公开(公告)号：EP1511516A1

公开(公告)日：2005-03-09

申请号：EP03755048.0

申请日：2003-05-27

申请人： ALTANA Pharma AG

发明人： BOLLE, Christina ,  LINDER, Rudolf

IPC分类号： A61K47/10 ,  A61K47/14 ,  A61K47/06 ,  A61K47/32 ,  A61K47/44 ,  A61K31/44

CPC分类号： A61K9/107 ,  A61K9/0014 ,  A61K9/0043 ,  A61K9/0048 ,  A61K9/06 ,  A61K9/7023 ,  A61K31/44

摘要： A topical pharmaceutical preparation for administering a slightly soluble PDE 4 inhibitor is described. A surprisingly good systemic bioavailability is observed with this dosage form.

公开(公告)号：EP1796668A1

公开(公告)日：2007-06-20

申请号：EP05794694.9

申请日：2005-09-21

申请人： Altana Pharma AG

发明人： LINDER, Rudolf

IPC分类号： A61K31/44 ,  A61K9/08 ,  A61K9/00 ,  A61K47/14

CPC分类号： A61K9/0019 ,  A61K9/0043 ,  A61K9/0048 ,  A61K9/08 ,  A61K31/44 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14

摘要： An aqueous pharmaceutical preparation for administration of a slightly soluble PDE 4 inhibitor is described.

公开(公告)号：EP1658073A1

公开(公告)日：2006-05-24

申请号：EP04766541.9

申请日：2004-08-19

申请人： ALTANA Pharma AG

发明人： LIPPERT, Rita ,  LINDER, Rudolf

IPC分类号： A61K31/44 ,  A61J3/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/1412 ,  A61K9/0019 ,  A61K31/44 ,  A61K31/4439 ,  A61K47/02 ,  A61K47/183 ,  B65D39/0005 ,  B65D51/002

摘要： The present invention is related to pharmaceutical product for injection comprising a container including a closure suitable for preparations for injection, the container containing an acid labile proton pump inhibitor, a salt thereof, a solvate of the acid labile proton pump inhibitor or a salt thereof, wherein the container and closure are made of material which essentially does not release zinc ions.

公开(公告)号：EP1341528A1

公开(公告)日：2003-09-10

申请号：EP01999360.9

申请日：2001-12-06

申请人： ALTANA Pharma AG

发明人： DIETRICH, Rango ,  LINDER, Rudolf ,  NEY, Hartmut

IPC分类号： A61K9/20 ,  A61K9/16 ,  A61K31/44

CPC分类号： A61K9/2081 ,  A61K9/1617 ,  A61K31/4439

摘要： A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.

公开(公告)号：EP0566601B2

公开(公告)日：2007-02-21

申请号：EP92901804.2

申请日：1992-01-04

申请人： ALTANA Pharma AG

发明人： BELLER, Klaus-Dieter ,  LINDER, Rudolf

IPC分类号： A61K49/00

CPC分类号： A61K49/223 ,  A61K49/227

公开(公告)号：EP1037607B1

公开(公告)日：2004-02-25

申请号：EP98966609.4

申请日：1998-12-08

申请人： ALTANA Pharma AG

发明人： LINDER, Rudolf ,  DIETRICH, Rango

IPC分类号： A61K9/02 ,  A61K31/44

CPC分类号： A61K9/2081 ,  A61K9/0007 ,  A61K9/0031 ,  A61K9/025 ,  A61K9/1617 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2077 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5047 ,  A61K31/4439

摘要： A new administration form for acid-labile active compounds is described. The administraton form is a suppository, in particular for rectal administration.

公开(公告)号：EP1341527A1

公开(公告)日：2003-09-10

申请号：EP01999359.1

申请日：2001-12-06

申请人： ALTANA Pharma AG

发明人： DIETRICH, Rango ,  LINDER, Rudolf ,  NEY, Hartmut

IPC分类号： A61K9/20 ,  A61K9/16 ,  A61K31/44 ,  A61K9/48

CPC分类号： A61K9/2081 ,  A61K9/1617 ,  A61K9/4858 ,  A61K31/4439

摘要： The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation an active ingredient is present essentially uniformly dispersed in an excipient matrix composed of one or more excipients selected from the group of fatty alcohol, triglyceride, partial glyceride and fatty acid ester.

公开(公告)号：EP1796633A1

公开(公告)日：2007-06-20

申请号：EP05787168.3

申请日：2005-09-21

申请人： Altana Pharma AG

发明人： LINDER, Rudolf

IPC分类号： A61K9/08

CPC分类号： A61K31/44 ,  A61K9/0019 ,  A61K47/02 ,  A61K47/10 ,  A61K47/183

摘要： An aqueous pharmaceutical preparation for administration of a slightly soluble PDE 4 inhibitor is described.

公开(公告)号：EP1511481A1

公开(公告)日：2005-03-09

申请号：EP03730122.3

申请日：2003-05-27

申请人： ALTANA Pharma AG

发明人： KOENEN, Rüdiger ,  LINDER, Rudolf

IPC分类号： A61K31/44 ,  A61P27/02

CPC分类号： A61K9/107 ,  A61K9/0014 ,  A61K9/0043 ,  A61K9/0048 ,  A61K9/06 ,  A61K9/7023 ,  A61K31/44

摘要： A topical pharmaceutical preparation for administering a slightly soluble PDE 4 inhibitor is described. A surprisingly good systemic bioavailability is observed with this dosage form.

公开(公告)号：EP1037634B1

公开(公告)日：2005-09-07

申请号：EP98965801.8

申请日：1998-12-08

申请人： ALTANA Pharma AG

发明人： LINDER, Rudolf ,  DIETRICH, Rango

IPC分类号： A61K31/44 ,  A61K9/50

CPC分类号： A61K9/2081 ,  A61K9/0007 ,  A61K9/0031 ,  A61K9/025 ,  A61K9/1617 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2077 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5047 ,  A61K31/4439

摘要： Novel administration form for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.