公开(公告)号：EP1789547A1

公开(公告)日：2007-05-30

申请号：EP05772660.6

申请日：2005-08-10

申请人： Ajinomoto Co., Inc.

发明人： KOZLOV, Yury, Ivanovich ,  CHINEN, Akito, Ajinomoto Co., Inc. ,  IZUI, Hiroshi, Ajinomoto Co., Inc. ,  HARA, Yoshihiko, Ajinomoto Co., Inc. ,  YASUEDA, Hisashi, Ajinomoto Co., Inc. ,  RYBAK, Konstantin Vyacheslavovich ,  SLIVINSKAYA, Ekaterina Aleksandrovna ,  KATASHKINA, Joanna Yosifovna

IPC分类号： C12N9/88 ,  C12R1/00 ,  C12P13/04 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/24

CPC分类号： C12P13/12 ,  C12P7/46 ,  C12P7/625 ,  C12P13/06 ,  C12P13/10 ,  C12P13/14 ,  C12P13/24

摘要： The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.

公开(公告)号：EP1789547B1

公开(公告)日：2010-04-07

申请号：EP05772660.6

申请日：2005-08-10

申请人： Ajinomoto Co., Inc.

发明人： KOZLOV, Yury, Ivanovich ,  CHINEN, Akito, Ajinomoto Co., Inc. ,  IZUI, Hiroshi, Ajinomoto Co., Inc. ,  HARA, Yoshihiko, Ajinomoto Co., Inc. ,  YASUEDA, Hisashi, Ajinomoto Co., Inc. ,  RYBAK, Konstantin Vyacheslavovich ,  SLIVINSKAYA, Ekaterina Aleksandrovna ,  KATASHKINA, Joanna Yosifovna

IPC分类号： C12N9/88 ,  C12R1/00 ,  C12P13/04 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/24

CPC分类号： C12P13/12 ,  C12P7/46 ,  C12P7/625 ,  C12P13/06 ,  C12P13/10 ,  C12P13/14 ,  C12P13/24

公开(公告)号：EP1195431A1

公开(公告)日：2002-04-10

申请号：EP00935595.9

申请日：2000-06-08

申请人： Ajinomoto Co., Inc.

发明人： SUGIMOTO, Masakazu, Ajinomoto Co., Inc. ,  TAKAMURA, Jun, Ajinomoto Co., Inc. ,  IZUI, Hiroshi, Ajinomoto Co., Inc. ,  KIMURA, Eiichiro, Ajinomoto Co., Inc. ,  ITO, Hisao, Ajinomoto Co., Inc. ,  NAKAMATSU, Tsuyoshi, Ajinomoto Co., Inc. ,  KURAHASHI, Osamu, Ajinomoto Co., Inc.

IPC分类号： C12N1/21 ,  C12P13/08 ,  C12N15/54

CPC分类号： C12N9/1205 ,  C12P13/08

摘要： A coryneform bacterium in which an intracellular activity of 6-phosphofructokinase is increased, and which has L-lysine productivity, and a method for producing L-lysine comprising the steps of cultivating the coryneform bacterium, to produce and accumulate L-lysine in a culture, and collecting L-lysine from the culture, as well as a DNA usable in increasing the 6-phosphofructokinase activity.

摘要翻译： 一种增加6-磷酸果糖激酶的细胞内活性并具有L-赖氨酸生产能力的棒杆菌和一种生产L-赖氨酸的方法，该方法包括培养棒状杆菌的步骤，以在培养物中生产和积累L-赖氨酸 ，并从培养物中收集L-赖氨酸，以及可用于增加6-磷酸果糖激酶活性的DNA。