公开(公告)号：EP1055123A4

公开(公告)日：2004-12-01

申请号：EP99905927

申请日：1999-02-09

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： G01N33/48 ,  B01L3/00 ,  G01N1/28 ,  G01N35/02 ,  G02B21/34

CPC分类号： B01L3/508 ,  B01L2300/0822 ,  G02B21/34

摘要： An analytical plate such as a microscope slide (10) having an upper surface (12) and a lower surface (14). Disposed upon a portion of the upper surface (12) is a liquid containment border (16).

公开(公告)号：EP1888739A4

公开(公告)日：2012-07-18

申请号：EP06771115

申请日：2006-05-24

申请人： ANGROS LEE H ,  BYERS THOMAS L

发明人： ANGROS LEE H ,  BYERS THOMAS L

IPC分类号： G01N21/00 ,  B01L7/00 ,  G01N1/31 ,  G01N33/543

CPC分类号： G01N1/30 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0063 ,  A61F2007/126 ,  B01L7/00 ,  B01L7/52 ,  B01L2200/16 ,  B01L2300/0822 ,  B01L2300/14 ,  B01L2400/0478 ,  G01N1/28 ,  G01N1/312 ,  G01N1/44 ,  G01N35/00029 ,  G01N35/026 ,  G01N2035/00138 ,  G01N2035/0412 ,  Y10T436/25

摘要： Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable heating plate. Each slide support element preferably supports a single microscope slide. Each microscope slide can be enclosed within an individual pressurizable reaction compartment. Pressures exceeding 1 atm or below 1 atm can be created and maintained in the reaction compartment prior to, during or after heating of the slide begins. Because of the ability to pressurize and regulate pressure within the reaction compartment, and to individually heat each slide, each slide and a liquid solution or reagent thereon can be heated to temperatures that could not be obtained without the enclosed pressurized environment of the reaction compartment. A reagent dispensing strip having a plurality of reconfigurable reagent modules may also be used.

公开(公告)号：EP1991900A4

公开(公告)日：2010-11-10

申请号：EP06826510

申请日：2006-10-24

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： G02B21/34

CPC分类号： G02B21/34

公开(公告)号：EP2969968A4

公开(公告)日：2016-12-14

申请号：EP14764755

申请日：2014-03-17

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： C02F1/40 ,  G01N1/28 ,  G01N1/30 ,  G01N1/31 ,  G01N1/36

CPC分类号： G01N1/286 ,  G01N1/30 ,  G01N1/312 ,  G01N1/36 ,  G01N1/44

摘要： A method of removing a floatation liquid from between a microscope slide and a paraffin embedded biological specimen including position the microscope slide with the paraffin embedded biological specimen floated thereon onto a slide support element. The slide support element is rotated to cause the microscope slide and the paraffin embedded biological specimen to turn in a way that causes the floatation liquid disposed between the microscope slide and the paraffin embedded biological specimen to be drawn from between the microscope slide and the paraffin embedded biological specimen.

公开(公告)号：EP2062045A4

公开(公告)日：2010-05-05

申请号：EP07837343

申请日：2007-08-25

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： B01L99/00 ,  G01N33/48 ,  C12M1/18

CPC分类号： G01N1/30 ,  B01L3/5082 ,  B01L3/545 ,  B01L3/5453 ,  B01L2300/0822 ,  C09D5/32

公开(公告)号：EP1874485A4

公开(公告)日：2012-10-03

申请号：EP06750302

申请日：2006-04-14

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： B05C11/10 ,  B01L3/00 ,  B01L99/00 ,  B05C1/02 ,  B05C11/02 ,  B05C13/02 ,  G01N33/52

CPC分类号： G01N1/30 ,  B01L3/0258 ,  B01L3/508 ,  B01L99/00 ,  B01L2200/12 ,  B01L2300/0822 ,  B01L2300/16 ,  B01L2300/161 ,  B05C1/025 ,  B05C9/06 ,  B05C9/14 ,  B05C11/028 ,  B05C13/02 ,  B05D1/02 ,  B05D1/20 ,  B05D1/28 ,  B05D7/5483 ,  B05D2252/04 ,  G01N2001/305 ,  Y10T156/179 ,  Y10T156/1798

摘要： An apparatus and method for producing a coated analytic substrate using a compact and portable automated instrument located in the laboratory setting at the point of use which can consistently produce one or a plurality of coated analytic substrates “on demand” for using the analytic substrate immediately after coating, preferably without a step of rinsing the coated analytic substrate before use. The apparatus preferably uses applicator cartridges having a reservoir containing the coating compositions used to form the coatings. Preferably the cartridges are removable and interchangeable to facilitate the production of individual analytic substrates having different coatings or different coating patterns. These coated analytic substrates have superior specimen adhesion characteristics due to the improved quality of the coatings applied by the coating apparatus and due to the quickness with which the coated analytic substrates can be used in the lab after production.

摘要翻译： 一种用于使用位于实验室设置中的紧凑且便携式的自动化仪器来生产涂覆的分析基底的装置和方法，该实验室设置可以“按需”一致性地产生一个或多个涂覆的分析基底，以便立即使用分析底物 优选在使用前没有漂洗涂覆的分析基材的步骤。 该设备优选地使用具有包含用于形成涂层的涂料组合物的储存器的涂布器盒。 优选地，盒是可拆卸的和可互换的，以便于生产具有不同涂层或不同涂层图案的各个分析基底。 这些涂布的分析基材由于涂覆设备施加的涂层的质量提高，并且由于涂层分析基材可以在生产后在实验室中使用的快速性而具有优异的样品粘附特性。

公开(公告)号：EP1208378A4

公开(公告)日：2005-06-22

申请号：EP00947135

申请日：2000-07-07

申请人： ANGROS LEE H

发明人： ANGROS LEE H

IPC分类号： G01N1/31 ,  G01N33/52

CPC分类号： G01N1/30 ,  B01L9/52 ,  G01N1/312 ,  G01N1/44 ,  G01N33/52 ,  G01N33/521 ,  G01N33/53 ,  G01N33/5306 ,  G01N35/00029 ,  G01N35/00584 ,  G01N2035/00138 ,  G01N2035/00346 ,  Y10T436/11 ,  Y10T436/110833 ,  Y10T436/111666 ,  Y10T436/112499 ,  Y10T436/114165 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/25 ,  Y10T436/2575

摘要： An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. The reaction conditions for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide.