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公开(公告)号：EP1019040A1
公开(公告)日：2000-07-19
申请号：EP98923600.5
申请日：1998-05-21
申请人： Bayer Corporation
发明人： RANGES, Gerald , SCOTT, William , BOMBARA, Michael , RAUNER, Deborah , REDMAN, Aniko , SMITH, Roger , PAULSEN, Holger , CHEN, Jinshan , GUNN, David , RENICK, Joel
CPC分类号： A61K31/433 , A61K31/341 , A61K31/381 , A61K31/40 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/473
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.
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2.发明公开INHIBITION OF RAF KINASE USING SYMMETRICAL AND UNSYMMETRICAL SUBSTITUTED DIPHENYL UREAS 有权RAF激酶的抑制使用平衡和不平衡取代脲
公开(公告)号：EP1049664A1
公开(公告)日：2000-11-08
申请号：EP98963809.3
申请日：1998-12-22
申请人： Bayer Corporation
发明人： MILLER, Scott , OSTERHOUT, Martin , DUMAS, Jacques , KHIRE, Uday , LOWINGER, Timothy, Bruno , RIEDL, Bernd , SCOTT, William, J. , SMITH, Roger, A. , WOOD, Jill, E. , GUNN, David , RODRIGUEZ, Mareli , WANG, Ming
IPC分类号： C07C275/24 , C07D213/02 , C07D333/02 , A61K31/17 , A61K31/38 , A61K31/44
CPC分类号： C07D213/40 , C07C275/36 , C07D213/32 , C07D213/50 , C07D213/65 , C07D213/68 , C07D213/69 , C07D213/70 , C07D213/75 , C07D213/81 , C07D213/89 , C07D215/20 , C07D239/38 , C07D277/68 , C07D317/64 , C07D401/04 , C07D401/12 , C07D409/12
摘要： This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
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3.发明授权
公开(公告)号：EP1019040B1
公开(公告)日：2004-09-29
申请号：EP98923600.5
申请日：1998-05-21
申请人： Bayer Corporation
发明人： RANGES, Gerald , SCOTT, William , BOMBARA, Michael , RAUNER, Deborah , REDMAN, Aniko , SMITH, Roger , PAULSEN, Holger , CHEN, Jinshan , GUNN, David , RENICK, Joel
CPC分类号： A61K31/433 , A61K31/341 , A61K31/381 , A61K31/40 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/473
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.
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4.发明公开
公开(公告)号：EP1042305A1
公开(公告)日：2000-10-11
申请号：EP98964221.0
申请日：1998-12-22
申请人： Bayer Corporation
发明人： MILLER, Scott , OSTERHOUT, Martin , DUMAS, Jacques , KHIRE, Uday , LOWINGER, Timothy, Bruno , RIEDL, Bernd , SCOTT, William, J. , SMITH, Roger, A. , WOOD, Jill, E. , GUNN, David , HATOUM-MOKDAD, Holia , RODRIGUEZ, Mareli , SIBLEY, Robert , WANG, Ming , TURNER, Tiffany , BRENNAN, Catherine
IPC分类号： C07D273/00 , C07D275/00 , A61K31/17
CPC分类号： C07D207/27 , A61K31/17 , A61K31/40 , A61K31/403 , A61K31/4035 , A61K31/425 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4436 , A61K31/4439 , A61K31/535 , A61K31/5375 , C07C205/11 , C07C205/22 , C07C205/37 , C07C205/38 , C07C205/57 , C07C205/58 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07C275/42 , C07C309/88 , C07C311/48 , C07C317/42 , C07D207/26 , C07D207/404 , C07D209/76 , C07D209/86 , C07D209/88 , C07D213/40 , C07D213/53 , C07D213/68 , C07D213/70 , C07D231/08 , C07D233/22 , C07D233/70 , C07D263/58 , C07D277/68 , C07D295/185 , C07D307/20 , C07D333/20 , C07D409/12 , Y02A50/411
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
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