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公开(公告)号:EP2334646A2
公开(公告)日:2011-06-22
申请号:EP09792591.1
申请日:2009-09-16
申请人: Abbott Laboratories
发明人: CARROLL, William A , DART, Michael J. , FROST, Jennifer M. , LATSHAW, Steven P. , KOLASA, Teodozyj , LI, Tongmei , PEDDI, Sridhar , LIU, Bo , PEREZ-MEDRANO, Arturo , PATEL, Meena , WANG, Xueqing , NELSON, Derek W.
IPC分类号: C07D231/40 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14
CPC分类号: C07D405/12 , C07D231/40 , C07D285/135 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12
摘要: Disclosed herein are cannabinoid receptor ligands of formula (I), wherein A
1 , A
5 , R
x , X
4 , and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.-
公开(公告)号:EP2376462A1
公开(公告)日:2011-10-19
申请号:EP09775056.6
申请日:2009-12-16
申请人: Abbott Laboratories
发明人: FROST, Jennifer, M. , LATSHAW, Steven, P. , DART, Michael, J. , CARROLL, William, A. , PEREZ-MEDRANO, Arturo , KOLASA, Teodozyj , PATEL, Meena , NELSON, Derek, W. , LI, Tongmei , PEDDI, Sridhar , WANG, Xueqing , LIU, Bo
IPC分类号: C07D277/46 , C07D417/12 , C07D513/04 , A61K31/426 , A61K31/427 , A61K31/428 , A61P3/04 , A61P3/10 , A61P9/00 , A61P11/00 , A61P29/00 , A61P35/00
CPC分类号: C07D417/12 , C07D277/46 , C07D513/04
摘要: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein L
1 , A
1 , R
1g , z, R
2 , R
3 , and R
4 are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.-
公开(公告)号:EP2346843A2
公开(公告)日:2011-07-27
申请号:EP09792301.5
申请日:2009-09-08
申请人: Abbott Laboratories
发明人: CARROLL, William, A. , DART, Michael, J. , FROST, Jennifer, M. , KOLASA, Teodozyj , LI, Tongmei , LIU, Bo , PEREZ-MEDRANO, Arturo , PATEL, Meena , WANG, Xueqing , PEDDI, Sridhar
IPC分类号: C07D277/46 , C07D417/06 , C07D417/14 , A61K31/427 , A61P29/00
CPC分类号: C07D417/06 , C07D277/46 , C07D417/14
摘要: The present application relates to cannabinoid receptor ligands of formula (I), wherein X
1 , A
1 , R
x , R
2 , R
3 , R
4 , and z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions.-
公开(公告)号:EP2219629A1
公开(公告)日:2010-08-25
申请号:EP08837396.4
申请日:2008-10-08
申请人: Abbott Laboratories
发明人: CARROLL, William A. , PEDDI, Sridhar , PEREZ-MEDRANO, Arturo , DART, Michael J. , NELSON, Derek W. , LI, Tongmei , LIU, Bo , KOLASA, Teodozyj , FROST, Jennifer , WANG, Xueqing , LATSHAW, Steven, P.
IPC分类号: A61K31/015 , A61P43/00
CPC分类号: C07D405/06 , C07D405/14 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/14
摘要: The present invention relates compounds of formula (I), as defined in the specification, pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions.
摘要翻译: 本发明涉及如说明书中所定义的式(I)化合物,包含此类化合物的药物组合物,以及使用此类化合物和药物组合物治疗病症和障碍的方法。
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公开(公告)号:EP2411382A1
公开(公告)日:2012-02-01
申请号:EP10724166.3
申请日:2010-03-26
申请人: Abbott Laboratories
发明人: CARROLL, William A , DART, Michael J. , FROST, Jennifer M. , LATSHAW, Steven P. , LI, Tongmei , LIU, Bo , PEDDI, Sridhar , WANG, Xueqing , KOLASA, Teodozyj , NELSON, Derek W. , PEREZ-MEDRANO, Arturo
IPC分类号: C07D405/06 , C07D413/06 , C07D417/06 , A61K31/433 , A61P25/04
CPC分类号: C07D417/06 , C07D405/06 , C07D413/06
摘要: Disclosed herein are compounds of formula (I) wherein Ring A and R
1 are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and pharmaceutical compositions are also disclosed.-
公开(公告)号:EP2331516B1
公开(公告)日:2013-03-13
申请号:EP09791365.1
申请日:2009-08-11
申请人: ABBOTT LABORATORIES
发明人: CARROLL, William, A. , DART, Michael, J. , FROST, Jennifer, M. , KOLASA, Teodozyj , LATSHAW, Steven, P. , LIU, Bo , PATEL, Meena, V. , PEREZ-MEDRANO, Arturo , WANG, Xueqing
IPC分类号: C07D261/14 , C07D407/06 , C07D417/06 , C07D285/135 , A61K31/433 , A61P29/00
CPC分类号: C07D261/14 , C07D285/135 , C07D407/06 , C07D417/06
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公开(公告)号:EP2411371A1
公开(公告)日:2012-02-01
申请号:EP10724168.9
申请日:2010-03-26
申请人: Abbott Laboratories
发明人: WANG, Xueqing , DART, Michael, J. , LIU, Bo
IPC分类号: C07D231/40 , C07D285/135 , A61K31/433 , A61P25/04
CPC分类号: C07D231/40 , C07D285/135
摘要: Cannabinoid receptor ligands of formula (I) wherein Ring A and R1 are as defined in the specification. Compositions including such compounds, and methods of treating conditions and disorders using such compounds and compositions are also described.
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公开(公告)号:EP2411370A1
公开(公告)日:2012-02-01
申请号:EP10724167.1
申请日:2010-03-26
申请人: Abbott Laboratories
发明人: WANG, Xueqing , FROST, Jennifer, M. , DART, Michael, J. , LIU, Bo
IPC分类号: C07D231/40 , C07D403/12 , C07D285/135 , A61K31/433 , A61P25/04
CPC分类号: C07D231/40 , C07D285/135 , C07D403/12
摘要: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Ring A and R1 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also described.
摘要翻译: 本文公开了式(I)的大麻素受体配体,其中环A和R 1如说明书中所定义。 还描述了包含此类化合物的组合物以及使用此类化合物和组合物治疗疾病和病症的方法。
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9.
公开(公告)号:EP2331516A1
公开(公告)日:2011-06-15
申请号:EP09791365.1
申请日:2009-08-11
申请人: ABBOTT LABORATORIES
发明人: CARROLL, William, A. , DART, Michael, J. , FROST, Jennifer, M. , KOLASA, Teodozyj , LATSHAW, Steven, P. , LIU, Bo , PATEL, Meena, V. , PEREZ-MEDRANO, Arturo , WANG, Xueqing
IPC分类号: C07D261/14 , C07D407/06 , C07D417/06 , C07D285/135 , A61K31/433 , A61P29/00
CPC分类号: C07D261/14 , C07D285/135 , C07D407/06 , C07D417/06
摘要: Disclosed herein are cannabinoid receptor ligands of formula (I), wherein Y, X
1 , X
2 , X
3 , R
1 , and R
2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
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