公开(公告)号：EP2934572A4

公开(公告)日：2016-11-23

申请号：EP13865767

申请日：2013-12-20

申请人： BIOMATRICA INC

发明人： WHITNEY SCOTT E ,  DE LOS RIOS STEPHANIE ,  GHIRMAI SENAIT ,  MULLER ROLF ,  LIBERAL VASCO ,  WILKINSON STEVEN P

IPC分类号： C12Q1/68 ,  C12N9/12 ,  C12N9/96

CPC分类号： C12N9/1252 ,  C12N9/1247 ,  C12N9/96 ,  C12Q1/686 ,  C12Y207/07006 ,  C12Y207/07007 ,  C12Q2521/101 ,  C12Q2527/125 ,  C12Q2563/137

摘要： Described herein are stabilized polymerase compositions comprising a polymerase and an polymerase stabilizing agent, such as a non-detergent zwitterionic stabilizer or a cationic ester disclosed, for use in nucleic acid amplification or nucleic acid sequencing. Compositions are provided for the stabilization of one or more polymerases in a single stabilized liquid formulation. Also disclosed are methods for making and using stabilized polymerase compositions and kits for nucleic acid amplification and sequencing comprising the stabilized polymerase compositions provided.

摘要翻译： 本文描述了稳定的聚合酶组合物，其包含用于核酸扩增或核酸测序的聚合酶和聚合酶稳定剂，例如所公开的非洗涤剂两性离子稳定剂或阳离子酯。 提供组合物用于在单一稳定的液体制剂中稳定一种或多种聚合酶。 还公开了制备和使用稳定的聚合酶组合物和用于核酸扩增和测序的试剂盒的方法，其包含提供的稳定的聚合酶组合物。

公开(公告)号：EP3154338A4

公开(公告)日：2017-11-15

申请号：EP15805897

申请日：2015-06-09

申请人： BIOMATRICA INC

发明人： MULLER ROLF ,  DESHARNAIS JOEL ,  WILKINSON STEVEN P ,  ARENDT VICTORIA ,  DIAZ PAUL

IPC分类号： A01N1/02 ,  A61K35/19

CPC分类号： A01N1/0226 ,  A01N1/021 ,  A61K35/19

摘要： Provided herein are formulations and methods for the stabilization of one or more thrombocytes at ambient temperatures. Also provided are formulations and methods for the stabilization of one or more thrombocytes in an inactivated state in a blood sample at ambient temperatures. Further provided are articles of manufacture and kits and methods for substantially stable storage of one or more thrombocyte at ambient temperatures.