C12M23/12 , C30B35/002
摘要： Devices and methods for manual and high-throughput protein crystal growth and growth of other biological and organic crystals. A microplate includes a plurality of cells and a frame that defines the cells in the microplate. In each cell there is at least one well open at top. Each well in a cell may be enclosed at bottom, or it may be open at bottom, in which case the well bottom may be sealed by a separate part, which may be, e.g., a separate film or plate (e.g., of plastic, glass or metal) or a molded part.
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公开(公告)号：EP4348694A1
公开(公告)日：2024-04-10
申请号：EP22816894.4
申请日：2022-06-03
申请人： Mitegen, LLC
发明人： THORNE, Robert , ENGSTROM, Tyler , JAYNE, Richard
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