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公开(公告)号：EP1200186B1
公开(公告)日：2004-10-20
申请号：EP00927160.2
申请日：2000-05-08
发明人： BERG, Hans , CARLSSON, Mats
CPC分类号： B01J20/286 , B01J20/26 , B01J20/28004 , B01J20/28014 , B01J20/28016 , B01J20/28023 , B01J20/28026 , B01J20/28042 , B01J20/28045 , B01J20/28085 , B01J20/28092 , B01J20/28095 , B01J20/28097 , B01J20/285 , B01J2220/52
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公开(公告)号：EP1115774B1
公开(公告)日：2003-02-26
申请号：EP99951346.8
申请日：1999-09-23
发明人： BERG, Hans , CARLSSON, Mats
CPC分类号： C08J3/16 , C08J2305/00
摘要： The present invention relates to a method for producing porous polysaccharide beads, comprising: (a) mixing a water-based solution of a polysaccharide under stirring with an essentially water-immiscible first organic phase to form an emulsion which separates into two continuous phases; (b) adding a second organic phase comprising an emulsifier and an organic solvent to form a three-phase system; (c) allowing the three-phase system to emulsify; and (d) decreasing the temperature below the gelling point of the polysaccharide, thereby obtaining beads having two sets of pores, said method being characterised in that the emulsifier is a water-insoluble polymer capable of stabilising said three-phase system.
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公开(公告)号：EP1003599B1
公开(公告)日：2005-07-27
申请号：EP98903331.1
申请日：1998-02-03
发明人： BERG, Hans , HANSSON, Hasse , KAGEDAL, Lennart
CPC分类号： B01J20/289 , B01D15/1807 , B01D15/362 , B01D15/363 , B01D15/3804 , B01D2215/021 , B01J20/28014 , B01J20/28026 , B01J20/286 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3274 , B01J39/19 , B01J39/26 , B01J41/20 , B01J47/10 , B01J2220/54 , B01J2220/56
摘要： A method for adsorption of a substance from a liquid sample on a fluidized bead or stirred suspension, in which the beads used comprise a base matrix and exhibit a structure having affinity to the substance, characterized in that the structure is covalently bound to the base matrix via an extender. Populations of beads in which the beads contain a filler incorporated in a base matrix and an extender are also described.
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公开(公告)号：EP1200186A1
公开(公告)日：2002-05-02
申请号：EP00927160.2
申请日：2000-05-08
发明人： BERG, Hans , CARLSSON, Mats
CPC分类号： B01J20/286 , B01J20/26 , B01J20/28004 , B01J20/28014 , B01J20/28016 , B01J20/28023 , B01J20/28026 , B01J20/28042 , B01J20/28045 , B01J20/28085 , B01J20/28092 , B01J20/28095 , B01J20/28097 , B01J20/285 , B01J2220/52
摘要： A matrix comprising: a) a polymeric base matrix comprising macropores (pore system 1) and b) an interior material, possibly porous (pore system 2), retained within the macropores. The matrix is characterized in that there is a continuous free volume between the interior material and the pore walls of the macropores. A method for manufacturing a matrix comprising a base matrix having macropores in which an interior material is located. The method is characterized in comprising the steps: (i) providing a base matrix having macropores; (ii) filling the macropores with a soluble form of the interior material; (iii) transforming the insoluble form to an insoluble form; (iv) shrinking the insoluble form; and (v) irreversibly stabilising the material in its shrinked form. The matrix can be used in separation methods, cell culturing, solid phase synthesis of organic molecules, and in catalytic reactions (such as enzyme reactions) and other uses in which porous support matrices are used.
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公开(公告)号：EP1670829A1
公开(公告)日：2006-06-21
申请号：EP04775508.7
申请日：2004-10-05
发明人： VAN ALSTINE, James, Amersham Biosciences AB , BERG, Hans , BJURLING, Asa, Amersham Biosciences AB
CPC分类号： C07K17/02 , C12N5/0075 , C12N2533/30 , C12N2533/70
摘要： The present invention relates to a microcarrier onto the surface of which a cationic compound has been immobilised via a guanidine group. The microcarrier is capable of attachment of cells, e.g. via charge-based interaction, and is advantageously used as a support in the culture of cells. Said compound may comprise one or two amino acids, such as arginine (Arg) or a dipeptide. The invention also relates to a method of preparing a polycationic microcarrier, which method comprises to immobilise a compound that comprises at least one guanidine group to an epoxide-activated substrate.
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6.发明授权
公开(公告)号：EP0892815B1
公开(公告)日：2004-03-17
申请号：EP97919836.3
申请日：1997-04-07
发明人： BERG, Hans
CPC分类号： B01J20/291 , B01D15/325 , B01D15/327 , B01D15/34 , B01D15/3804 , B01D15/3828 , B01J20/262 , B01J20/267 , B01J20/285 , B01J2220/54 , C08B37/0039
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