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公开(公告)号：EP1783218A4
公开(公告)日：2009-02-18
申请号：EP05755873
申请日：2005-06-24
发明人： YAGI SHINTARO , YAMAGUCHI KENJIRO , ORI KENICHI , TANAKA EIJI , KIYOSAWA KENDO , MAKI NOBORU
CPC分类号： C07K14/005 , C07K16/109 , C12N15/70 , C12N2770/24222
摘要： A truncated form of hepatitis C virus gene obtained by deleting a portion of a region of a gene encoding NS2 protein from the core protein of hepatitis C virus while sustaining its translation frame. In particular, a gene as described above wherein the above-described portion of a region of the gene is located in a region encoding E1 protein and E2 protein.
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公开(公告)号：EP1783211A4
公开(公告)日：2007-08-08
申请号：EP04746550
申请日：2004-06-22
发明人： MAKI NOBORU , KIMURA TATSUJI , MATSUMOTO AKIHIRO , ROKUHARA AKINORI , TANAKA EIJI , KIYOSAWA KENDO
IPC分类号： C12N7/00 , C12Q1/70 , G01N33/53 , G01N33/576
CPC分类号： G01N33/5761 , C12N7/00 , C12N2730/10111 , C12N2730/10143 , C12Q1/706
摘要： Hepatitis B virus (HBV) particles in a bodily fluid sample containing HBV-RNA but no HBV-DNA; a method of measuring the particles as claimed in claim 1 by measuring HBV-RNA; a method of evaluating the therapeutic effect on HBV infection of a drug having an RNA-dependent DNA polymerase inhibitory effect characterized in that the above measurement is carried out on a bodily fluid of a patient under the corresponding therapy; and a method of presuming the risk of liver caner onset or selecting a risk group of liver cancer onset.
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