PROCEDE ET KIT POUR ETABLIR IN VITRO UN PRONOSTIC DE SEVERITE CHEZ UN PATIENT EN CHOC SEPTIQUE
    9.
    发明公开
    PROCEDE ET KIT POUR ETABLIR IN VITRO UN PRONOSTIC DE SEVERITE CHEZ UN PATIENT EN CHOC SEPTIQUE 有权
    方法和试剂盒的体外CREATING严重感染性休克预测在一个单一的患者

    公开(公告)号:EP2943588A1

    公开(公告)日:2015-11-18

    申请号:EP14703127.2

    申请日:2014-01-10

    IPC分类号: C12Q1/68

    摘要: The invention concerns a method for establishing,
    in vitro , a prognosis of severity in a septic shock patient, comprising the following steps: (i) using a biological sample taken from said patient, measuring,
    in vitro , the level of expression of the expression product of at least one gene chosen from the
    lilrb2 and
    lilrb1 genes, (ii) comparing the level of expression of the expression product of said at least one gene with a control level of expression of the expression product of the same gene indicating a good prognosis of severity, in which a level of expression of the expression product of said at least one gene that is lower than said control level of expression indicates a poor prognosis of severity for the patient, and a kit for implementing the method.

    摘要翻译: 本发明的主题是一种用于制造严重性的体外预后的用于在感染性休克的患者,其中包括以下步骤的方法:(i)从所述LILRB2和lilrb1选择的至少一种基因的表达产物的表达水平 基因在体外测量来自患者的生物样品的基础上,(ii)所述至少一种基因的表达产物的表达水平与对照表达水平相比相同的表达产物的, 基因,与严重程度的良好的预后,其中下面表达的对照水平的至少一种基因的表达产物的表达水平指示患者严重程度的预后不良,因此用于实现该方法的试剂盒。