METHOD FOR PRODUCING INSULIN FROM A NATURAL SOURCE AND INSULIN
    2.
    发明公开
    METHOD FOR PRODUCING INSULIN FROM A NATURAL SOURCE AND INSULIN 审中-公开
    用于生产胰岛素从自然来源及胰岛素

    公开(公告)号:EP1666048A4

    公开(公告)日:2009-07-01

    申请号:EP04788526

    申请日:2004-09-17

    CPC分类号: A61K38/28

    摘要: The inventive method for producing insulin consists in using a reindeer pancreas which is homogenised in a hydrochloride ethanol solution. Afterwards, the extraction associated with the subsequent clarification of the solution and a supernatant production is carried out. Said supernatant is exposed to an ion-exchange chromatography and isoelectric precipitation, thereby producing insulin which is purified by means of a high-efficient reversed-phase liquid chromatography. The thus produced insulin can compete for a bond with an insulin receptor at a concentration higher than 100 ng/ml.