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    THE USE OF GLYCEROL WITH LIMITED FEED OF CARBOHYDRATES FOR FERMENTATION
    1.
    发明公开
    THE USE OF GLYCEROL WITH LIMITED FEED OF CARBOHYDRATES FOR FERMENTATION 审中-公开
    佛罗伦萨VERBENRENZTERZUFÜHRUNGVON KOHLENHYDRATEN ZUR FERMENTIERUNG

    公开(公告)号：EP3119898A1

    公开(公告)日：2017-01-25

    申请号：EP15711141.0

    申请日：2015-03-18

    申请人： BASF SE

    发明人： DANTAS COSTA, Esther ,  ZELDER, Oskar ,  SCHRÖDER, Hartwig ,  HAEFNER, Stefan ,  KRAWCZYK, Joanna Martyna ,  VON ABENDROTH, Gregory ,  RIEDELE, Christian ,  RENZ, Torsten

    IPC分类号： C12P7/46 ,  C12N9/04 ,  C12N9/10 ,  C07K14/285

    CPC分类号： C12N9/0006 ,  C07K14/285 ,  C12N9/1029 ,  C12P7/46 ,  C12Y101/01027 ,  C12Y203/01054

    摘要： The present invention relates to a process for producing an organic acid by fermentation, comprising the process steps: I) cultivating microorganisms in a culture medium to which are fed, as assimilable carbon sources, glycerol and a further carbonaceous compound, to allow the microorganisms to produce the organic acid, thereby obtaining a fermentation broth comprising the organic acid; II) recovering the organic acid or the salt thereof from the fermentation broth obtained in process step I); wherein, at least for a certain period of time in process step I), the consumption rate of the further carbonaceous compound (CRc.c.; in g per liter per hour) is lower than the maximum theoretical consumption rate of the further carbonaceous compound (CRc.c. max; in g per liter per hour).

    摘要翻译： 本发明涉及通过发酵生产有机酸的方法，包括以下工艺步骤：I）在作为可同化碳源进料的培养基中培养微生物甘油和另外的碳质化合物，以使微生物 产生有机酸，从而得到包含有机酸的发酵液; II）从方法步骤I）中获得的发酵液中回收有机酸或其盐; 其中，至少在处理步骤I）中的一段时间内，进一步的碳质化合物（CRc.c;以g / l / h）的消耗速率低于进一步的碳质化合物的最大理论消耗速率 （CRc.c.max;以g每升/小时计）。