-
1.发明公开PROCEDE DE FABRICATION DE PRODUIT DE TYPE THIAZOLO [3,4,5-DE] [4,1] BENZOTHIAZEPINE 有权制造方法的产品噻唑并[3,4,5-降] [4,1]苯并硫氮杂TYPE
公开(公告)号：EP1694658A1
公开(公告)日：2006-08-30
申请号：EP04805651.9
申请日：2004-12-07
申请人： Aventis Pharma S.A.
IPC分类号： C07D281/10 , C07C271/28
CPC分类号： C07D513/06 , C07C271/28
摘要： The invention relates to novel methods of preparing a thiazolo[3,4,5-de][4,1]benzothiazepine-type compound and, in particular, methanesulfonate of 6,6-dioxide of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de][4,1]benzothiazepine and of (R,S) 6-oxide of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de][4,1]benzothiazepine, as well as the enantiomers and the pharmaceutically-acceptable salts thereof.
-
2.发明公开
公开(公告)号：EP1611127A2
公开(公告)日：2006-01-04
申请号：EP04742385.0
申请日：2004-03-29
申请人： Aventis Pharma S.A.
发明人： BIGOT, Antony , CHEVE, Michel , EL AHMAD, Youssef , MALLERON, Jean-Luc , MARTIN, Jean-Paul , MIGNANI, Serge , PANTEL, Guy , RONAN, Baptiste , TABART, Michel , VIVIANI, Fabrice
IPC分类号： C07D409/14 , C07D401/06 , C07D413/06
CPC分类号： C07D401/06 , C07D409/14 , C07D413/06
摘要： The invention concerns 4-substituted quinoline derivatives active as antimicrobial agents, of general formula (I), wherein: X1, X2, X3, X4 and X5 respectively represent >C-R'1 to >C-R'5, or not more than one represents N; Y represents CHR, CO, CROH, CRNH2, CRF or CF2, R being hydrogen or alkyl; m is 1, 2, or 3 and n is 0, 1 or 2; Z is CH2 or Z represents O, S, SO, SO2 and, in that case, n is equal to 2; R2 represents -CO2R, -CH2CO2R, -CH2-CH2CO2R, -CH2OH or -CH2-CH2OH, R being as defined above; R3 represents phenyl, heteroaryl or alk-R°3, wherein alk is an alkyl and R°3 represents various groups, optionally oxygenated, sulphured or aminated, in their enantiomeric or diastereoisomeric forms or mixtures thereof, and optionally in their syn or anti forms or mixtures thereof, as well as their salts.
-
公开(公告)号：EP0948483B1
公开(公告)日：2002-03-13
申请号：EP97953000.3
申请日：1997-12-23
申请人： Aventis Pharma S.A.
发明人： BOURZAT, Jean-Dominique , COMMERCON, Alain , DEREU, Norbert , MAILLIET, Patrick , SOUNIGO-THOMPSON, Fabienne , MARTIN, Jean-Paul , CAPET, Marc , CHEVE, Michel
IPC分类号： C07D209/72 , A61K31/40 , C07D401/12 , C07D405/04 , C07D405/14 , C07D409/14 , C07D409/04 , C07D403/04 , C07D409/12
CPC分类号： C07D401/12 , C07D209/72 , C07D403/04 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14
-
4.发明授权DERIVES DE LA QUINOLYL PROPYL PIPERIDINE ET LEUR UTILISATION EN TANT QUE ANTIBACTERIENS 有权CHINOLINPROPYL哌啶衍生物及其作为抗菌剂的用途
公开(公告)号：EP1218370B1
公开(公告)日：2004-12-08
申请号：EP00962637.5
申请日：2000-09-14
申请人： Aventis Pharma S.A.
发明人： MALLERON, Jean-Luc , TABART, Michel , CARRY, Jean-Christophe , EVERS, Michel , EL AHMAD, Youssef , MIGNANI, Serge , VIVIANI, Fabrice , CHEVE, Michel
IPC分类号： C07D401/06 , A61K31/47 , A61P31/04 , C07D409/14 , C07D417/14 , C07D401/14
CPC分类号： C07D409/14 , C07D401/06 , C07D401/14 , C07D417/14
-
5.发明授权PROCEDE DE FABRICATION DE PRODUIT DE TYPE THIAZOLO [3,4,5-DE] [4,1] BENZOTHIAZEPINE 有权制造方法的产品噻唑并[3,4,5-降] [4,1]苯并硫氮杂TYPE
公开(公告)号：EP1694658B1
公开(公告)日：2009-02-25
申请号：EP04805651.9
申请日：2004-12-07
申请人： Aventis Pharma S.A.
IPC分类号： C07D281/10 , C07C271/28
CPC分类号： C07D513/06 , C07C271/28
摘要： The invention relates to novel methods of preparing a thiazolo[3,4,5-de][4,1]benzothiazepine-type compound and, in particular, methanesulfonate of 6,6-dioxide of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de][4,1]benzothiazepine and of (R,S) 6-oxide of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de][4,1]benzothiazepine, as well as the enantiomers and the pharmaceutically-acceptable salts thereof.
-
-
-
-
搜索结果
5 条记录 (耗时 0.02 秒)
