公开(公告)号：EP0912544A1

公开(公告)日：1999-05-06

申请号：EP96927534.0

申请日：1996-07-09

申请人： BASF AKTIENGESELLSCHAFT

发明人： FRANK, Jürgen ,  MELDER, Johann-Peter ,  MERGER, Franz ,  WITZEL, Tom

IPC分类号： C07D319

CPC分类号： C07D319/06 ,  C07D319/08 ,  Y02P20/584

摘要： The invention concerns a process for preparing 2-substituted but-2-ene-1,4-dial-acetals of general formula (I) in which the substituents R1 to R4 stand for hydrogen or C¿1?-C6 aliphatic groups and R?2 and R3 or R1 and R2¿ in each case are common members of an aliphatic 4- to 7-member ring which can contain a heteroatom, and in which R5 designates a C¿1?-C12 alkyl, alkenyl or alkinyl group, which can be substituted by cycloaliphatic, aromatic or heterocyclic groups or by hydroxy, ether, thioether, acyl, alkylamino, carboxy or carbalkoxy groups, an optionally substituted aryl group or an alkoxy, alkylthio or acyloxy group. According to the invention: a) glyoxal is reacted with a 1,3-propane diol of general formula (II) in an aqueous solution in the presence of an acid to form a monoacetal of general formula (III), the reaction solution is neutralized and optionally the volatile components which are lighter than the monoacetal (III) are distilled off; b) the resultant monoacetal (III) is reacted with an aldehyde R?5¿-CHO in the presence of between 0.01 and 10 mol %, relative to glyoxal, of a catalyst mixture consisting of a secondary amine and an acid to form an aldol of general formula (IV), and optionally the volatile components which are lighter than the aldol (IV) are distilled off; and c) the aldol (IV) is dehydrogenated in the presence of a dehydrating agent to form product (I). The invention also concerns novel hemiacetals of glyoxalmonoacetals.

公开(公告)号：EP0759896A1

公开(公告)日：1997-03-05

申请号：EP95920071.0

申请日：1995-05-19

申请人： BASF AKTIENGESELLSCHAFT

发明人： BRUDERMÜLLER, Martin ,  IRGANG, Matthias ,  SCHMIDT-RADDE, Martin ,  MERGER, Franz ,  WITZEL, Tom ,  KRATZ, Detlef ,  DANZ, Eckehard ,  WITTWER, Arnold ,  HESSE, Michael ,  SAUERWALD, Manfred ,  FREIRE ERDBRÜGGER, Cristina

IPC分类号： B01J23 ,  B01J21 ,  C07B61 ,  C07C29 ,  C07C31

CPC分类号： C07C29/145 ,  B01J21/08 ,  B01J23/72 ,  B01J23/868 ,  C07C29/141 ,  C07C29/175 ,  C07C2601/08 ,  C07C2603/68 ,  C07C31/205 ,  C07C31/20 ,  C07C31/12 ,  C07C31/125 ,  C07C31/278 ,  C07C31/274

摘要： An alcohol preparation process is disclosed by catalytic hydrogenation of the corresponding carbonyl compounds at high temperature and pressure in liquid phase. A catalyst is used that contains copper on a SiO2-containing substrate in the presence or absence of one or several elements selected among magnesium, barium, zinc or chromium.

摘要翻译： 醇通过在液相中在升高的温度和超大气压下通过催化氢化制备，其中所用催化剂在含SiO 2的载体上含有铜，在存在或不存在一种或多种 元素镁，钡，锌和铬。

公开(公告)号：EP0912544B1

公开(公告)日：2004-10-06

申请号：EP96927534.6

申请日：1996-07-09

申请人： BASF AKTIENGESELLSCHAFT

发明人： FRANK, Jürgen ,  MELDER, Johann-Peter ,  MERGER, Franz ,  WITZEL, Tom

IPC分类号： C07D319/06 ,  C07D319/08

CPC分类号： C07D319/06 ,  C07D319/08 ,  Y02P20/584

摘要： The invention concerns a process for preparing 2-substituted but-2-ene-1,4-dial-acetals of general formula (I) in which the substituents R to R stand for hydrogen or C1-C6 aliphatic groups and R and R or R and R in each case are common members of an aliphatic 4- to 7-member ring which can contain a heteroatom, and in which R designates a C1-C12 alkyl, alkenyl or alkinyl group, which can be substituted by cycloaliphatic, aromatic or heterocyclic groups or by hydroxy, ether, thioether, acyl, alkylamino, carboxy or carbalkoxy groups, an optionally substituted aryl group or an alkoxy, alkylthio or acyloxy group. According to the invention: a) glyoxal is reacted with a 1,3-propane diol of general formula (II) in an aqueous solution in the presence of an acid to form a monoacetal of general formula (III), the reaction solution is neutralized and optionally the volatile components which are lighter than the monoacetal (III) are distilled off; b) the resultant monoacetal (III) is reacted with an aldehyde R -CHO in the presence of between 0.01 and 10 mol %, relative to glyoxal, of a catalyst mixture consisting of a secondary amine and an acid to form an aldol of general formula (IV), and optionally the volatile components which are lighter than the aldol (IV) are distilled off; and c) the aldol (IV) is dehydrogenated in the presence of a dehydrating agent to form product (I). The invention also concerns novel hemiacetals of glyoxalmonoacetals.

公开(公告)号：EP0759896B1

公开(公告)日：2002-01-30

申请号：EP95920071.8

申请日：1995-05-19

申请人： BASF AKTIENGESELLSCHAFT

发明人： BRUDERMÜLLER, Martin ,  IRGANG, Matthias ,  SCHMIDT-RADDE, Martin ,  MERGER, Franz ,  WITZEL, Tom ,  KRATZ, Detlef ,  DANZ, Eckehard ,  WITTWER, Arnold ,  HESSE, Michael ,  SAUERWALD, Manfred ,  FREIRE ERDBRÜGGER, Cristina

IPC分类号： C07C29/141 ,  C07C29/145 ,  C07C31/20 ,  C07C31/12 ,  C07C31/27 ,  C07C31/125

CPC分类号： C07C29/145 ,  B01J21/08 ,  B01J23/72 ,  B01J23/868 ,  C07C29/141 ,  C07C29/175 ,  C07C2601/08 ,  C07C2603/68 ,  C07C31/205 ,  C07C31/20 ,  C07C31/12 ,  C07C31/125 ,  C07C31/278 ,  C07C31/274

摘要： An alcohol preparation process is disclosed by catalytic hydrogenation of the corresponding carbonyl compounds at high temperature and pressure in liquid phase. A catalyst is used that contains copper on a SiO2-containing substrate in the presence or absence of one or several elements selected among magnesium, barium, zinc or chromium.

摘要翻译： 醇通过在液相中在升高的温度和超大气压下通过催化氢化制备，其中所用催化剂在含SiO 2的载体上含有铜，在存在或不存在一种或多种 元素镁，钡，锌和铬。