公开(公告)号：EP0812363A1

公开(公告)日：1997-12-17

申请号：EP96904087.0

申请日：1996-03-01

申请人： BAYER AG

发明人： SMIDT, Hauke ,  FISCHER, Andreas ,  FISCHER, Peter ,  SCHMID, Rolf, D. ,  STELZER, Uwe

IPC分类号： C07C209 ,  C12P13 ,  C12P41

CPC分类号： C12P13/001 ,  C07C209/88 ,  C12P41/007

摘要： A new process is disclosed for preparing (R)-amines having the formula (I), in which R1, R2 and n have the meanings given in the description. For that purpose, racemic N-acyl-amines having the formula (II), in which R?1, R2, R3¿ and n have the meanings given in the description, are reacted with lipases capable of splitting the (R)-enantiomers of N-acyl-amines having the formula (II), in the presence of water and optionally in the presence of an organic diluting agent at a pH value from 3,0 to 10,0 and at temperatures from 0 °C to 80 °C.

公开(公告)号：EP0812363B1

公开(公告)日：2001-01-24

申请号：EP96904087.2

申请日：1996-03-01

申请人： BAYER AG

发明人： SMIDT, Hauke ,  FISCHER, Andreas ,  FISCHER, Peter ,  SCHMID, Rolf, D. ,  STELZER, Uwe

IPC分类号： C12P41/00 ,  C12P13/00

CPC分类号： C12P13/001 ,  C07C209/88 ,  C12P41/007