摘要:
A method of creating small particles by a technology referred to here as 'violent focusing' is disclosed, along with devices for generating such violent focusing. In general, the method comprises the steps of forcing a first fluid out of an exit opening of the feeding channel to create a fluid stream. The exit opening is positioned such that the fluid flowing out of the channel flows toward and out of an exit orifice of a pressure chamber which surrounds the exit opening of the feeding channel, and is filled with an atomizing fluid. An atomizing fluid such as a gas is directed towards the first fluid stream in approximately orthogonal directions and surrounding the circumference of the first fluid stream from all sides. The first fluid flow is broken into particles which have dimensions which are smaller than the dimensions of this fluid stream.
摘要:
A method of creating small particles by a technology referred to here as 'violent focusing' is disclosed, along with devices for generating such violent flow focusing. In general, the method comprises the steps of forcing a liquid (9) out of the exit opening (6) of the feeding tube (5) to create a liquid stream. The exit opening (6) is positioned such that the liquid (9) flowing out of the tube (5) flows toward and out of an exit orifice (7) of a pressure chamber (10) which surrounds the exit opening (6) of the feeding tube (5). The liquid flow is broken into particles (18) which have dimensions which are smaller than the dimensions of the liquid stream.
摘要:
A portable air temperature controlling device (40) useful for warming air surrounding an aerosolized drug formulation (16). Warming the air of an aerosol makes it possible to reduce the diameter of aerosol particles produced by an aerosol generation device. Additionally, warming the air forces the diameter of the aerosol particles to be in the range required for systemic drug delivery independent of ambient conditions. Smaller particles can be more precisely targeted to different areas of the respiratory tract.