公开(公告)号：EP2376462A1

公开(公告)日：2011-10-19

申请号：EP09775056.6

申请日：2009-12-16

申请人： Abbott Laboratories

发明人： FROST, Jennifer, M. ,  LATSHAW, Steven, P. ,  DART, Michael, J. ,  CARROLL, William, A. ,  PEREZ-MEDRANO, Arturo ,  KOLASA, Teodozyj ,  PATEL, Meena ,  NELSON, Derek, W. ,  LI, Tongmei ,  PEDDI, Sridhar ,  WANG, Xueqing ,  LIU, Bo

IPC分类号： C07D277/46 ,  C07D417/12 ,  C07D513/04 ,  A61K31/426 ,  A61K31/427 ,  A61K31/428 ,  A61P3/04 ,  A61P3/10 ,  A61P9/00 ,  A61P11/00 ,  A61P29/00 ,  A61P35/00

CPC分类号： C07D417/12 ,  C07D277/46 ,  C07D513/04

摘要： Disclosed herein are cannabinoid receptor ligands of formula (I) wherein L
1 , A
1 , R
1g , z, R
2 , R
3 , and R
4 are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.

公开(公告)号：EP2331516B1

公开(公告)日：2013-03-13

申请号：EP09791365.1

申请日：2009-08-11

申请人： ABBOTT LABORATORIES

发明人： CARROLL, William, A. ,  DART, Michael, J. ,  FROST, Jennifer, M. ,  KOLASA, Teodozyj ,  LATSHAW, Steven, P. ,  LIU, Bo ,  PATEL, Meena, V. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing

IPC分类号： C07D261/14 ,  C07D407/06 ,  C07D417/06 ,  C07D285/135 ,  A61K31/433 ,  A61P29/00

CPC分类号： C07D261/14 ,  C07D285/135 ,  C07D407/06 ,  C07D417/06

公开(公告)号：EP2411370A1

公开(公告)日：2012-02-01

申请号：EP10724167.1

申请日：2010-03-26

申请人： Abbott Laboratories

发明人： WANG, Xueqing ,  FROST, Jennifer, M. ,  DART, Michael, J. ,  LIU, Bo

IPC分类号： C07D231/40 ,  C07D403/12 ,  C07D285/135 ,  A61K31/433 ,  A61P25/04

CPC分类号： C07D231/40 ,  C07D285/135 ,  C07D403/12

摘要： Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Ring A and R1 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also described.

摘要翻译： 本文公开了式（I）的大麻素受体配体，其中环A和R 1如说明书中所定义。 还描述了包含此类化合物的组合物以及使用此类化合物和组合物治疗疾病和病症的方法。

公开(公告)号：EP2331516A1

公开(公告)日：2011-06-15

申请号：EP09791365.1

申请日：2009-08-11

申请人： ABBOTT LABORATORIES

发明人： CARROLL, William, A. ,  DART, Michael, J. ,  FROST, Jennifer, M. ,  KOLASA, Teodozyj ,  LATSHAW, Steven, P. ,  LIU, Bo ,  PATEL, Meena, V. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing

IPC分类号： C07D261/14 ,  C07D407/06 ,  C07D417/06 ,  C07D285/135 ,  A61K31/433 ,  A61P29/00

CPC分类号： C07D261/14 ,  C07D285/135 ,  C07D407/06 ,  C07D417/06

摘要： Disclosed herein are cannabinoid receptor ligands of formula (I), wherein Y, X
1 , X
2 , X
3 , R
1 , and R
2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

公开(公告)号：EP2160393A1

公开(公告)日：2010-03-10

申请号：EP08755491.1

申请日：2008-05-15

申请人： Abbott Laboratories

发明人： DART, Michael, J. ,  CARROLL, William, A. ,  PEREZ-MEDRANO, Arturo ,  PEDDI, Sridhar ,  FROST, Jennifer, M.

IPC分类号： C07D513/04 ,  A61K31/429 ,  A61P29/00 ,  A61P37/00

CPC分类号： A61K31/429 ,  C07D513/04

摘要： The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, and R4 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

公开(公告)号：EP2346843A2

公开(公告)日：2011-07-27

申请号：EP09792301.5

申请日：2009-09-08

申请人： Abbott Laboratories

发明人： CARROLL, William, A. ,  DART, Michael, J. ,  FROST, Jennifer, M. ,  KOLASA, Teodozyj ,  LI, Tongmei ,  LIU, Bo ,  PEREZ-MEDRANO, Arturo ,  PATEL, Meena ,  WANG, Xueqing ,  PEDDI, Sridhar

IPC分类号： C07D277/46 ,  C07D417/06 ,  C07D417/14 ,  A61K31/427 ,  A61P29/00

CPC分类号： C07D417/06 ,  C07D277/46 ,  C07D417/14

摘要： The present application relates to cannabinoid receptor ligands of formula (I), wherein X
1 , A
1 , R
x , R
2 , R
3 , R
4 , and z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions.

公开(公告)号：EP2274306A1

公开(公告)日：2011-01-19

申请号：EP09719609.1

申请日：2009-03-11

申请人： Abbott Laboratories

发明人： KOLASA, Teodozyi ,  FROST, Jennifer, M. ,  PATEL, Meena, V. ,  LATSHAW, Steven, P. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing ,  TIETJE, Karin, Rose, Marie ,  PEDDI, Sridhar ,  CARROLL, William, A.

IPC分类号： C07D417/06 ,  A61K31/426

CPC分类号： C07D417/06

摘要： Disclosed herein are compounds of formula (I) wherein R
1 , R
2 , R
3 , R
25a , R
26a , X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described.