专利检索 ap:("Bayer Intellectual Property GmbH") AND inv:"VON DEGENFELD, Georges" 第 1 页

1.

发明授权
SUBSTITUIERTE PIPERIDINE ALS PAR-1 ANTAGONISTEN 有权
标题翻译：取代的哌啶ALS PAR-1拮抗剂

公开(公告)号：EP2411363B1

公开(公告)日：2015-10-07

申请号：EP10708146.5

申请日：2010-03-12

申请人： Bayer Intellectual Property GmbH

发明人： JESKE, Mario , HEIMBACH, Dirk , RÖHRIG, Susanne , CANCHO GRANDE, Yolanda , SCHNEIDER, Dirk , RESTER, Ulrich , BENDER, Eckhard , MEININGHAUS, Mark , ZIMMERMANN, Katja , ZUBOV, Dmitry , BUCHMÜLLER, Anja , VON DEGENFELD, Georges , GERDES, Christoph , GERISCH, Michael , GNOTH, Mark, Jean , GERICKE, Kersten, Matthias

IPC分类号： C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/06 , A61K31/451 , A61K31/4525 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K9/20 , A61K9/08 , A61K9/10

CPC分类号： C07D417/06 , A61K9/0019 , A61K9/10 , A61K9/2018 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K47/10 , A61K47/36 , C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12

2.

发明公开
ADENOSINE A1 AGONISTS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION 有权
标题翻译：腺苷A1治疗青光眼和眼高压

公开(公告)号：EP2611415A1

公开(公告)日：2013-07-10

申请号：EP11752517.0

申请日：2011-08-29

申请人： Bayer Intellectual Property GmbH

发明人： KLAR, Jürgen , VON DEGENFELD, Georges , LERCHEN, Hans-Georg , ALBRECHT-KÜPPER, Barbara , KNORR, Andreas , SANDNER, Peter , MEIBOM, Daniel

IPC分类号： A61K9/00 , A61K31/4427 , A61K31/4439 , A61P27/06

CPC分类号： A61K31/4439 , A61K9/0048 , A61K9/08 , A61K38/05 , A61K45/06 , C07D413/12 , C07D417/12 , C07D417/14

摘要： The present invention relates to the use of selective adenosine A1 agonists, in particular the dicyanopyridines of formula (I), for the treatment and/or prophylaxis of glaucoma and ocular hypertension as well as the their use for the production of a medicament for the treatment and/or prophylaxis of glaucoma and ocular hypertension.

3.

发明授权
ADENOSINE A1 AGONISTS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION 有权
标题翻译：腺苷A1治疗青光眼和眼高压

公开(公告)号：EP2611415B1

公开(公告)日：2016-02-24

申请号：EP11752517.0

申请日：2011-08-29

申请人： Bayer Intellectual Property GmbH

发明人： KLAR, Jürgen , VON DEGENFELD, Georges , LERCHEN, Hans-Georg , ALBRECHT-KÜPPER, Barbara , KNORR, Andreas , SANDNER, Peter , MEIBOM, Daniel

IPC分类号： A61K9/00 , A61K31/4427 , A61K31/4439 , A61P27/06 , A61K45/06 , A61K9/08 , C07D413/12 , C07D417/12 , C07D417/14

CPC分类号： A61K31/4439 , A61K9/0048 , A61K9/08 , A61K38/05 , A61K45/06 , C07D413/12 , C07D417/12 , C07D417/14

4.

发明公开
THE USE OF sGC STIMULATORS, sGC ACTIVATORS, ALONE AND COMBINATIONS WITH PDE5 INHIBITORS FOR THE TREATMENT OF SYSTEMIC SCLEROSIS (SSc). 有权
标题翻译：兴奋剂的sGC，sGC活化剂，单独或与PDE5抑制剂用于全身硬化症治疗的组合（SSC）的使用

公开(公告)号：EP2576548A1

公开(公告)日：2013-04-10

申请号：EP11722786.8

申请日：2011-05-24

申请人： Bayer Intellectual Property GmbH

发明人： HIRTH-DIETRICH, Claudia , SANDNER, Peter , STASCH, Johannes-Peter , KNORR, Andreas , VON DEGENFELD, Georges , HAHN, Michael , FOLLMANN, Markus

IPC分类号： C07D471/04 , A61K31/437 , A61P9/00 , A61P15/00

CPC分类号： C07D495/04 , A61K31/197 , A61K31/426 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K45/06 , C07C229/38 , C07D261/10 , C07D277/30 , C07D333/34 , C07D401/04 , C07D417/06 , C07D471/04 , C07D487/04 , A61K2300/00

摘要： The use of sGC stimulators, sGC activators alone, or in combination with PDE5 inhibitors for the prevention and treatment of fibrotic diseases, such as systemic sclerosis, scleroderma, and the concomitant fibrosis of internal organs.

摘要翻译： 使用sGC刺激剂，sGC的活化剂单独或与PDE5抑制剂对纤维化疾病，：如全身性硬化症，硬皮病，及内脏的伴随纤维化的预防和治疗组合。

5.

发明授权
SUBSTITUIERTE (OXAZOLIDINON-5-YL-METHYL) -2-THIOPHEN-CARBOXAMIDE UND IHRE VERWENDUNG IM GEBIET DER BLUTGERINNUNG 有权
标题翻译：取代的（恶唑烷酮-5-基 - 甲基）-2-噻吩甲酰胺和它们在血液凝固领域

公开(公告)号：EP2170877B1

公开(公告)日：2012-11-21

申请号：EP08773372.1

申请日：2008-06-07

申请人： Bayer Intellectual Property GmbH

发明人： ALLERHEILIGEN, Swen , BAUSER, Marcus , HEIMBACH, Dirk , HEITMEIER, Stefan , GNOTH, Mark, Jean , GERDES, Christoph , VON DEGENFELD, Georges , RÖHRIG, Susanne , RESTER, Ulrich , DITTRICH-WENGENROTH, Elke , SAATMANN, Uwe , TERSTEEGEN, Adrian , KRÜGER, Joachim , PAULSEN, Holger

IPC分类号： C07D413/14 , A61K31/4439 , A61P7/00

CPC分类号： C07D413/14

6.

发明授权
SUBSTITUIERTE PIPERIDINE 有权
标题翻译：取代的哌啶

公开(公告)号：EP2435428B1

公开(公告)日：2013-07-31

申请号：EP10721991.7

申请日：2010-05-14

申请人： Bayer Intellectual Property GmbH

发明人： HEIMBACH, Dirk , RÖHRIG, Susanne , CANCHO GRANDE, Yolanda , RESTER, Ulrich , BENDER, Eckhard , ZIMMERMANN, Katja , ZUBOV, Dmitry , BUCHMÜLLER, Anja , VON DEGENFELD, Georges , GERDES, Christoph , GNOTH, Mark, Jean , GERICKE, Kersten, Matthias , JESKE, Mario

IPC分类号： C07D413/06 , C07D417/06 , C07D211/20 , C07D211/22 , C07D211/24 , C07D211/26 , C07D211/34 , C07D401/06

CPC分类号： C07D211/34 , C07D211/20 , C07D211/22 , C07D211/24 , C07D211/26 , C07D401/06 , C07D417/06

7.

发明公开
sGC STIMULATORS OR sGC ACTIVATORS ALONE AND IN COMBINATION WITH PDE5 INHBITORS FOR THE TREATMENT OF CYSTIC FIBROSIS 有权
标题翻译： SGC SGC刺激剂或活化剂单独或与PDE5抑制剂囊性纤维化的治疗组合

公开(公告)号：EP2531187A1

公开(公告)日：2012-12-12

申请号：EP11701683.2

申请日：2011-02-03

申请人： Bayer Intellectual Property GmbH

发明人： SANDNER, Peter , VON DEGENFELD, Georges , STASCH, Johannes-Peter

IPC分类号： A61K31/18 , A61K31/194 , A61K31/427 , A61K31/4418 , A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K31/53 , A61K45/06 , A61P11/00

CPC分类号： A61K45/06 , A61K31/18 , A61K31/194 , A61K31/427 , A61K31/4418 , A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K31/53 , A61K2300/00

摘要： The present invention relates to soluble guanylate cyclase (sGC) and to phosphodiesterases (PDEs) and the pharmacology of sGC stimulators, sGC activators and PDE inhibitors. More particularly, the invention relates to the use of sGC stimulators and sGC activators in combination with PDE5 inhibitors for preparation of medicaments for the treatment of Cystic Fibrosis (CF).