专利检索 ap:("Abbott GmbH & Co. KG") AND inv:"MUNSCHAUER, Rainer" 第 1 页

1.

发明授权
4-AMINOPYRROLOPYRIMIDINES AS KINASE INHIBITORS 有权
标题翻译： 4- AMINOPYRROLOPYRIMIDINE作为激酶抑制剂的

公开(公告)号：EP1114052B1

公开(公告)日：2005-11-16

申请号：EP99969414.4

申请日：1999-09-17

申请人： Abbott GmbH & Co. KG

发明人： CALDERWOOD, David , ARNOLD, Lee, D. , MAZDIYASNI, Hormoz , HIRST, Gavin , DENG, Bojuan, B. , TWIGGER, Helen, L. , MUNSCHAUER, Rainer , RAFFERTY, Paul , TOMETZKI, Gerald, B. , JOHNSTON, David, N.

IPC分类号： C07D487/04 , A61K31/505

CPC分类号： C07D487/04

摘要： Chemical compounds having structural formula (I) and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the kinases whose activity is inhibited by these compounds are involved in immunologic, hyperproliferative or angiogenic processes. Thus, these compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferative is a factor. These compounds can be used to treat cancer, hyperproliferation disorders, rheumatoid arthritis, disorders of the immune system, transplant rejection, and inflammatory disorders.

2.

发明授权
N-SUBSTITUIERTE AZABICYCLOHEPTAN-DERIVATE UND IHRE VERWENDUNG, Z.B., ALS NEUROLEPTIKA 失效
标题翻译： N-取代AZABICYCLOHEPTAN衍生物及其用途，例如，作为抗精神病药

公开(公告)号：EP0740658B1

公开(公告)日：2003-07-02

申请号：EP95901436.6

申请日：1994-11-26

申请人： Abbott GmbH & Co. KG

发明人： STEINER, Gerd , MUNSCHAUER, Rainer , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , HÖGER, Thomas

IPC分类号： C07D209/52 , A61K31/40 , C07D409/04 , C07D209/90 , C07D403/06 , C07D409/06 , C07D405/06 , C07D403/04 , C07D413/06 , C07D209/46 , C07D209/96

CPC分类号： C07D209/52

3.

发明授权
VERFAHREN ZUR HERSTELLUNG VON (+)-EXO-6-PHENYL-3-AZABICYCLO- 3.2.0|HEPTANEN 有权
标题翻译：用于生产（+） - EXO-6-苯基-3-氮杂双环3.2.0 |庚烷

公开(公告)号：EP1123278B1

公开(公告)日：2006-06-21

申请号：EP99953799.6

申请日：1999-10-13

申请人： Abbott GmbH & Co. KG

发明人： BISCHOF, Norbert , BUSCHMANN, Ernst , HENNINGSEN, Michael , KREI, Georg, Arnold , MUNSCHAUER, Rainer , PFEIFFER, Thomas , STEINER, Gerd , VIERGUTZ, Wolfgang

IPC分类号： C07D209/52 , C07B37/10

CPC分类号： C07D209/52

摘要： The invention relates to a method for producing (+)-exo-6-phenyl-3-azabicyclo-[3.2.0]heptanes of formula (I) in which R represents hydrogen, chlorine, bromine, fluorine or methoxy. The inventive compounds are characterized in that a bisallyl ammonium salt of formula (II), in which R has the above-mentioned meanings and X represents an anion, is photo-cyclized in an inert solvent while adding a sensitizer in a glass apparatus, and the selected (+)-exo-isomer (I) is precipitated as ditoluoyl tartrate using (-)-ditoluoyl tartaric acid from the obtained mixture, and this ditoluoyl tartrate is optionally recrystallized out of an alcohol/water mixture.

4.

发明授权
N-SUBSTITUIERTE 3-AZABICYCLO(3.2.0)HEPTAN-DERIVATE ALS NEUROLEPTIKA 失效
标题翻译： N-取代的3-氮杂双环（3.2.0）庚烷衍生物作为抗精神病药

公开(公告)号：EP0775135B1

公开(公告)日：2003-06-04

申请号：EP95926970.5

申请日：1995-07-21

申请人： Abbott GmbH & Co. KG

发明人： STEINER, Gerd , MUNSCHAUER, Rainer , HÖGER, Thomas , UNGER, Liliane , TESCHENDORF, Hans-Jürgen

IPC分类号： C07D403/06 , A61K31/40

CPC分类号： C07D403/06 , C07D471/04 , C07D513/04