公开(公告)号：EP2170358A2

公开(公告)日：2010-04-07

申请号：EP08786013.6

申请日：2008-07-09

申请人： BASF Beauty Care Solutions France SAS

发明人： ABDUL-MALAK, Nabil ,  ALTOBELLI, Cécile ,  PERRIER, Eric

IPC分类号： A61K36/00 ,  A61K31/136 ,  A61K31/192 ,  A61K31/353 ,  A61K31/404 ,  A61K31/407 ,  A61K31/60 ,  A61K8/35 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/97 ,  A61P3/10 ,  A61P17/00 ,  A61Q19/08 ,  A23L1/29 ,  G01N33/68

CPC分类号： G01N33/6803 ,  A61K8/347 ,  A61K8/365 ,  A61K8/368 ,  A61K8/415 ,  A61K8/492 ,  A61K8/498 ,  A61K8/97 ,  A61K31/05 ,  A61K31/136 ,  A61K31/185 ,  A61K31/192 ,  A61K31/353 ,  A61K31/404 ,  A61K31/407 ,  A61K31/60 ,  A61K36/00 ,  A61Q19/08 ,  A61K2300/00

摘要： The invention relates to the use, as active ingredient, of at least one substance that promotes AGE deglycation, for the preparation of a composition, especially for limiting the presence of AGEs in a tissue. The invention relates in particular to the use of such a substance for the preparation of a composition for use in preventing and/or combating the decrease in flexibility and/or plasticity and/or elasticity and/or functionality of a tissue, and/or in preventing and/or combating ageing of a tissue, by promoting AGE deglycation in the tissue, wherein said tissue is preferably the skin, or the tissue wall of a blood vessel or of an organ.

公开(公告)号：EP2170307A2

公开(公告)日：2010-04-07

申请号：EP08786012.8

申请日：2008-07-09

申请人： BASF Beauty Care Solutions France SAS

发明人： ABDUL-MALAK, Nabil ,  ALTOBELLI, Cécile ,  PERRIER, Eric

IPC分类号： A61K31/05 ,  A61K31/122 ,  A61K31/353 ,  A61K31/7004 ,  A61K36/00 ,  A61K8/97 ,  A61K8/41 ,  A61K8/35 ,  A61K8/34 ,  A61P17/00 ,  A61P3/10 ,  A61Q19/08 ,  A23L1/29

CPC分类号： A61Q19/08 ,  A23L33/105 ,  A61K8/347 ,  A61K8/35 ,  A61K8/355 ,  A61K8/411 ,  A61K8/415 ,  A61K8/498 ,  A61K8/97 ,  A61K31/05 ,  A61K31/122 ,  A61K31/353 ,  A61K31/7004 ,  A61K36/15 ,  A61K36/45 ,  A61K36/48 ,  A61K36/52 ,  A61K36/70 ,  A61K36/708 ,  A61K36/73 ,  A61K36/734 ,  A61K36/76 ,  A61K36/77 ,  A61K36/889 ,  A61K36/90

摘要： The present invention relates to the use of an active substance that promotes the inhibition of AGE formation, for the preparation of a composition for preventing and/or combating the decrease in elastic and plastic properties of tissues, and in particular of the skin, for inhibiting AGE formation, or for preventing and/or combating protein glycation at the cutaneous level. The invention also relates to a method of screening for such active substances.

摘要翻译： 本发明涉及促进AGEs形成抑制活性物质的用途，用于制备组合物以预防和/或防止组织，特别是皮肤的弹性和塑性特性降低以抑制 AGEs的形成，或用于预防和/或防治皮肤中蛋白质的糖基化。 本发明还涉及筛选这种活性物质的方法。