公开(公告)号：EP2576802A1

公开(公告)日：2013-04-10

申请号：EP11727556.0

申请日：2011-06-03

申请人： Ajinomoto Co., Inc.

发明人： FILIPPOV, Dmitriy Vladimirovich ,  LEONOVA, Tatyana Viktorovna ,  VOROSHILOVA, Elvira Borisovna ,  GUSYATINER, Mikhail Markovich ,  MORIYA, Mika ,  NAGAI, Yuri ,  NOGUCHI, Keiko

IPC分类号： C12P13/08 ,  C12P13/10

CPC分类号： C12P13/10 ,  C12N1/20 ,  C12N9/485 ,  C12P13/08 ,  C12Y304/11006 ,  C12Y304/1101 ,  C12Y304/1302

摘要： The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the
Enterobacteriaceae family, particularly a bacterium belonging to the genus
Escherichia or Pantoea , which has been modified to attenuate expression of one or more genes selected from the group consisting of
pepA ,
pepB , and
pepD genes.

公开(公告)号：EP4239070A1

公开(公告)日：2023-09-06

申请号：EP21886136.7

申请日：2021-10-25

申请人： AJINOMOTO CO., INC.

发明人： HIRANO, Seiko ,  INOUE, Kota ,  HAYASHI, Kazuyuki ,  YOKOTA, Kosuke ,  MORIYA, Mika ,  SUZUKI, Tomoko ,  KADOKURA, Yoshitomo ,  NAGAHIKO, Takeshi ,  TASHIRO, Akari

IPC分类号： C12N15/54 ,  C12N15/53 ,  C12N15/55 ,  C12P13/10 ,  C12P13/14 ,  C12P13/24

摘要： Provided is a method of producing an L-amino acid such as L-glutamic acid and the like. An L-amino-acid is produced by cultivating a coryneform bacterium having L-amino acid-producing ability in a culture medium, which has been modified so as to have one or more modifications selected from the group consisting of the following modifications of (A) to (E):
(A) a modification for increasing activity of acetate kinase;
(B) a modification for increasing activity of fructose-1,6-bisphosphatase;
(C) a modification for decreasing activity of pyruvate dehydrogenase;
(D) a modification for decreasing activity of aspartate transaminase; and
(E) a modification for decreasing activity of malic enzyme,
and collecting the L-amino acid from the culture medium and/or the bacterial cells.

公开(公告)号：EP2886651B1

公开(公告)日：2018-08-22

申请号：EP14835548.0

申请日：2014-10-21

申请人： AJINOMOTO CO., INC.

发明人： TOYAZAKI, Miku ,  NOGUCHI, Keiko ,  MORIYA, Mika ,  UEHARA, Yuri

IPC分类号： C12N15/09 ,  C12P13/04

CPC分类号： C12P13/08 ,  C12N15/70 ,  C12P13/04

摘要： A method for producing of an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the acpP-fabF operon is attenuated, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

公开(公告)号：EP2576802B1

公开(公告)日：2014-11-12

申请号：EP11727556.0

申请日：2011-06-03

申请人： Ajinomoto Co., Inc.

发明人： FILIPPOV, Dmitriy Vladimirovich ,  LEONOVA, Tatyana Viktorovna ,  VOROSHILOVA, Elvira Borisovna ,  GUSYATINER, Mikhail Markovich ,  MORIYA, Mika ,  NAGAI, Yuri ,  NOGUCHI, Keiko

IPC分类号： C12P13/08 ,  C12P13/10

CPC分类号： C12P13/10 ,  C12N1/20 ,  C12N9/485 ,  C12P13/08 ,  C12Y304/11006 ,  C12Y304/1101 ,  C12Y304/1302

公开(公告)号：EP3354731A1

公开(公告)日：2018-08-01

申请号：EP16848717.1

申请日：2016-09-26

申请人： Ajinomoto Co., Inc.

发明人： HOSHINO, Yasushi ,  INOUE, Yoshiko ,  MORIYA, Mika ,  MATSUDAIRA, Akiko ,  NISHIO, Yosuke

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N9/00 ,  C12P7/04

CPC分类号： C12P7/04 ,  C12N9/00 ,  C12N15/09 ,  C12N15/74 ,  C12N2330/51 ,  C12Y402/03025 ,  C12Y402/03026

摘要： An object of the present invention is to provide a linalool composition containing linalool, and particularly to provide a composition that contains a high enantiomeric excess of linalool such as R-linalool or S-linalool and has a high content rate of linalool, and to provide a production method therefor. The present invention provides a composition containing linalool, in which a content of linalool in a total content of volatile components in the composition is 60% or more, and an enantiomeric excess of R-linalool or S-linalool being 50% or more, and a production method therefor.

公开(公告)号：EP3354730A1

公开(公告)日：2018-08-01

申请号：EP16848716.3

申请日：2016-09-26

申请人： Ajinomoto Co., Inc.

发明人： HOSHINO, Yasushi ,  MATSUDAIRA, Akiko ,  MORIYA, Mika ,  NITTA, Nobuhisa ,  NISHIO, Yosuke

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N9/00 ,  C12P7/04

CPC分类号： C12P7/04 ,  C12N9/00 ,  C12N9/88 ,  C12N15/09 ,  C12N15/70 ,  C12N15/74 ,  C12P5/007 ,  C12Y402/03025 ,  C12Y402/03026

摘要： An object of the present invention is to provide an efficient method for producing linalool. The present invention provides a method for producing linalool, the method including culturing a microorganism expressing linalool synthase in a culture medium to produce linalool.

公开(公告)号：EP2886651A1

公开(公告)日：2015-06-24

申请号：EP14835548.0

申请日：2014-10-21

申请人： AJINOMOTO CO., INC.

发明人： TOYAZAKI, Miku ,  NOGUCHI, Keiko ,  MORIYA, Mika ,  UEHARA, Yuri

IPC分类号： C12N15/09 ,  C12P13/04

CPC分类号： C12P13/08 ,  C12N15/70 ,  C12P13/04

摘要： A method for producing of an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the acpP-fabF operon is attenuated, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

摘要翻译： 提供了生产L-氨基酸的方法。 L-氨基酸是通过在培养基中培养具有L-氨基酸生产能力的细菌（其经过修饰使得acpP-fabF操纵子被减毒），并收集L-氨基酸， 来自培养基的氨基酸或细菌的细胞。

公开(公告)号：EP1672077B1

公开(公告)日：2015-01-21

申请号：EP04772360.6

申请日：2004-08-27

申请人： Mitsubishi Chemical Corporation ,  Ajinomoto Co., Inc.

发明人： MURASE, Makoto ,  AOYAMA, Ryusuke ,  IKUTA, Miki ,  YAMAGISHI, Kenji ,  MORIYA, Mika ,  NAKAMURA, Jun ,  KOJIMA, Hiroyuki

IPC分类号： C12P7/40 ,  C12N15/09 ,  C12N1/21 ,  C12P7/46

CPC分类号： C12P7/46