摘要:
The invention concerns a method for establishing, in vitro , a prognosis of severity in a septic shock patient, comprising the following steps: (i) using a biological sample taken from said patient, measuring, in vitro , the level of expression of the expression product of at least one gene chosen from the lilrb2 and lilrb1 genes, (ii) comparing the level of expression of the expression product of said at least one gene with a control level of expression of the expression product of the same gene indicating a good prognosis of severity, in which a level of expression of the expression product of said at least one gene that is lower than said control level of expression indicates a poor prognosis of severity for the patient, and a kit for implementing the method.
摘要:
The present invention relates to a method for determining the likelihood of a patient contracting a nosocomial infection and to a method for determining the prognosis of the course of a septic syndrome in a patient, according to which: a. a biological sample is obtained from the patient and biological material is extracted from the biological sample; b. at least one specific reagent is obtained from an expression construct of at least one target gene selected from target genes S100A9 and S100A8; c. the expression of at least one of the target genes S100A9 and S100A8 is determined, an overexpression relative to a predetermined threshold value indicating the likelihood of contracting a nosocomial infection as well as indicating a poor prognosis of the course of a septic syndrome.