公开(公告)号：EP1629104A4

公开(公告)日：2006-11-02

申请号：EP04736153

申请日：2004-06-04

申请人： BIOLEADERS CORP ,  M D LAB ,  BIOLEADERS JAPAN CORP ,  KOREA RES INST OF BIOSCIENCE

发明人： SUNG MOON HEE ,  KIM CHUL JOONG ,  JUNG CHANG MIN ,  HONG SEUNG PYO ,  LEE JONG SU ,  CHOI JAE CHUL ,  KIM KWANG ,  SHUNICHI KURODA ,  POO HA RYOUNG

IPC分类号： C12N15/86 ,  A61K39/00 ,  C07K14/025 ,  C07K14/165 ,  C12N9/00 ,  C12N15/74

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K2039/523 ,  C07K2319/00 ,  C12N9/93 ,  C12N15/74 ,  C12N2710/20022 ,  C12N2770/20022

摘要： The present invention relates to a surface expression vector of SARS coronavirus antigen containing a gene encoding an antigen of SARS inducing coronavirus and any one or two or more of genes pgsB, pgsC and pgsA encoding poly-gamma-glutamic acid synthase complex, a microorganism transformed by the surface expression vector, and a SARS vaccine comprising the microorganism. According to the present invention, it is possible to economically produce a vaccine for prevention and treatment of SARS using a recombinant strain expressing an SARS coronavirus antigen on their surface.

公开(公告)号：EP1850870A4

公开(公告)日：2009-01-28

申请号：EP05819088

申请日：2005-12-06

申请人： BIOLEADERS CORP ,  M D LAB CO LTD ,  KOREA RES INST OF BIOSCIENCE

发明人： SUNG MOON HEE ,  KIM CHUL JOONG ,  POO HA RYOUNG ,  HONG SEUNG PYO ,  LEE JONG SOO ,  KIM JI YOUN

IPC分类号： A61K39/39 ,  A61K47/30

CPC分类号： A61K39/39 ,  A61K2039/55516