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1.发明授权An antiviral 1-phenyl-2,5-dibenzimidazol-5-yl-pyrrolidine derivative 有权抗病毒剂2,5-二苯并咪唑-5-基-1-苯基 - 吡咯烷酮
公开(公告)号：EP2692346B1
公开(公告)日：2015-12-02
申请号：EP13191041.6
申请日：2011-10-12
申请人： AbbVie Bahamas Ltd.
发明人： Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L , Krueger, Allan C. , Randolph, John T. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachel V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Gao, Yi , Liu, Dachun , Pratt, John K. , Rockway, Todd W. , Maring, Clarence J. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Rolf , Tufano, Michael D. , Betebenner, David A. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Sebel H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary E. , Carroll, William A.
IPC分类号： A61K31/454 , A61P31/14
CPC分类号： A61K31/4184 , A61K31/4178 , A61K31/422 , A61K31/435 , A61K31/4355 , A61K31/438 , A61K31/4418 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D491/113 , C07F7/02 , Y02P20/582
摘要： Compounds effective in inhibiting replication of Hepatitis C virus (HCV) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译： 描述了有效抑制丙型肝炎病毒（HCV）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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公开(公告)号：EP2455376B1
公开(公告)日：2014-11-26
申请号：EP12155991.8
申请日：2010-06-10
申请人： AbbVie Bahamas Ltd.
发明人： Randolph, John T. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Degoey, David A. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary, E. , Gao, Yi , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E , Nelson, Lissa T. , Patel, Sachin V.
IPC分类号： C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
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公开(公告)号：EP2853531A2
公开(公告)日：2015-04-01
申请号：EP14190636.2
申请日：2010-06-10
申请人： AbbVie Bahamas Ltd.
发明人： Randolph, John T. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Degoey, David A. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary, E. , Gao, Yi , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E , Nelson, Lissa T. , Patel, Sachin V.
IPC分类号： C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译： 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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4.发明公开Trisubstituted heterocycles as replication inhibitors of hepatitis C virus HCV 有权Trisubstituierte Heterocyclen als Inhibitoren der Hepatitis C Virus HCV Replikation
公开(公告)号：EP2628481A1
公开(公告)日：2013-08-21
申请号：EP13167828.6
申请日：2010-06-10
申请人： AbbVie Bahamas Ltd.
发明人： Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel.D. , Bellizzi, Mary, E. , Gao, Yi
IPC分类号： A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4439 , A61P31/14 , C07D401/14 , C07D417/14 , C07D403/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译： 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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5.发明公开
公开(公告)号：EP2725015A1
公开(公告)日：2014-04-30
申请号：EP13193524.9
申请日：2008-09-17
申请人： AbbVie Bahamas Ltd.
发明人： Wagner, Rolf , Tufano, Michael D. , Stewart, Kent D. , Rockway, Todd W. , Randolph, John T. , Pratt, John K. , Motter, Christopher E. , Maring, Clarence J. , Longenecker, Kenton L. , Liu, Yaya , Liu, Dachun , Krueger, Allan C. , Kati, Warren M. , Hutchinson, Douglas K. , Huang, Peggy P. , Flentge, Charles A. , Donner, Pamela L. , Degoey, David A. , Betebenner, David A. , Barnes, David M. , Chen, Shuang , Franczyk II, Thaddeus S , Gao, Yi , Haight, Anthony R , Hengeveld, John E , Henry, Rodger F , Kotecki, Brian J , Lou, Xiaochun , Sarris, Kathy , Zhang, Geoff G. Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61P31/12 , A61K31/513
CPC分类号： A61K31/513 , A61K31/5377 , C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , C07D417/14
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia , inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; and (e) use of such compounds, salts, and compositions.
摘要翻译： 本发明涉及：（a）特别是抑制HCV的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备此类中间体，化合物，盐和组合物的方法; 和（e）使用这些化合物，盐和组合物。
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6.发明授权Trisubstituted heterocycles as replication inhibitors of hepatitis C virus HCV 有权三 - 取代的杂环如丙型肝炎病毒HCV复制的抑制剂
公开(公告)号：EP2628481B1
公开(公告)日：2016-02-24
申请号：EP13167828.6
申请日：2010-06-10
申请人： AbbVie Bahamas Ltd.
发明人： Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel.D. , Bellizzi, Mary, E. , Gao, Yi
IPC分类号： A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4439 , A61P31/14 , C07D401/14 , C07D417/14 , C07D403/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
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公开(公告)号：EP2853531A3
公开(公告)日：2015-08-12
申请号：EP14190636.2
申请日：2010-06-10
申请人： AbbVie Bahamas Ltd.
发明人： Randolph, John T. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Degoey, David A. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary, E. , Gao, Yi , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E , Nelson, Lissa T. , Patel, Sachin V.
IPC分类号： C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译： 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这些化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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