公开(公告)号：EP1853251A4

公开(公告)日：2010-01-13

申请号：EP06735282

申请日：2006-02-16

申请人： ANACOR PHARMACEUTICALS INC

发明人： BAKER STEPHEN J ,  AKAMA TSUTOMU ,  BELLINGER-KAWAHARA CAROLYN ,  HERNANDEZ VINCENT S ,  HOLD KARIN M ,  LEYDEN JAMES J ,  MAPLES KIRK R ,  PLATTNER JACOB J ,  SANDERS VIRGINIA ,  ZHANG YONG-KANG

IPC分类号： C07F5/02 ,  A61K31/69 ,  A61P31/10

CPC分类号： C07F5/025 ,  A61K9/0012 ,  A61K31/69 ,  C07F5/02 ,  C07F5/027

公开(公告)号：EP1976536A4

公开(公告)日：2011-03-02

申请号：EP06801794

申请日：2006-08-16

申请人： ANACOR PHARMACEUTICALS INC

发明人： BAKER STEPHEN J ,  AKAMA TSUTOMU ,  ALLEY MICHAEL RICHARD KEVIN ,  BENKOVIC STEPHEN J ,  DIPIERRO MICHAEL ,  HERNANDEZ VINCENT S ,  HOLD KARIN M ,  KENNEDY ISAAC ,  LIKHOTVORIK IGOR ,  MAO WEIMIN ,  MAPLES KIRK R ,  PLATTNER JACOB J ,  ROCK FERNANDO ,  SANDERS VIRGINIA ,  STEMPHOSKI AARON M ,  YIANNIKOUROS GEORGE PETROS ,  ZEGAR SIEAD ,  ZHANG YONG-KANG ,  ZHOU HUCHEN

IPC分类号： A01N55/08 ,  A61K31/69 ,  C02F1/50 ,  C07F5/04 ,  C07H17/08 ,  C10L1/14

CPC分类号： C07F5/025 ,  A61K9/0012 ,  A61K9/08 ,  A61K31/69 ,  A61K31/70 ,  A61K31/7076 ,  A61K47/10 ,  C07F5/04 ,  C07H19/06 ,  C07H19/16 ,  C07H21/00 ,  C07H23/00

摘要： This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.