利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

11 条记录 (耗时 0.014 秒)

    GENE SEQUENCING STRUCTURE, CHIP, SYSTEM AND GENE SEQUENCING METHOD
    2.
    发明公开
    GENE SEQUENCING STRUCTURE, CHIP, SYSTEM AND GENE SEQUENCING METHOD 审中-公开

    公开(公告)号：EP3656843A1

    公开(公告)日：2020-05-27

    申请号：EP18765347.2

    申请日：2018-02-11

    申请人： BOE Technology Group Co., Ltd. ,  Beijing BOE Optoelectronics Technology Co., Ltd.

    发明人： CAI, Peizhi ,  PANG, Fengchun ,  LIU, Huazhe

    IPC分类号： C12M1/34 ,  C12Q1/68

    摘要： The present disclosure relates to a gene sequencing structure, chip, system, and method. The gene sequencing structure comprises: a first electrode and a second electrode spaced apart from each other, a semiconductor layer, a sensing electrode, an insulating layer, and a sensitive film layer. The first electrode is connected to the second electrode via the semiconductor layer, the sensing electrode is in contact with the sensitive film layer, and the insulating layer isolates each of the sensitive film layer and the sensing electrode from each of the first electrode, the second electrode, and the semiconductor layer, wherein the sensitive film layer generates charges in response to receiving ions generated by base pairing during gene sequencing.

    GENE SEQUENCING CHIP AND GENE SEQUENCING METHOD
    3.
    发明公开
    GENE SEQUENCING CHIP AND GENE SEQUENCING METHOD 审中-公开

    公开(公告)号：EP3623462A1

    公开(公告)日：2020-03-18

    申请号：EP18739446.5

    申请日：2018-01-02

    申请人： BOE Technology Group Co., Ltd. ,  Beijing BOE Optoelectronics Technology Co., Ltd.

    发明人： GENG, Yue ,  PANG, Fengchun ,  CAI, Peizhi ,  GU, Le

    IPC分类号： C12M1/34 ,  C12Q1/68

    摘要： Embodiments of the disclosure provide a gene sequencing chip, including: an upper substrate including a plurality of liquid inlets for inletting liquid drops; a lower substrate opposite to the upper substrate and spaced therefrom by a gap, the gap being provided for allowing the liquid drops to move therein, the lower substrate including a liquid drop operation region, the liquid drop operation region including a manipulation electrode array. The manipulation electrode array includes multiple first sub-arrays for preparing a gene library, multiple second sub-arrays for sequencing the prepared gene library, each first sub-array being adjacent to one of the second sub-arrays. Based on the gene sequencing chip provided in this disclosure, operations to tiny liquid drops such as movement, fusion and splitting can be accurately manipulated by using digital microfluidic techniques, and all steps of the gene sequencing from library preparation to gene sequencing can be completed in a programmatic manner on one chip. The chip has a high degree of integration, the liquid drops can be manipulated accurately, the consumption of the reagents can be reduced, and the preparation process is simple and mature.

    DETECTION SUBSTRATE AND MANUFACTURING METHOD THEREFOR, AND METHOD FOR DETECTING NUCLEIC ACIDS
    4.
    发明公开
    DETECTION SUBSTRATE AND MANUFACTURING METHOD THEREFOR, AND METHOD FOR DETECTING NUCLEIC ACIDS 审中-公开

    公开(公告)号：EP3561510A1

    公开(公告)日：2019-10-30

    申请号：EP17835577.2

    申请日：2017-07-12

    申请人： BOE Technology Group Co., Ltd. ,  Beijing BOE Optoelectronics Technology Co., Ltd.

    发明人： PANG, Fengchun ,  CAI, Peizhi ,  GENG, Yue

    IPC分类号： G01N33/53 ,  C12Q1/68 ,  C12M1/40

    摘要： A detection substrate and a manufacturing method thereof, and a nucleic acid detecting method are provided. The detection substrate includes at least one detection unit (100) disposed on a base substrate (10), the detection unit (100) including a first electrode (11), a second electrode (13) and a colloid layer (17), the second electrode (13) disposed on a side of the first electrode (11) away from the base substrate (10), the second electrode (13) including at least one hollowed structure (1300), the second electrode (13) and the first electrode (11) being insulated from each other, and the first electrode (11) and the second electrode (13) being configured to be applied with voltages respectively; the colloid layer (17) at least disposed on the at least one hollowed structure (1300) of the second electrode (13), the colloid layer (17) including a linker (170) configured to be paired with a target nucleic acid (18). The detection substrate performs the amplification and detection of the nucleic acid by applying voltages to the first electrode (11) and the second electrode (13) of the detection unit (100) respectively. A requirement on the structure and appearance of the first electrode (11) and the second electrode (13) are simple, which simplifies the process difficulty.

    CHIP, DETECTION SYSTEM, AND GENE SEQUENCING METHOD
    6.
    发明公开
    CHIP, DETECTION SYSTEM, AND GENE SEQUENCING METHOD 审中-公开

    公开(公告)号：EP3626811A1

    公开(公告)日：2020-03-25

    申请号：EP17892073.2

    申请日：2017-12-15

    申请人： BOE Technology Group Co., Ltd. ,  Beijing BOE Optoelectronics Technology Co., Ltd.

    发明人： PANG, Fengchun ,  CAI, Peizhi ,  GENG, Yue

    IPC分类号： C12M1/38 ,  C12M1/00

    摘要： A chip, a detection system and a gene sequencing method are provided. When the chip is used for gene sequencing, sample genes and reversible terminating nucleotides are added into micropores and matched therein to release hydrogen ions such that a Nernst potential is induced on an ion-sensitive film surface, and a voltage is applied to the transparent electrode layer to generate an electric field, thereby controlling the switching layer to change its state, and then a base type of the genes is determined based on a type of reversible terminating nucleotide corresponding to information of light emitted from the switching layer upon changes in the state of the switching layer, thereby gene sequencing is achieved. The chip has a simple structure and low fabrication cost, and the reversible terminating nucleotides for matching sequencing require no fluorescent labeling, and optical systems such as a backlight source and a laser light source are unnecessary, which greatly reduces the cost and time for gene sequencing.

    ANTENNA STRUCTURE AND MODULATION METHOD THEREFOR
    7.
    发明公开
    ANTENNA STRUCTURE AND MODULATION METHOD THEREFOR 审中-公开

    公开(公告)号：EP3780271A1

    公开(公告)日：2021-02-17

    申请号：EP19784231.3

    申请日：2019-04-03

    申请人： BOE TECHNOLOGY GROUP CO., LTD. ,  Beijing BOE Optoelectronics Technology Co., Ltd.

    发明人： WU, Jie ,  TING, Tien Lun ,  KONG, Xiangzhong ,  CAO, Xue ,  WANG, Ying ,  LI, Liang ,  CAI, Peizhi ,  CHE, Chuncheng

    IPC分类号： H01Q1/38 ,  H01Q9/06

    摘要： An antenna structure and a modulation method therefor. The antenna structure comprises a radiation patch (120), a radio-frequency port (130), a first signal line (140), a second signal line (150), a power splitter (160), and a first phase modulator (170). The radiation patch (120) comprises a first feeding point (121) and a second feeding point (122). One end of the first signal line (140) is connected to the first feeding point (121). One end of the second signal line (150) is connected to the second feeding point (122). The power splitter (160) is separately connected to the radio-frequency port (130), the other end of the first signal line (140), and the other end of the second signal line (150), and is configured to allocate electromagnetic waves of the radio-frequency port to the first signal line (140) and the second signal line (150); and the first phase modulator (170) is configured to modulate the phase of the electromagnetic waves of the first signal line (140). Accordingly, the antenna structure can receive and transmit left-handed circular polarized wave, right-handed circular polarized wave, and linear polarized wave by using the single radio-frequency port.