公开(公告)号：EP0968169B1

公开(公告)日：2002-05-22

申请号：EP98906939.8

申请日：1998-02-09

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  EVA, Ronald, R. ,  FRANKE, Dirk ,  JONES, Simon, A. ,  MATTMANN, Wolfgang ,  MUNZINGER, Manfred

IPC分类号： C07C65/24

CPC分类号： C07C65/24 ,  C07C51/02

摘要： The invention relates to a method for isolating 3-[2-chloro-4-(trifluoromethyl)-phenoxy]-benzoic acid of the formula (I) from an aqueous solution of its metallic salt, by a) reacting the metallic salt of the 3-[2-chloro-4-(trifluoromethyl)-phenoxy]-benzoic acid with an organic or inorganic acid; b) heating the reaction mixture until a liquid two-phase system has formed comprising an organic and aqueous phase; and c) separating the organic phase from the aqueous phase.

公开(公告)号：EP1320527A1

公开(公告)日：2003-06-25

申请号：EP01983513.1

申请日：2001-09-28

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  FRETSCHNER, Erich

IPC分类号： C07D231/16 ,  C07D231/14 ,  C07D231/20

CPC分类号： C07D231/16 ,  C07D231/22

摘要： The invention relates to a method for producing 1-substituted 5-chloro-4-methyl pyrazoles of general formula (I) wherein R has the designated cited in claim 1. Said method reacts 4-methyl pyrazole of general formula (II) with chlorine, separating the mixture obtained from mono and dichlorinated products, by means of distillation subsequently dehalogenizing the dichlorinated compound to obtain compound II and re-introduction into the reaction with chlorine.

公开(公告)号：EP1198466B1

公开(公告)日：2003-04-02

申请号：EP00956244.8

申请日：2000-07-21

申请人： BASF AKTIENGESELLSCHAFT

发明人： MÜLLER, Ulrich ,  MERKLE, Hans, Rupert

IPC分类号： C07F9/38

CPC分类号： C07F9/3813

摘要： The invention relates to a method of producing N-phosphonomethylglycine or a salt thereof by contacting phosphonomethyliminodiacetic acid or a salt thereof with at least one oxygenous oxidant in the presence of a heterogeneous catalyst, said catalyst containing at least one silicate.

公开(公告)号：EP1165520A1

公开(公告)日：2002-01-02

申请号：EP00912664.0

申请日：2000-03-30

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  HERBIG, Klaus ,  FRETSCHNER, Erich ,  FRÖHLICH, Helmut

IPC分类号： C07D237/22

CPC分类号： C07D237/22

摘要： The invention relates to a method for producing 4-amino-5-chloro-1-phenyl pyridazinone-(6) by reacting 4,5-dichloro-1-phenyl pyridazinone-(6) with aqueous ammonia in the presence of a catalyst. According to the invention, a catalyst is used which is soluble in the aqueous alkaline reaction medium but which is, however, essentially insoluble in the reaction mixture that is acidically regulated after the 4-amino-5-chloro-1-phenyl pyridazinone-(6) has been removed. The inventive method makes it possible, in a simple manner, to recover and reuse the catalyst.

公开(公告)号：EP1005462A1

公开(公告)日：2000-06-07

申请号：EP98942624.2

申请日：1998-07-25

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  WÖRZ, Otto ,  FRETSCHNER, Erich ,  HANSEN, Hanspeter ,  MÜLLER, Albrecht ,  BENZ, Kurt

IPC分类号： C07D285/16

CPC分类号： C07D285/16

摘要： The invention relates to a method for the production of 3-isopropyl-1H-2,1,3-benzothiazine-4(3H)-one-2,2-dioxide (I) or its salt. The method is characterized in that anthranilic acid isopropylamide (II) is reacted simultaneously with sulphur trioxide or chlorosulphonic acid in the presence of an organic base, or with sulphur trioxide adducts on organic bases, and phosphoroxychloride at 50 °C until reflux temperature, and then optionally transformed into their salts.

公开(公告)号：EP0799177B1

公开(公告)日：2000-04-05

申请号：EP95941709.8

申请日：1995-12-13

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  BRENNER, Karl, Siegfried ,  FRETSCHNER, Erich ,  SCHÖNHERR, Michael ,  VAN GASTEL, Anne

IPC分类号： C07C51/41 ,  C07C59/68 ,  C07C59/70

CPC分类号： C07C51/412 ,  A01N39/02 ,  A01N39/04 ,  A01N43/88 ,  A01N37/40 ,  A01N25/12 ,  A01N2300/00

摘要： A process is disclosed for preparing solid, free-flowing water-soluble salts of aryloxy-C1-C4-alkane carboxylic acids. Aryloxy-C1-C4-alkane carboxylic acids are reacted with a salt-forming base. Salts are formed in the melt in the presence or absence of an entrainer suitable for causing azeotropic water separation or in a solution in the presence of an entrainer suitable for causing azeotropic water separation. The entrainer is removed from the reaction mixture during or after the reaction and the solid salts are then isolated in the usual manner.

公开(公告)号：EP0968169A1

公开(公告)日：2000-01-05

申请号：EP98906939.8

申请日：1998-02-09

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  EVA, Ronald, R. ,  FRANKE, Dirk ,  JONES, Simon, A. ,  MATTMANN, Wolfgang ,  MUNZINGER, Manfred

IPC分类号： C07C65/24

CPC分类号： C07C65/24 ,  C07C51/02

摘要： The invention relates to a method for isolating 3-[2-chloro-4-(trifluoromethyl)-phenoxy]-benzoic acid of the formula (I) from an aqueous solution of its metallic salt, by a) reacting the metallic salt of the 3-[2-chloro-4-(trifluoromethyl)-phenoxy]-benzoic acid with an organic or inorganic acid; b) heating the reaction mixture until a liquid two-phase system has formed comprising an organic and aqueous phase; and c) separating the organic phase from the aqueous phase.

公开(公告)号：EP0804405B1

公开(公告)日：1999-04-07

申请号：EP96900560.2

申请日：1996-01-04

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  FRETSCHNER, Erich ,  HANSEN, Hanspeter ,  ZIPPERER, Bernhard

IPC分类号： C07C53/19 ,  C07B57/00 ,  C07C51/09 ,  C07C51/487

CPC分类号： C07B57/00 ,  C07C51/09 ,  C07C53/19

摘要： The present invention relates to a process for producing optically active 2-halogen propionic acids in which the corresponding optically active 2-halogen propionic acid alkyl ester is reacted at high temperature with a carboxylic acid in a transacylation reaction to form the optically active 2-halogen propionic acid and the carboxylic acid alkyl ester and the optically active 2-halogen propionic acid is separated from the reaction mixture. The optically active products of the process are important intermediate products for the production of plant protection agents and pharmaceuticals.

公开(公告)号：EP0809638A2

公开(公告)日：1997-12-03

申请号：EP96902969.0

申请日：1996-02-01

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  DUREIN, Alfons ,  HANSEN, Hanspeter ,  JÄGER, Karl-Friedrich

IPC分类号： A01N43 ,  C07D285

CPC分类号： C07D285/16

摘要： A process for producing salts of 3-isopropyl-2,1,3-benzothiadiazine-4-on-2,2-dioxide of general formula (I) (R1-R4 = H, lower alkyl, lower hydroxyalkyl) by reacting bentazone (IIa) in an organic solvent with an amine (IIIa), reacting bentazone (IIa) in an organic solvent virtually immiscible with water with an amine (IIIa) or an ammonium salt (IIIb) and taking salt (I) up in water or reacting bentazone (IIa) with an ammonium salt (IIIb) or sodium bentazone (IIb) with an ammonium salt (IIIc) in water.

公开(公告)号：EP0906264A1

公开(公告)日：1999-04-07

申请号：EP97925047.0

申请日：1997-06-05

申请人： BASF AKTIENGESELLSCHAFT

发明人： MERKLE, Hans, Rupert ,  FRETSCHNER, Erich ,  HOFMANN, Jürgen ,  JÄGER, Karl-Friedrich ,  DIENER, Ralph ,  HÄRTL, Axel, Paul ,  SCHÖNHERR, Michael

IPC分类号： C07C59 ,  A01N25 ,  A01N39 ,  C07C51

CPC分类号： C07C51/412 ,  C07C59/68

摘要： A process for the production of alkaline metal salts and earth alkali metal salts of aryloxy-C1-C4-alkane carboxylic acids by reacting the basic aryloxy-C1-C4-alkane carboxylic acids with alkaline metal bases or earth alkali metal bases in the melt, by extruding a mixture of the aryloxy-C1-C4-alkane carboxylic acid and an at least stoichiometric quantity of an alkaline metal base or an earth alkali metal base, which are partially or completely converted in the reaction conditions into volatile substances. The invention also concerns the extrudates thus obtainable and the use of the extrudates which contain an aryloxy-C1-C4-alkane carboxylic acid with herbicidal action to combat undesired plant growth.