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1.发明授权
公开(公告)号：EP2257275B1
公开(公告)日：2011-12-28
申请号：EP09716497.4
申请日：2009-03-03
申请人： Allergan, Inc.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-ming , GRAHAM, Richard S. , WELTY, Devin F.
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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2.发明公开
公开(公告)号：EP2257275A2
公开(公告)日：2010-12-08
申请号：EP09716497.4
申请日：2009-03-03
申请人： Allergan, Inc.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-ming , GRAHAM, Richard S. , WELTY, Devin F.
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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公开(公告)号：EP1753434B2
公开(公告)日：2017-12-27
申请号：EP06738208.5
申请日：2006-03-14
申请人： ALLERGAN, INC.
发明人： CHANG, Chin-ming , CHANG, James, N. , SCHIFFMAN, Rhett, M. , JORDAN, R., Scott , CHANG-LIN, Joan-En
IPC分类号： A61K31/5575 , A61K9/00 , A61K47/18 , A61P27/06
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：EP1753434B1
公开(公告)日：2009-05-13
申请号：EP06738208.5
申请日：2006-03-14
申请人： ALLERGAN, INC.
发明人： CHANG, Chin-ming , CHANG, James, N. , SCHIFFMAN, Rhett, M. , JORDAN, R., Scott , CHANG-LIN, Joan-En
IPC分类号： A61K31/5575 , A61K9/00 , A61K47/18 , A61P27/06
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：EP1753434A2
公开(公告)日：2007-02-21
申请号：EP06738208.5
申请日：2006-03-14
申请人： ALLERGAN, INC.
发明人： CHANG, Chin-ming , CHANG, James, N. , SCHIFFMAN, Rhett, M. , JORDAN, R., Scott , CHANG-LIN, Joan-En
IPC分类号： A61K31/5575 , A61K9/00 , A61K47/18 , A61P27/06
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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