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    Assay methods using hollow particles and kits containing them
    5.
    发明授权
    Assay methods using hollow particles and kits containing them 有权
    使用微粒空心体试验方法以及含有这些工具包

    公开(公告)号：EP1913390B1

    公开(公告)日：2012-05-30

    申请号：EP06789740.5

    申请日：2006-08-11

    Applicant: PerkinElmer LAS, Inc.

    Inventor： PATTON, Wayne, F.

    IPC: G01N33/573 ,  G01N33/553

    CPC classification number: G01N33/54313 ,  C12Q1/42 ,  C12Q1/485 ,  G01N33/542 ,  G01N33/54306 ,  G01N33/5432 ,  G01N33/5436 ,  G01N33/573 ,  G01N2333/9121 ,  G01N2333/916

    Abstract: The invention provides assay particles useful, for example, for detecting analytes and binding molecule interactions. One type of assay particle includes a core portion encased by a shell portion, wherein the shell portion comprises an inorganic phosphor that binds selectively to a target molecule. Another type of an assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the coat portion comprises an inorganic phosphor that binds selectively to a target molecule. A further type of assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the coat portion comprises an inorganic phosphor and a target selective binding moiety, and wherein the assay particle is buoyant in aqueous media. An additional type of assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the shell portion comprises an inorganic phosphor and the coat portion comprises a target selective binding moiety, and wherein the assay particle is buoyant in aqueous media. Also provided are kits and related methods.

    Hybrid film type sensor
    7.
    发明公开
    Hybrid film type sensor 审中-公开
    传感器vom Hybridfilmtyp

    公开(公告)号：EP2369332A1

    公开(公告)日：2011-09-28

    申请号：EP11164979.4

    申请日：2003-11-17

    Applicant: PerkinElmer LAS, Inc.

    Inventor： Prohaska, Otto J. ,  Laconti, Anthony B. ,  Giner, Jose C. ,  Manoukian, Mourad

    IPC: G01N27/49 ,  G01N27/407

    CPC classification number: G01N27/4045 ,  G01N27/4074 ,  G01N33/004

    Abstract: A miniaturized gas sensor comprised of thick- or thin-film type electrodes (4, 5, 6), on a non-conductive supportive substrate (1), and in contact with a solid ionomer electrolyte (8), for the detection of toxic gases, i.e., carbon monoxide, and other
    oxidizable or reducible gases and vapors is described. The all-solid planar sensor cell has two or more film type electrodes arranged on a non-conductive planar surface of a supportive substrate. The electrodes are discrete and in intimate contact with the same solid polymer ionomer membrane. The sensor cell contains no liquid electrolyte and is operated in a constant-voltage, potentiostatic or potentiodynamic mode. A high sensitivity to a select gas or vapor is achieved by a novel three-phase contact area design for a sensing electrode which provides contact with the solid ionomer electrolyte, as well as the gas sample via diffusion openings or holes that penetrate through the supportive substrate.

    Abstract translation: 一种小型化气体传感器，由厚或薄膜型电极（4,5,6）组成，在非导电支撑衬底（1）上，并与固体离聚物电解质（8）接触，用于检测有毒物质 描述了气体，即一氧化碳和其它可氧化或可还原的气体和蒸汽。 全固体平面传感器单元具有布置在支撑衬底的非导电平面表面上的两个或更多个膜型电极。 电极是离散的并且与相同的固体聚合物离聚物膜紧密接触。 传感器单元不含液体电解质，并以恒定电压，恒电位或电位动力学模式运行。 通过用于感测电极的新颖的三相接触面积设计来实现对选择气体或蒸气的高灵敏度，该设计提供与固体离聚物电解质的接触，以及通过穿透支撑衬底的扩散开口或孔的气体样品 。

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