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1.发明公开ADP-RIBOSYLATION INHIBITORS AND REMEDIES FOR ENDOTOXIC BACTERIAL ENTERIC INFECTION CONTAINING PROANTHOCYANIDIN AS THE ACTIVE INGREDIENT 审中-公开抑制剂ADP核糖基化和补救办法DUCK RISCHE细菌感染的内毒素原花青素为活动CONTAIN
公开(公告)号：EP1153604A4
公开(公告)日：2003-07-30
申请号：EP99903920
申请日：1999-02-15
发明人： NODA MASATOSHI , KANDA TOMOMASA , YANAGIDA AKIO , HIEDA KAZUO
IPC分类号： A23L1/30 , A61K31/35 , A61K31/352 , A61K31/353 , A61K31/78 , A61K36/73 , A61K36/87 , C07D311/62 , A61K35/78
CPC分类号： A61K31/78 , A23L33/105 , A23V2002/00 , A61K31/35 , A61K31/352 , A61K31/353 , A61K36/73 , A61K36/87 , A23V2250/2104
摘要： A composition for the treatment and/or prevention of enterotoxin type bacterial infectious disease comprising, as an active ingredient, a substance containing proanthocyanidin derived from a naturally occurring substance such as an apple or grape extract, which can inhibit toxins produced by enteric infection causative bacteria of enterotoxin type, e.g., pathogenic vibrios (Vibrio cholerae, Vibrio parahaemolyticus); and a composition for the treatment and/or prevention of diphtheria, etc. based on the ADP-ribosylation inhibiting activity of proanthocyanidin; as well as a food additive and foodstuff containing proanthocyanidin or the composition used for the treatment and prevention of these infectious diseases.
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2.发明公开ADP-RIBOSYLATION INHIBITORS AND REMEDIES FOR ENDOTOXIC BACTERIAL ENTERIC INFECTION CONTAINING PROANTHOCYANIDIN AS THE ACTIVE INGREDIENT 审中-公开抑制剂ADP核糖基化和补救办法DUCK RISCHE细菌感染的内毒素原花青素为活动CONTAIN
公开(公告)号：EP1153604A1
公开(公告)日：2001-11-14
申请号：EP99903920.9
申请日：1999-02-15
发明人： NODA, Masatoshi , KANDA, Tomomasa , YANAGIDA, Akio , HIEDA, Kazuo
CPC分类号： A61K31/78 , A23L33/105 , A23V2002/00 , A61K31/35 , A61K31/352 , A61K31/353 , A61K36/73 , A61K36/87 , Y02A50/469 , Y02A50/471 , A23V2250/2104
摘要： A composition for the treatment and/or prevention of enterotoxin type bacterial infectious disease comprising, as an active ingredient, a substance containing proanthocyanidin derived from a naturally occurring substance such as an apple or grape extract, which can inhibit toxins produced by enteric infection causative bacteria of enterotoxin type, e.g., pathogenic vibrios (Vibrio cholerae, Vibrio parahaemolyticus); and a composition for the treatment and/or prevention of diphtheria, etc. based on the ADP-ribosylation inhibiting activity of proanthocyanidin; as well as a food additive and foodstuff containing proanthocyanidin or the composition used for the treatment and prevention of these infectious diseases.
摘要翻译： 对于肠毒素型细菌感染性疾病的治疗和/或预防，其包含作为活性成分的组合物，从天然存在的物质衍生的物质，含有花色素原：如苹果或葡萄提取物，它可以抑制由肠道感染的致病细菌产生的毒素 肠毒素类型，例如，致病性弧菌（霍乱弧菌，副溶血性弧菌）; 以及用于基于所述治疗和/或预防白喉等的组合物中的ADP-核糖基化抑制原花色素的活性; 以及作为食品添加剂和食品材料含原花色素，或用于治疗和预防感染性疾病本文的组合物中。
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