公开(公告)号：EP2482797B1

公开(公告)日：2018-09-12

申请号：EP10757436.0

申请日：2010-09-28

申请人： Glaxo Group Limited

发明人： TRILL, Helen Mary ,  SPANO, William Fredrick

IPC分类号： A61K9/00 ,  A61M15/00 ,  B65D83/14

CPC分类号： A61M15/009 ,  A61K9/008 ,  A61M2202/062 ,  B65D83/54

摘要： The invention provides a pMDI metering valve comprising at least one component which comprises a desiccant-entrained material, a pMDI closed container system containing a desiccant-entrained material, and a method of stabilising the fine particle mass (FPM) of an inhalation drug formulation emitted by a pMDI closed container system comprising providing a desiccant-entrained material inside the pMDI closed container system so as to be in contact with the formulation therein.

公开(公告)号：EP2618875B1

公开(公告)日：2017-12-27

申请号：EP10857616.6

申请日：2010-09-24

申请人： Yeates, Donovan B.

发明人： Yeates, Donovan B.

IPC分类号： A61M11/02 ,  A61M15/02 ,  B05B1/06 ,  A61M11/06 ,  A61M15/00 ,  A61M16/00 ,  B05B12/00 ,  A61M11/00

CPC分类号： B05B12/00 ,  A61M11/003 ,  A61M11/042 ,  A61M11/06 ,  A61M15/0086 ,  A61M16/0066 ,  A61M2016/0015 ,  A61M2016/0039 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/3372 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2206/14

摘要： A method and an apparatus are described for generating a concentrated aerosol. A first heated volume flow of pressurized gas, a second volume flow of preheated dilution gas, and a third volume flow of fluid are provided. After creating a droplet aerosol from a solution, the aerosol solvent is quickly evaporated for creating a powder aerosol that then concentrated with a virtual impactor. The apparatus comprises a low flow resistance and achieves a high evaporation rate. The apparatus comprises a flow conditioner, nozzle, nozzle holder, and a concentrator.

公开(公告)号：EP1791584B1

公开(公告)日：2016-01-20

申请号：EP05786868.9

申请日：2005-08-19

申请人： Sanofi SA

发明人： Alfred von Schuckmann

IPC分类号： A61M15/00

CPC分类号： A61M15/0001 ,  A61M15/0005 ,  A61M15/0006 ,  A61M15/002 ,  A61M15/0021 ,  A61M15/0025 ,  A61M15/0065 ,  A61M15/0086 ,  A61M15/0091 ,  A61M2202/062 ,  A61M2202/064

公开(公告)号：EP2878327A1

公开(公告)日：2015-06-03

申请号：EP13822661.8

申请日：2013-07-24

申请人： Korea Research Institute of Chemical Technology

发明人： LEE, Kyu Hong ,  HEO, Yong Ju

IPC分类号： A61M15/00 ,  A61M11/02

CPC分类号： A61M11/003 ,  A61M11/005 ,  A61M11/02 ,  A61M11/042 ,  A61M11/06 ,  A61M15/0021 ,  A61M15/0085 ,  A61M15/009 ,  A61M16/1085 ,  A61M16/16 ,  A61M2202/06 ,  A61M2202/062 ,  A61M2205/75 ,  A61M2205/7536

摘要： The present invention relates to an apparatus for inhalation of medicine, in which particles in a medicinal aqueous solution, in a liquid aerosol form, are converted to dry medicinal particles by removing moisture therefrom by means of an evaporation unit so as to be inhaled,thereby allowing medicinal particles to penetrate deeply along the respiratory track to the lungs, and thus can be used in the treatment of lung diseases or a variety of other treatments using same, and in which an evaporation unit is structured so that an air compressor used in an aerosol unit is used to supply dry air thereto, thereby obviating an additional and separate device therefor, and thus the apparatus for inhalation is simplified, manufacturing thereof is facilitated and the manufacturing cost thereof is reduced.

摘要翻译： 本发明涉及一种药物吸入装置，其中以液体气溶胶形式的药用水溶液中的颗粒通过蒸发单元从其中除去水分而被转化为干燥的药用颗粒，从而被吸入，由此 允许药用颗粒沿着呼吸道深深地穿透到肺部，因此可以用于治疗肺部疾病或使用它们的各种其他治疗，并且其中蒸发单元被构造成使得用于 气雾单元用于向其供应干燥空气，从而避免了附加和分离的装置，因此简化了吸入装置，便于其制造，并降低其制造成本。

公开(公告)号：EP2101848B1

公开(公告)日：2014-04-16

申请号：EP07856741.9

申请日：2007-12-14

申请人： Jagotec AG

发明人： ZANGERLE, Wolfgang

IPC分类号： A61M15/00 ,  A61M11/00 ,  A61M16/00

CPC分类号： A61M15/0065 ,  A61M11/002 ,  A61M15/002 ,  A61M15/0021 ,  A61M15/0026 ,  A61M15/0076 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0091 ,  A61M2016/0039 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/215 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/8206 ,  A61M2205/825

公开(公告)号：EP2566550A1

公开(公告)日：2013-03-13

申请号：EP11728969.4

申请日：2011-04-13

申请人： Bilgic, Mahmut

发明人： Bilgic, Mahmut

IPC分类号： A61M15/00

CPC分类号： A61M15/0045 ,  A61M15/0021 ,  A61M15/0026 ,  A61M15/0043 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0075 ,  A61M15/0081 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/276 ,  A61M2206/16

摘要： The present invention relates to an inhaler which is appropriate for delivering the medicament in dry powder form used in the treatment of respiratory diseases, particularly in asthma, chronic obstructive pulmonary disease (COPD) and allergic rhinitis by the oral route and has a mechanism preventing the problems resulting from inadvertent actuation of the device.

公开(公告)号：EP2558148A1

公开(公告)日：2013-02-20

申请号：EP11720618.5

申请日：2011-04-13

申请人： Bilgic, Mahmut

发明人： Bilgic, Mahmut

IPC分类号： A61M15/00

CPC分类号： A61M15/0045 ,  A61M15/0021 ,  A61M15/0026 ,  A61M15/0043 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0075 ,  A61M15/0081 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/276

摘要： The present invention relates to an inhaler comprising blister package which is appropriate for effective and safe delivery of the medicament in dry powder form used in the treatment of respiratory diseases, particularly in asthma, chronic obstructive pulmonary disorder (COPD) and allergic rhinitis by the inhalation route.

摘要翻译： 本发明涉及包含泡罩包装的吸入器，其适于有效且安全地输送用于治疗呼吸疾病，特别是哮喘，慢性阻塞性肺病（COPD）和吸入过敏性鼻炎的干粉形式的药物 路线。

公开(公告)号：EP2521584A1

公开(公告)日：2012-11-14

申请号：EP11732098.6

申请日：2011-01-05

申请人： MicroDose Therapeutx, Inc.

发明人： AKOUKA, Henri, M. ,  BECKER, Daniel, P.

IPC分类号： A61M15/00 ,  A61M16/00

CPC分类号： A61M15/0051 ,  A61M15/001 ,  A61M15/0021 ,  A61M15/0043 ,  A61M15/0045 ,  A61M15/005 ,  A61M15/0055 ,  A61M15/0065 ,  A61M15/0085 ,  A61M2016/0021 ,  A61M2202/0266 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/0294 ,  A61M2205/12 ,  A61M2205/8206 ,  A61M2250/00

摘要： The present disclosure provides a method and device for delivering a pharmaceutical to the airway of a human or animal patient. In one aspect, the device includes a dose drum formed into a cylinder and including a plurality of dose compartments for containing individual doses. In another aspect, the device may include a reservoir containing a pharmaceutical material in bulk form and a metering recess for metering the pharmaceutical material to form a pharmaceutical dose. Another aspect provides an inhaler with a combined reservoir and dosing chamber configured to contain multiple doses of a pharmaceutical material.

公开(公告)号：EP2491970A2

公开(公告)日：2012-08-29

申请号：EP12157438.8

申请日：2005-08-24

申请人： Ethicon Endo-Surgery, Inc.

发明人： Bruggeman, Paul J. ,  Donofrio, William T. ,  Eyster, Curt R. ,  Flaker, Richard W. ,  Hickle, Randall S. ,  Katz, Hal H. ,  Keilholz, David J. ,  Krogh, Ross ,  Kulle, Lee K. ,  McRorie, Johnson, W, Jr. ,  Miller, Michael J. ,  Adair, William P. ,  Nalagatla, Anill K. ,  Niklewski, Paul J. ,  Privitera, Salvatore ,  Sabo, Louis ,  Stevens, Fred, B. III ,  Wuennemann, Jeffrey, J. ,  Cobb, Nicholas, E. ,  Martin, James F. ,  Bishop, Gregory D. ,  Burdorff, Mark A. ,  Burford, Charles B. ,  Collins, William, L., Jr. ,  Cushing, Tommy C. ,  Davis, DeWayne A. ,  Derouen, Jason P.

IPC分类号： A61M5/142 ,  A61M5/172 ,  A61M15/08 ,  A61M16/00 ,  A61B5/083 ,  A61M15/00 ,  A61M16/06 ,  A61M5/162

CPC分类号： A61M5/142 ,  A61B5/0836 ,  A61B5/411 ,  A61B5/6819 ,  A61B5/682 ,  A61B5/7495 ,  A61M5/14228 ,  A61M5/162 ,  A61M5/16831 ,  A61M5/172 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/0493 ,  A61M16/0672 ,  A61M16/0677 ,  A61M16/0688 ,  A61M16/0808 ,  A61M16/085 ,  A61M16/0858 ,  A61M21/02 ,  A61M2016/0027 ,  A61M2016/1025 ,  A61M2021/0027 ,  A61M2202/0208 ,  A61M2202/048 ,  A61M2202/062 ,  A61M2205/05 ,  A61M2205/12 ,  A61M2205/123 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/273 ,  A61M2205/3334 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/505 ,  A61M2205/6072 ,  A61M2205/7536 ,  A61M2209/084 ,  A61M2210/0618 ,  A61M2210/0625 ,  A61M2210/0662 ,  A61M2230/04 ,  A61M2230/06 ,  A61M2230/205 ,  A61M2230/30 ,  A61M2230/432 ,  A61M2230/63 ,  G06F19/00 ,  G06Q50/22 ,  G06Q50/24

摘要： A medical effector system comprised of a bedside unit (300) and a procedure unit (200). The bedside unit contains connection points for an oral nasal cannula and for receiving inputs from a series of patient monitors. The procedure unit contains a patient monitoring and a medical effector program, and a drug delivery pump and drug cassette or a magnetic flux generator capable of delivering therapeutic energy to a patient. The medical effector program operates the pump or magnetic flux generator based upon at least some of the patient outputs and program inputs. A removable umbilical cable (160) connects the two units and allows gases, the patient monitors as well as other information to travel between the two units.

摘要翻译： 一种由床边单元（300）和程序单元（200）组成的医用效应器系统。 床边单元包含用于口腔鼻插管的连接点并用于接收一系列患者监护仪的输入。 程序单元包括患者监测和医疗效应器程序，以及能够向患者输送治疗能量的药物输送泵和药物盒或磁通量发生器。 医疗效应器程序基于至少一些患者输出和程序输入来操作泵或磁通量发生器。 可拆卸的脐带缆（160）连接两个单元并允许气体，患者监视以及其他信息在两个单元之间行进。

公开(公告)号：EP1993644B1

公开(公告)日：2012-05-23

申请号：EP07726709.4

申请日：2007-03-08

申请人： Von Schuckmann, Alfred

发明人： Von Schuckmann, Alfred

IPC分类号： A61M15/00

CPC分类号： A61M15/0065 ,  A61M15/0066 ,  A61M15/0073 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/106

摘要： The invention relates to an inhalator (1) for powdery substances (33), especially medical substances. Said inhalator comprises a substance reservoir chamber (27) and a metering chamber (34) receiving a defined amount of the substance. The metering chamber is configured as a crossbore (35) of a rod (36) and can be displaced from a filling position (B) to a discharge position (E), in which discharge position (E) the metering chamber (34) is positioned in an air flow channel (21). The aim of the invention is to provide an inhalator of the aforementioned type which allows the metering chamber to be emptied in a manner that is optimal for the patient. For this purpose, the rod (36) has a plurality of metering chambers (34), arranged one behind the after on the rod (36). Said chambers reach the discharge position (E), preferably one by one, during a discharge actuation, and can be blown out one by one as intermingling small portions (instead of one large one) by the effect of the positive air pressure in the air flow channel (21).

摘要翻译： 本发明涉及一种用于粉末状物质（33）的吸入器（1），特别是医用物质。 所述吸入器包括接收限定量的物质的物质储存室（27）和计量室（34）。 计量室构造成杆（36）的横孔（35）并且可从填充位置（B）移位到排放位置（E），计量室（34）的排放位置 位于气流通道（21）中。 本发明的目的是提供一种上述类型的吸入器，其允许以对患者最佳的方式排空剂量室。 为此目的，杆（36）具有多个计量室（34），所述多个计量室（34）布置在杆（36）的后面一个后面。 所述腔室在排出致动期间优选地一个接一个地到达排出位置（E），并且可以通过空气中的正气压的作用而逐个吹出作为混合的小部分（而不是一个大的部分） 流动通道（21）。