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1.发明公开ANIMAUX TRANSGENIQUES PRESENTANT LES TROUBLES MAJEURS LIES A LA MALADIE D'ALZHEIMER 有权与阿尔茨海默病相关的GO相关的严重病理状态转基因动物
公开(公告)号：EP1670309A1
公开(公告)日：2006-06-21
申请号：EP04787459.9
申请日：2004-09-27
申请人： Aventis Pharma S.A.
发明人： CASAS LOUZAO, Caty , BENOIT, Patrick , PRADIER, Laurent , TREMP, Gunter , ITIER, Jean-Michel , BLANCHARD-BREGEON, Véronique
IPC分类号： A01K67/027 , C07K14/47 , G01N33/50 , C12N15/90 , C12N5/10 , C12N15/12 , C12N15/63 , C12Q1/02
CPC分类号： C07K14/4711 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/072 , A01K2227/105 , A01K2227/107 , A01K2267/0312 , C12N15/8509 , C12N2517/02
摘要： The invention relates to non-human transgenic animals with serious disorders related to Alzheimer's disease. The animals can be used for the discovery of compounds for the treatment of Alzheimer's disease.
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2.发明授权ASSOCIATIONS DE RILUZOLE ET DE LEVODOPA POUR LE TRAITEMENT DE LA MALADIE DE PARKINSON 有权利鲁唑和左旋多巴的组合来治疗帕金森病
公开(公告)号：EP1071422B1
公开(公告)日：2008-02-20
申请号：EP99915809.0
申请日：1999-04-22
申请人： Aventis Pharma S.A.
发明人： BLANCHARD-BREGEON, Véronique , IMPERATO, Assunta , MOUSSAOUI, Saliha , OBINU, Marie-Carmen , REIBAUD, Michel
IPC分类号： A61K31/428 , A61P25/16 , A61K31/198
CPC分类号： A61K31/425 , A61K31/195 , A61K31/215 , A61K45/06 , A61K31/175 , A61K2300/00
摘要： The invention concerns a combination of levodopa and riluzole or a pharmaceutically acceptable salt of said compound and the use of said combination for treating Parkinson disease.
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3.发明公开NOUVEAU MODELE ANIMAL DE LA MALADIE D'ALZHEIMER PRESENTANT A LA FOIS DES PLAQUES AMYLOIDES ET DES DYSFONCTIONNEMENTS MITOCHONDRIAUX 审中-公开动物模型的建立阿尔茨海默氏症的疾病什么淀粉样蛋白沉积和线粒体疾病HAVING
公开(公告)号：EP1235482A1
公开(公告)日：2002-09-04
申请号：EP00962636.7
申请日：2000-09-14
申请人： Aventis Pharma S.A.
发明人： MOUSSAOUI-MRABET, Saliha , BLANCHARD-BREGEON, Véronique , IMPERATO, Assunta , BONICI, Bruno , TREMP, Gunter , CZECH, Christian
IPC分类号： A01K67/027 , C07K14/47 , A61K49/00 , C12N5/10 , G01N33/50
CPC分类号： A01K67/027 , A61K49/00 , C07K14/47 , C12N5/10 , G01N33/50
摘要： The invention concerns the field of transgenic animal models and more particularly, animal models of Alzheimer disease. The invention relates to a novel animal model of Alzheimer disease having both amyloid plaques and mitochondrial dysfunctions.
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4.发明授权ANIMAUX TRANSGENIQUES PRESENTANT LES TROUBLES MAJEURS LIES A LA MALADIE D'ALZHEIMER 有权与阿尔茨海默病相关的GO相关的严重病理状态转基因动物
公开(公告)号：EP1670309B1
公开(公告)日：2010-06-23
申请号：EP04787459.9
申请日：2004-09-27
申请人： Aventis Pharma S.A.
发明人： CASAS LOUZAO, Caty , BENOIT, Patrick , PRADIER, Laurent , TREMP, Gunter , ITIER, Jean-Michel , BLANCHARD-BREGEON, Véronique
IPC分类号： A01K67/027 , C07K14/47 , G01N33/50 , C12N15/90 , C12N5/10 , C12N15/12 , C12N15/63 , C12Q1/02
CPC分类号： C07K14/4711 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/072 , A01K2227/105 , A01K2227/107 , A01K2267/0312 , C12N15/8509 , C12N2517/02
摘要： The invention relates to non-human transgenic animals with serious disorders related to Alzheimer's disease. The animals can be used for the discovery of compounds for the treatment of Alzheimer's disease.
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5.发明公开ASSOCIATIONS DE RILUZOLE ET DE LEVODOPA POUR LE TRAITEMENT DE LA MALADIE DE PARKINSON 有权利鲁唑和左旋多巴的组合来治疗帕金森病
公开(公告)号：EP1071422A1
公开(公告)日：2001-01-31
申请号：EP99915809.0
申请日：1999-04-22
申请人： Aventis Pharma S.A.
发明人： BLANCHARD-BREGEON, Véronique , IMPERATO, Assunta , MOUSSAOUI, Saliha , OBINU, Marie-Carmen , REIBAUD, Michel
IPC分类号： A61K31/425
CPC分类号： A61K31/425 , A61K31/195 , A61K31/215 , A61K45/06 , A61K31/175 , A61K2300/00
摘要： The invention concerns a combination of levodopa and riluzole or a pharmaceutically acceptable salt of said compound and the use of said combination for treating Parkinson disease.
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