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公开(公告)号：EP2509588B1
公开(公告)日：2019-05-01
申请号：EP10801645.2
申请日：2010-12-09
IPC分类号： A61K9/50 , A23L33/105 , A23L33/12 , A23L33/15 , A23L33/155 , A23L33/16 , A23K40/30 , A23K20/174 , A23K20/24
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公开(公告)号：EP2509588A1
公开(公告)日：2012-10-17
申请号：EP10801645.2
申请日：2010-12-09
CPC分类号： A61K9/5057 , A23K20/174 , A23K20/24 , A23K20/30 , A23K40/30 , A23K50/30 , A23L33/105 , A23L33/12 , A23L33/15 , A23L33/155 , A23L33/16 , A23P10/30 , A23P10/35 , A61K9/1658 , A61K9/1694 , A61K9/5089
摘要： The invention relates to a method for producing fat-soluble active principles, in particular pharmaceutical and/or dietary fat-soluble active principles, in the form of particles. The invention is characterized in that said method comprises the following steps: a) preparation of an oil-in-water emulsion comprising, in weight per cent relative to the total weight of said emulsion: between 8 and 20%, preferably between 10 and 15%, of at least one protein, between 5 and 15%, preferably between 8 and 12%, of at least one sugar, between 0.5 and 3%, preferably between 2 and 3%, of at least one inorganic salt, between 10 and 22%, preferably between 15 and 20%, of at least one fat-soluble active principle in oily form and/or dissolved in an edible oil, and qs for % of water; b) formation of essentially spherical particles by the dispersion of the oil-in-water emulsion obtained at the end of step a) in a fluid; c) addition of at least one protein cross-linking agent to the dispersion obtained at the end of step b); and d) recovery of the active principles in the essentially spherical form.
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