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1.发明授权BENZO(b)THIEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权苯并（b）中硫杂七环-1,1-二氧化物的衍生物，用于生产药物含有它们及其用途
公开(公告)号：EP1086092B1
公开(公告)日：2002-11-13
申请号：EP99927784.1
申请日：1999-05-28
IPC分类号： C07D337/08 , C07K5/068 , A61K31/38
CPC分类号： C07D337/08 , A61K38/00 , C07K5/06086 , C08G65/329 , Y02P20/55
摘要： The invention relates to substituted benzo(b)thiepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention relates to compounds of formula (I), wherein R?1, R2, R3, R4, R5¿ and Z have the cited descriptions, to the physiologically compatible salts, to physiologically functional derivatives, and to a method for the production thereof. The compounds are suited, for example, as hypolipidemic agents.
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2.发明公开
公开(公告)号：EP1117676A1
公开(公告)日：2001-07-25
申请号：EP99947385.3
申请日：1999-09-18
IPC分类号： C07J43/00 , C07K5/065 , A61K31/575
摘要： The invention relates to substituted propanolamine derivatives and their pharmaceutically acceptable salts and physiologically functional derivatives. The invention relates to compounds of formula (I), wherein the radicals have the defined meanings, as well as their physiologically acceptable salts, physiologically acceptable derivatives and methods for their production. The compounds are suitable, for example, as hypolipidemic agents.
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3.发明授权SUBSTITUIERTE PHENYL-ALKENOYLGUANIDINE, VERFAHREN ZU IHRER HERSTELLUNG, IHRE VERWENDUNG ALS MEDIKAMENTE ODER DIAGNOSTIKA SOWIE SIE ENTHALTENDE MEDIKAMENTE 有权取代苯基ALKENOYLGUANIDINE，PROCESS FOR THEIR，它们的使用药物或诊断和含有药物
公开(公告)号：EP1124841B1
公开(公告)日：2003-04-02
申请号：EP99949001.4
申请日：1999-10-15
发明人： WEICHERT, Andreas , ENHSEN, Alfons , FALK, Eugen , JANSEN, Hans-Willi , KRAMER, Werner , SCHWARK, Jan-Robert , LANG, Hans, Jochen
IPC分类号： C07J41/00 , A61K31/575 , C07J9/00
CPC分类号： C07J41/0055 , C07J9/005 , C07J41/0061
摘要： The invention relates to substituted phenyl alkenoyl guanidines, the pharmaceutically acceptable salts thereof, and physiolgically functional derivatives. Compounds of formula (I) are disclosed, wherein the radicals have the meanings thus cited. Also disclosed are the physiologically acceptable salts thereof, physiologically functional derivatives and methods for the production thereof. The inventive compounds are, for instance, suitable for use as medicaments for the prophylaxis or treatment of gall stones.
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4.发明公开CARBOXYALKOXY-SUBSTITUIERTE ACYL-CARBOXYPHENYL-HARNSTOFFDERIVATE, VERFAHREN ZU IHRE HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权羧基烷氧基 - 取代的酰基羧基苯基脲衍生物，进程中为其及其作为药物
公开(公告)号：EP1556339A2
公开(公告)日：2005-07-27
申请号：EP03757879.6
申请日：2003-09-22
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , KLABUNDE, Thomas , BURGER, Hans-Joerg , HERLING, Andreas , WENDT, Karl-Ulrich , VON REODERN, Erich , SCHOENAFINGER, Karl , ENHSEN, Alfons
IPC分类号： C07C275/00
CPC分类号： C07C275/54
摘要： The invention concerns carboxyalkoxy-substituted acyl-carboxyphenyl-urea derivatives of formula (I) wherein the groups are such as defined in the description and their physiologically acceptable salts and their physiologically functional derivatives. The invention also concerns a method for producing said compounds which can be used for example for treating type II diabetes.
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5.发明公开ACYL-3-CARBOXYPHENYL-HARNSTOFFDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG 有权酰基3-羧基苯基脲衍生物，用于生产及其用途
公开(公告)号：EP1497263A1
公开(公告)日：2005-01-19
申请号：EP03745772.8
申请日：2003-03-28
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , SCHOENAFINGER, Karl , KLABUNDE, Thomas , BURGER, Hans-Joerg , HERLING, Andreas , WENDT, Karl-Ulrich , VON ROEDERN, Erich , ENHSEN, Alfons
IPC分类号： C07C275/54 , A61K31/192 , A61P3/10
CPC分类号： C07C275/54
摘要： The invention relates to acyl-3-carboxyphenylurea derivatives, physiologically-acceptable salts, physiologically-functional derivatives thereof and compounds of formula (I), where the groups have the given meanings, the physiologically-acceptable salts and method for production thereof. The compounds are suitable as, for example, antidiabetics.
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6.发明授权
公开(公告)号：EP1086113B1
公开(公告)日：2004-02-11
申请号：EP99927802.1
申请日：1999-05-29
IPC分类号： C07H15/26 , C07D337/08 , A61K31/70 , A61K31/38
CPC分类号： C07D337/08 , A61K38/00 , C07K5/06086 , C08G65/329 , Y02P20/55
摘要： The invention relates to benzothiepine-1,1-dioxide derivatives and their acid addition salts, i.e. compounds of formula (I) wherein R?1, R2, R3, R4, R5¿ and Z have the meanings given in the description and their physiologically compatible salts and physiologically functional derivatives. The invention also relates to a method for producing said compounds, which are suitable for use as e.g. hypolipidaemics.
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7.发明公开BENZO(b)THIEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权苯并（b）中硫杂七环-1,1-二氧化物的衍生物，用于生产药物含有它们及其用途
公开(公告)号：EP1086092A1
公开(公告)日：2001-03-28
申请号：EP99927784.1
申请日：1999-05-28
IPC分类号： C07D337/08 , C07K5/068 , A61K31/38
CPC分类号： C07D337/08 , A61K38/00 , C07K5/06086 , C08G65/329 , Y02P20/55
摘要： The invention relates to substituted benzo(b)thiepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention relates to compounds of formula (I), wherein R?1, R2, R3, R4, R5¿ and Z have the cited descriptions, to the physiologically compatible salts, to physiologically functional derivatives, and to a method for the production thereof. The compounds are suited, for example, as hypolipidemic agents.
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8.发明公开ACYL-4-CARBOXY-PHENYL-HARNSTOFFDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG 有权酰基4-羧基苯基脲衍生物，用于生产及其用途
公开(公告)号：EP1497262A1
公开(公告)日：2005-01-19
申请号：EP03712111.8
申请日：2003-03-28
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , SCHOENAFINGER, Karl , KLABUNDE, Thomas , BURGER, Hans-Joerg , HERLING, Andreas , WENDT, Karl-Urlich , VON ROEDERN, Erich , ENHSEN, Alfons , RIEKE-ZAPP, Joerg
IPC分类号： C07C275/54 , C07D295/12 , A61K31/17 , A61P7/12
CPC分类号： C07D295/155 , C07C275/54
摘要： The invention relates to acyl-4-carboxyphenylurea derivatives, the physiologically-acceptable salts, physiologically-functional derivatives thereof and compounds of formula (I), where the groups have the given meanings, the physiologically acceptable salts and method for production thereof. Said compounds are suitable, for example, as anti-diabetics.
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9.发明授权
公开(公告)号：EP1117676B1
公开(公告)日：2004-08-18
申请号：EP99947385.3
申请日：1999-09-18
IPC分类号： C07J43/00 , C07K5/065 , A61K31/575
摘要： The invention relates to substituted propanolamine derivatives and their pharmaceutically acceptable salts and physiologically functional derivatives. The invention relates to compounds of formula (I), wherein the radicals have the defined meanings, as well as their physiologically acceptable salts, physiologically acceptable derivatives and methods for their production. The compounds are suitable, for example, as hypolipidemic agents.
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10.发明授权SUBSTITUIERTE 1,3-DIARYL-2-PYRIDIN-2-YL-3-(PYRIDIN-2-YLAMINO)-PROPANOLDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权取代的1,3-二芳基-2-吡啶-2-基-3-（吡啶-2-基氨基）-PROPANOLDERIVATE，PROCESS FOR PRODUCING药物含有它们及其用途
公开(公告)号：EP1117642B1
公开(公告)日：2004-05-26
申请号：EP99948791.1
申请日：1999-09-18
IPC分类号： C07D213/74 , C07D401/14 , C07D409/14 , C07D405/14 , C07D417/14 , C07D471/04 , C07D473/04 , C07D413/14 , A61K31/4427
CPC分类号： C07D213/74 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D473/04
摘要： The invention relates to substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives and their pharmaceutically acceptable salts and physiologically functional derivatives. The invention describes substituted 1,3-diaryl-2-yl-3-(pyridine-2-ylamino)-propanol derivatives of formula (I), wherein the radicals have the defined meanings, as well as their physiologically acceptable salts, and methods for their production. The compounds are suitable, e.g. as hypolipidemic agents.
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