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17 条记录 (耗时 0.014 秒)

    MEDICAMENT DISPENSER AND METHOD OF MAKING AND USING IT
    3.
    发明公开
    MEDICAMENT DISPENSER AND METHOD OF MAKING AND USING IT 有权
    药物捐助者和其制造方法及用途

    公开(公告)号：EP2303718A1

    公开(公告)日：2011-04-06

    申请号：EP09767728.0

    申请日：2009-06-18

    申请人： Watson Laboratories, Inc.

    发明人： BITNER, John

    IPC分类号： B65D83/04

    CPC分类号： B65D83/0463 ,  A61J1/035 ,  B65D2203/00 ,  B65D2215/02

    摘要： A medicament dispenser can include a first side surface (14), a second side surface (16) spaced from and substantially opposed to the first side surface, and a medicament packaging structure (30) located between the first side surface and second side surface. A pivot structure (18) can extend between the first side surface and the second side surface, and the medicament packaging structure can be rotatable about the pivot structure. Thus, the medicament packaging structure can be rotated from an enclosed state in which the medicament packaging structure is substantially enclosed by the first side surface and/or second side surface, to an exposed state in which the medicament packaging structure is substantially exposed from at least one of the first side surface and/or second side surface to provide user access to the medicament (s) stored in the medicament packaging structure. A lock structure (10) can be located adjacent the first side surface and second side surface in order to selectively prevent movement and/or rotation of the medicament packaging structure. A method of using and making the medicament dispenser are also disclosed.

    STABILIZED NICOTINE CHEWING GUM
    8.
    发明公开
    STABILIZED NICOTINE CHEWING GUM 审中-公开
    稳压尼古丁口香糖

    公开(公告)号：EP2358362A1

    公开(公告)日：2011-08-24

    申请号：EP09832340.5

    申请日：2009-11-24

    申请人： Watson Laboratories, Inc.

    发明人： HITE, W. Crawford ,  BATHEJA, Malini ,  SADATREZAEI, Mohsen

    IPC分类号： A61K9/68

    CPC分类号： A61K31/4406 ,  A61K9/0058

    摘要： The present invention relates to a stable chewing gum composition comprising nicotine and a chewing gum base wherein the chewing gum composition is substantially free of any liquid containing non-bonded electron pairs that promote oxidation of nicotine free base In certain embodiments, the chewing gum composition is free of any liquid containing non-electron pairs that promote oxidation of nicotine free base.

    IMPROVED SYNTHESIS OF HEXAHYDRODIBENZOPYRANONES
    9.
    发明公开
    IMPROVED SYNTHESIS OF HEXAHYDRODIBENZOPYRANONES 审中-公开
    改进的六氢二苯并噻喃酮的合成

    公开(公告)号：EP2331519A1

    公开(公告)日：2011-06-15

    申请号：EP09809161.4

    申请日：2009-08-28

    申请人： Watson Laboratories, Inc.

    发明人： MIKAYLO, Valeriy ,  PARAMANANTHAM, Subakar ,  AVRUTOV, Ilya ,  BROWN, Martyn, A. ,  LI, Zemin ,  LAZAROWYCH, Natalie

    IPC分类号： C07D311/80

    CPC分类号： C07D311/80

    摘要： The current application relates to an improved process for the synthesis of a 6a, 10a-cis-hexahydrodibenzo[b,d]pyran-9-one derivative, such as nabilone, by condensing a 5-substituted resorcinol with a 1-alkoxy-4-(1 -hydroxy-1-methylethyl)-1,4-cyclohexadiene in the presence of a Lewis acid selected from triflic anhydride, triflic acid, and sulfuric acid. The starting 1,4-cyclohexadiene derivative is prepared by an improved Birch reduction process in which a benzene derivative is reacted with gaseous ammonia, an alcohol, and an alkaline metal such as lithium, sodium, or potassium.

    摘要翻译： 目前的应用涉及通过使5-取代的间苯二酚与1-烷氧基-4,6-二氢吡喃-4-酮缩合而合成6a，10a-顺式 - 六氢二苯并[b，d]吡喃-9-酮衍生物如萘啶酮的改进方法 - （1-羟基-1-甲基乙基）-1,4-环己二烯在选自三氟甲磺酸酐，三氟甲磺酸和硫酸的路易斯酸存在下反应。 起始的1,4-环己二烯衍生物通过改进的Birch还原方法制备，其中苯衍生物与气态氨，醇和碱金属如锂，钠或钾反应。