公开(公告)号：EP1551324A1

公开(公告)日：2005-07-13

申请号：EP03759483.5

申请日：2003-09-24

申请人： Baxter International Inc. ,  Cerus Corporation

发明人： METZEL, Peyton, S. ,  BISCHOF, Daniel, F. ,  MOORE, Joseph, S. ,  DING, Yuanpang, Samuel ,  HERMAN, Robert, E. ,  MAYAUDON, Veronique ,  SOUDANT, Gregory ,  LECOUR, Daniel,Baxter S.A. ,  BRIERE, Yvon ,  DIMINO, George, D. ,  HEI, Derek, J. ,  LAIRD, James ,  MOHIUDDIN, Mahmood

IPC分类号： A61B19/00 ,  B01D15/00

CPC分类号： A61J1/10 ,  A61L2/0011 ,  A61L2/0082 ,  A61L2/24 ,  A61L2202/22 ,  A61M1/0218 ,  A61M1/0236 ,  A61M1/0277 ,  A61M1/3681 ,  A61M1/3686 ,  B01J20/20 ,  B01J20/26

摘要： Apparatus, systems and methods are disclosed for treating a biological fluid with light. A disposable fluid processing set including integrally connected containers and tubing and a holder or organizer for receiving at least some of the containers and tubing are disclosed.

公开(公告)号：EP1094883A1

公开(公告)日：2001-05-02

申请号：EP99931936.1

申请日：1999-06-25

申请人： BAXTER INTERNATIONAL INC. ,  Cerus Corporation

发明人： BOGGS, Daniel, R. ,  HEI, Derek, J. ,  STERNBERG, Schmuel ,  PAULEY, Robin, G. ,  MCLARTY, Donna, L.

IPC分类号： B01D61/00

CPC分类号： B01D69/148 ,  A61M1/02 ,  A61M1/3686 ,  B01D63/087 ,  B01D63/14 ,  B01D65/022 ,  B01D67/0009 ,  B01D67/0086 ,  B01D69/02 ,  B01D69/10 ,  B01D69/147 ,  B01D71/16 ,  B01D71/30 ,  B01D71/34 ,  B01D71/54 ,  B01D2321/346 ,  B01D2323/42 ,  B01D2325/38

摘要： A membrane (10) and a method for making a membrane (10) are disclosed. The membrane (10) includes a polymeric matrix (16) and a particulate material immobilized within the matrix (16). The membrane (10) may include a support (18) within the core of the mebrane (10) and may further include a skin (19). The membrane (10) may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.

公开(公告)号：EP1191990A1

公开(公告)日：2002-04-03

申请号：EP00939469.3

申请日：2000-05-31

申请人： BAXTER INTERNATIONAL INC. ,  Cerus Corporation

发明人： DE GHELDERE, Serge ,  MOHIUDDIN, Mahmood ,  METZEL, Peyton, S. ,  CIMINO, George, D. ,  HEI, Derek, J. ,  CLARKE, Michael, S.

IPC分类号： B01D15/00

CPC分类号： A61J1/10 ,  A61L2/0023 ,  A61L2/0035 ,  A61L2/0047 ,  A61L2/007 ,  A61L2/0082 ,  A61L2/24 ,  A61L2/26 ,  A61L2202/122 ,  A61L2202/14 ,  A61L2202/22 ,  A61M1/0218 ,  A61M1/0236 ,  A61M1/0277 ,  A61M1/3681 ,  A61M1/3686 ,  B01D15/00

摘要： Apparatus (10), systems and methods are disclosed for treating a biological fluid with light. A container (206) of biological fluid is introduced into a fluid treatment chamber (40) where it is contacted with light provided by one or more light sources (60, 70) in proximity to the fluid treatment chamber (40). A drawer (50) for holding containers of biological fluid introduces the containers (206) into the chamber (40). Containers (206) for holding the biological fluid are marked by the apparatus (10) to indicate the status of the treatment.

公开(公告)号：EP1191990B1

公开(公告)日：2016-03-23

申请号：EP00939469.3

申请日：2000-05-31

申请人： Fenwal, Inc. ,  Cerus Corporation

发明人： DE GHELDERE, Serge ,  MOHIUDDIN, Mahmood ,  METZEL, Peyton, S. ,  CIMINO, George, D. ,  HEI, Derek, J. ,  CLARKE, Michael, S.

IPC分类号： A61J1/10 ,  B01D15/00 ,  A61L2/10 ,  A61M1/02 ,  A61M1/36

CPC分类号： A61J1/10 ,  A61L2/0023 ,  A61L2/0035 ,  A61L2/0047 ,  A61L2/007 ,  A61L2/0082 ,  A61L2/24 ,  A61L2/26 ,  A61L2202/122 ,  A61L2202/14 ,  A61L2202/22 ,  A61M1/0218 ,  A61M1/0236 ,  A61M1/0277 ,  A61M1/3681 ,  A61M1/3686 ,  B01D15/00

公开(公告)号：EP1551324B1

公开(公告)日：2014-12-24

申请号：EP03759483.5

申请日：2003-09-24

申请人： Fenwal, Inc. ,  Cerus Corporation

发明人： METZEL, Peyton, S. ,  BISCHOF, Daniel, F. ,  MOORE, Joseph, S. ,  DING, Yuanpang, Samuel ,  HERMAN, Robert, E. ,  MAYAUDON, Veronique ,  SOUDANT, Gregory ,  LECOUR, Daniel, Baxter S.A. ,  BRIERE, Yvon ,  DIMINO, George, D. ,  HEI, Derek, J. ,  LAIRD, James ,  MOHIUDDIN, Mahmood

IPC分类号： A61B19/00 ,  B01D15/00 ,  A61M1/02 ,  A61M1/36 ,  A61J1/10 ,  A61L2/00 ,  A61L2/24 ,  B01J20/20 ,  B01J20/26

CPC分类号： A61J1/10 ,  A61L2/0011 ,  A61L2/0082 ,  A61L2/24 ,  A61L2202/22 ,  A61M1/0218 ,  A61M1/0236 ,  A61M1/0277 ,  A61M1/3681 ,  A61M1/3686 ,  B01J20/20 ,  B01J20/26

公开(公告)号：EP1181063B8

公开(公告)日：2014-04-02

申请号：EP00937989.2

申请日：2000-05-31

申请人： Fenwal, Inc. ,  Cerus Corporation

发明人： MOHIUDDIN, Mahmood ,  CIMINO, George, D. ,  HEI, Derek, J.

IPC分类号： A61M1/00 ,  B65D81/32

CPC分类号： A61J1/10 ,  A61M1/1694 ,  A61M1/3686

公开(公告)号：EP1181063A1

公开(公告)日：2002-02-27

申请号：EP00937989.2

申请日：2000-05-31

申请人： BAXTER INTERNATIONAL INC. (a Delaware corporation)

发明人： MOHIUDDIN, Mahmood ,  CIMINO, George, D. ,  HEI, Derek, J.

IPC分类号： A61M1/00 ,  B65D81/32

CPC分类号： A61J1/10 ,  A61M1/1694 ,  A61M1/3686

摘要： Containers and methods for making containers are disclosed. The containers (16) include a chamber (36) and a pouch (50) fixed within the chamber (36). During manufacture, the open edges of the pouch (50) are sealed between the walls (24,26) of the container by a seal defining, in part, the peripheral edge of the chamber.

公开(公告)号：EP0840781B1

公开(公告)日：2009-12-09

申请号：EP96921456.8

申请日：1996-06-07

申请人： Cerus Corporation

发明人： HEI, Derek, J.

IPC分类号： C12M1/12 ,  B01D61/00 ,  A61L2/00

CPC分类号： B32B27/12 ,  A61K35/16 ,  A61K35/19 ,  A61K41/0009 ,  A61L2/0035 ,  A61M1/3681 ,  A61M1/3686 ,  B32B5/028 ,  B32B27/36 ,  B32B2367/00 ,  B32B2439/80

摘要： Methods and devices for the removal of psoralens and psoralen photoproducts from blood products are described. The methods include contacting a psoralen- and irradiation-treated blood product with a resin capable of adsorbing psoralens and psoralen photoproducts. The removal process is particularly suitable for use with platelet concentrates and plasma because the process does not have a significant adverse effect on clotting factor function. The methods and devices can be incorporated with apheresis systems and other devices and procedures currently used to process blood products for transfusion.

公开(公告)号：EP1005531A2

公开(公告)日：2000-06-07

申请号：EP98936943.4

申请日：1998-07-21

申请人： Cerus Corporation

发明人： GREENMAN, William, M. ,  GRASS, Joshua, A. ,  TALIB, Sohel ,  STASSINOPOULOS, Adonis ,  HEI, Derek, J. ,  HEARST, John, E.

IPC分类号： C12N5/06 ,  C12N15/01 ,  A61K41/00

CPC分类号： C12N5/0634 ,  A61K35/15 ,  A61K35/17 ,  A61K35/28 ,  C12N2501/06

摘要： The invention provides methods and compositions for treating leukocytes to arrest proliferation of the leukocytes and render them ineffective in eliciting graft-versus-host disease (GVHD), but effective to enhance engraftment of allongeneic donor cells and promote destruction of diseased cells or pathogens. Leukocyte compositions and methods of use of these compositions in alleviating disease, facilitating various types of immune reconstitution and immunotherapy, and enhancing engraftment of allogeneic donor cells, are also provided.

公开(公告)号：EP0840781A1

公开(公告)日：1998-05-13

申请号：EP96921456.0

申请日：1996-06-07

申请人： Cerus Corporation

发明人： HEI, Derek, J.

IPC分类号： A01N1 ,  A61B19 ,  A61K35 ,  A61L2 ,  A61M1 ,  A61M37

CPC分类号： B32B27/12 ,  A61K35/16 ,  A61K35/19 ,  A61K41/0009 ,  A61L2/0035 ,  A61M1/3681 ,  A61M1/3686 ,  B32B5/028 ,  B32B27/36 ,  B32B2367/00 ,  B32B2439/80

摘要： Methods and devices for the removal of psoralens and psoralen photoproducts from blood products are described. The methods include contacting a psoralen- and irradiation-treated blood product with a resin capable of adsorbing psoralens and psoralen photoproducts. The removal process is particularly suitable for use with platelet concentrates and plasma because the process does not have a significant adverse effect on clotting factor function. The methods and devices can be incorporated with apheresis systems and other devices and procedures currently used to process blood products for transfusion.