公开(公告)号：EP2989671A4

公开(公告)日：2016-11-23

申请号：EP13882787

申请日：2013-04-27

申请人： UNIV SHANGHAI JIAOTONG ,  BOSCH GMBH ROBERT

发明人： YANG JUN ,  FENG XUEJIAO ,  ZHANG JINGJUN ,  ZHOU LONGJIE ,  DOU YUQIAN

IPC分类号： H01M4/38 ,  C04B35/626 ,  C04B35/628 ,  H01M4/1391 ,  H01M4/1395 ,  H01M4/1397 ,  H01M4/36 ,  H01M4/48 ,  H01M4/587 ,  H01M4/62 ,  H01M10/0525

CPC分类号： H01M4/366 ,  C04B35/62615 ,  C04B35/62839 ,  C04B35/62884 ,  C04B35/62897 ,  C04B2235/3418 ,  C04B2235/401 ,  C04B2235/428 ,  C04B2235/5436 ,  C04B2235/5472 ,  H01M4/0428 ,  H01M4/1391 ,  H01M4/1395 ,  H01M4/362 ,  H01M4/364 ,  H01M4/386 ,  H01M4/48 ,  H01M4/483 ,  H01M4/583 ,  H01M4/587 ,  H01M4/625 ,  H01M10/0525 ,  H01M2220/30

摘要： An SiOx/Si/C composite material, includes SiOx/Si composite particles and a carbon coating layer coated on the SiOx/Si composite particles. The SiOx/Si composite particles include nano-silicon crystallites embedded in an SiOx (0

公开(公告)号：EP3002276A4

公开(公告)日：2016-05-25

申请号：EP13871854

申请日：2013-06-25

申请人： UNIV SHANGHAI JIAOTONG

发明人： LI SHAOSHUN ,  WANG RUBING ,  ZHENG XIAOGANG ,  ZHANG XU

IPC分类号： C07C251/46 ,  A61K31/15 ,  A61K31/222 ,  A61K31/235 ,  A61K31/381 ,  A61K31/4402 ,  A61P35/00 ,  A61P35/02 ,  C07C249/08 ,  C07D213/79 ,  C07D213/803 ,  C07D333/38

CPC分类号： C07C251/34 ,  A61K31/15 ,  A61K31/222 ,  C07C249/08 ,  C07C251/46 ,  C07D213/79 ,  C07D333/40

摘要： The present invention discloses derivatives of shikonin, alkannin and a racemic mixture thereof with hydroxyl methylation and carbonyl oximation on the parent nucleus, and their application. The derivatives of shikonin with hydroxyl methylation and carbonyl oximation on the parent nucleus have structural formula (I) or (II); the derivatives of alkannin with hydroxyl methylation and carbonyl oximation on the parent nucleus have structural formula (III) or (IV); the derivatives of a racemic mixture of shikonin and alkannin with hydroxyl methylation and carbonyl oximation on the parent nucleus have structural formula (V) or (VI); wherein R 1 is alkane, olefin, arene, or substituted arene comprising 1 to 6 carbon atoms; and R 2 is alkane, olefin, arene, or substituted arene comprising 1 to 6 carbon atoms or is H. The oxime derivatives of shikonin, alkannin and a racemic mixture thereof in the present invention have novel structures; and in-vitro experiments show that said derivatives of the present invention have good growth inhibitory activity against tumor cells and thus can be used in tumor treatment.

公开(公告)号：EP2781512A4

公开(公告)日：2015-03-25

申请号：EP12849240

申请日：2012-11-09

申请人： UNIV SHANGHAI JIAOTONG ,  ZHEJIANG MED XINCHANG PHARM

发明人： LUO XIANJIN ,  YE WEIDONG

IPC分类号： C07D271/06 ,  A61K31/14 ,  A61K31/4245 ,  A61K31/425 ,  A61K31/427 ,  A61K31/433 ,  A61K31/501 ,  A61K31/506 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

CPC分类号： C07D417/12 ,  A61K31/4245 ,  C07D271/06 ,  C07D413/12 ,  C07D413/14 ,  C07D417/14

公开(公告)号：EP2494981A4

公开(公告)日：2014-03-12

申请号：EP10826072

申请日：2010-10-26

申请人： UNIV SHANGHAI JIAOTONG ,  SHANGHAI REGENOME BIOMEDICAL TECHNOLOGY CO LTD

发明人： HAN WEI ,  XIANG DI ,  WU ZHENQIAN

IPC分类号： A61K38/20 ,  A61P1/00 ,  A61P1/12

CPC分类号： A61K38/2006 ,  A61K38/1709 ,  C07K14/54

公开(公告)号：EP2187620A4

公开(公告)日：2013-10-23

申请号：EP08783573

申请日：2008-07-28

申请人： OMRON TATEISI ELECTRONICS CO ,  UNIV SHANGHAI JIAOTONG

发明人： ZHAO YUMING ,  LIU JIAPENG ,  XIAO YANFENG ,  SHEN FENG ,  SUWA MASAKI ,  KIMACHI MASATOSHI

IPC分类号： H04N5/217 ,  G06T5/00 ,  H04N1/409 ,  H04N5/14 ,  H04N5/20 ,  H04N5/21 ,  H04N5/235 ,  H04N5/243 ,  H04N9/64

CPC分类号： H04N9/646 ,  G06T5/002 ,  G06T5/20 ,  G06T2207/20028 ,  H04N1/409 ,  H04N5/20 ,  H04N5/21 ,  H04N5/2351 ,  H04N5/243

公开(公告)号：EP2436392A4

公开(公告)日：2012-10-31

申请号：EP10779997

申请日：2010-05-25

申请人： UNIV SHANGHAI JIAOTONG ,  SHANGHAI REGENOME BIOMEDICAL TECHNOLOGY CO LTD

发明人： HAN WEI ,  ZHANG ZHONGHUI

IPC分类号： A61K38/19 ,  A61F2/28 ,  A61F2/82 ,  A61L27/54 ,  A61P19/02 ,  A61P19/08

CPC分类号： A61L27/227 ,  A61F2/30756 ,  A61F2002/30677 ,  A61K38/18 ,  A61L27/54 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2430/06

摘要： The applications and medical devices of Midkine in the field of biotechnology are described in this invention. This invention describes the applications of the protein as follow in (a) or (b) in preparing drugs for promoting cartilage growth or treating cartilage diseases, the protein as a growth factor for promoting chondrocyte proliferation, or medical devices containing this protein: (a) the protein whose amino acid sequence is shown as SEQ ID NO.1; (b) the proteins whose amino acid sequence have at least 60% homology comparing with amino acid sequence described in (a) and have activity for promoting proliferation of chondrocyte. The protein described in this invention promotes proliferation of three types of chondrocytes and is used for preparing drugs for treating cartilage disease. It may provide new therapy for treating cartilage diseases clinically, and new technology for expansion of chondrocytes in vitro for cartilage tissue engineering.

公开(公告)号：EP2215107A4

公开(公告)日：2010-10-27

申请号：EP08849427

申请日：2008-11-05

申请人： UNIV SHANGHAI JIAOTONG

发明人： XU YUHONG ,  SONG SHUXIAN ,  LIU DAN

IPC分类号： C07K7/00 ,  A61K9/127 ,  A61K38/08 ,  A61K47/48 ,  A61P35/00 ,  C07K14/71 ,  C07K17/08

CPC分类号： A61K49/0084 ,  A61K9/1271 ,  A61K38/00 ,  A61K47/62 ,  A61K47/6911 ,  A61K49/0017 ,  A61K49/0032 ,  A61K49/0041 ,  A61K49/0043 ,  A61K49/0056 ,  B82Y5/00 ,  C07K7/06

公开(公告)号：EP1978037A4

公开(公告)日：2008-12-31

申请号：EP07702039

申请日：2007-01-11

申请人： SHANGHAI ALLRUN NANO SCIENCE A ,  UNIV SHANGHAI JIAOTONG

发明人： CUI LONGLAN ,  XU HONG ,  GU HONGCHEN

IPC分类号： C08F2/44 ,  C08F2/22 ,  C08F2/24

CPC分类号： C08F2/22

摘要： Polymerization process for preparing monodispersal organic/inorganic composite nano-microsphere in the field of nanometer technology is disclosed. The process comprises preparing two different miniemulsion systems of A with inorganic nanoparticles and B with polymerisable monomers in advance; adding water-soluble initiator into A, stirring till complete dissolution, then adding B to stir till mixing evenly;finally, heating the mixed system to a given temperature for isothermal reaction. The grain size of the superparamagnetic Fe 3 O 4 /polystyrene is homogeneous and controllable, and the magnetic particles content is controllable.

摘要翻译： 公开了纳米技术领域中制备单分散有机/无机复合纳米微球的聚合工艺。 该方法包括预先制备A与无机纳米颗粒和B与可聚合单体的两种不同的细乳液体系; 在A中加入水溶性引发剂，搅拌至完全溶解，然后加入B搅拌至混合均匀，最后将混合体系加热至给定温度进行等温反应。 超顺磁性Fe3O4 /聚苯乙烯粒径均匀可控，磁性粒子含量可控。

公开(公告)号：EP1443107A4

公开(公告)日：2005-01-26

申请号：EP01274634

申请日：2001-11-06

申请人： UNIV SHANGHAI 2ND MEDICAL ,  SHENG HUIZHEN

发明人： SHENG HUIZHEN ,  CHEN YING ,  YANG QINGZHANG

IPC分类号： C12N15/09 ,  A01K67/027 ,  A61K35/12 ,  A61K35/48 ,  A61L27/00 ,  C12N5/02 ,  C12N5/10 ,  C12N15/00 ,  C12N15/877 ,  C12N5/06 ,  C12N5/08

CPC分类号： C12N15/8777 ,  A01K2227/107

公开(公告)号：EP3098651A4

公开(公告)日：2017-04-12

申请号：EP14870645

申请日：2014-07-01

申请人： UNIV SHANGHAI JIAOTONG

发明人： ZOU WEIWEN ,  YANG SHUO ,  LONG XIN ,  CHEN JIANPING

IPC分类号： G02F1/35 ,  G01M11/00 ,  G02B6/42

CPC分类号： G01M11/31 ,  G01M11/3109 ,  G01M11/3145 ,  G01M11/3154 ,  G01M11/3172

摘要： An optical pulse compression reflectometer is provided, which comprises: a single wavelength continuous optical source, an optical splitter, a modulation frequency pulse generating module, an optical directional coupler, an optical fiber under test, an optical coupler, a balanced photodetecter, and a pulse compression processing module. The present invention, in addition to overcoming the contradictory constraint between spatial resolution and measurement range in traditional time domain reflectometry and giving to full play the super spatial resolution from frequency modulation technology, has a longer measurement range than that in the optical frequency domain reflectometry.