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公开(公告)号：EP3700913A1
公开(公告)日：2020-09-02
申请号：EP18785394.0
申请日：2018-10-17
发明人： COLLIN-KROEPELIN, Marie-Pierre , KOLKHOF, Peter , NEUBAUER, Thomas , FUERSTNER, Chantal , POOK, Elisabeth , WITTWER, Matthias, Beat , SCHMECK, Carsten , WASNAIRE, Pierre , SCHIRMER, Heiko , CERNECKA, Hana , DROEBNER, Karoline , TINEL, Hanna , BUCHMUELLER, Anja , MONDRITZKI, Thomas , KRETSCHMER, Axel , LUSTIG, Klemens , FRICKE, Robert , LEVILAIN, Guillaume , KRENZ, Ursula , WITOWSKI, Norbert
IPC分类号： C07F9/09 , A61P9/00 , C07D401/14
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公开(公告)号：EP3700900A1
公开(公告)日：2020-09-02
申请号：EP18785401.3
申请日：2018-10-17
发明人： COLLIN-KRÖPELIN, Marie-Pierre , KOLKHOF, Peter , NEUBAUER, Thomas , FÜRSTNER, Chantal , POOK, Elisabeth , WITTWER, Matthias, Beat , LUSTIG, Klemens , TINEL, Hanna , LINDNER, Niels , SCHIRMER, Heiko
IPC分类号： C07D401/14 , A61K31/4196 , A61P9/00 , A61P13/00
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公开(公告)号：EP3487856A1
公开(公告)日：2019-05-29
申请号：EP17742202.9
申请日：2017-07-10
发明人： DELBECK, Martina , HAHN, Michael , MÜLLER, Thomas , LUSTIG, Klemens , ANLAHR, Johanna , ALBUS, Udo , GEHRING, Doris , ROSENSTEIN, Björn , COLLINS, Karl , LINDNER, Niels , NICOLAI, Janine , BECK-BROICHSITTER, Moritz
IPC分类号： C07D471/08 , C07D498/08 , A61K31/439 , A61K31/5386 , A61P25/00
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4.发明公开
公开(公告)号：EP3638676A1
公开(公告)日：2020-04-22
申请号：EP18733193.9
申请日：2018-06-07
发明人： DELBECK, Martina , HAHN, Michael , MÜLLER, Thomas , LUSTIG, Klemens , ANLAHR, Johanna , COLLINS, Karl , NICOLAI, Janine , BECK-BROICHSITTER, Moritz , ALBUS, Udo , GEHRING, Doris , ROSENSTEIN, Björn , DANG, Hongkai , DUAN, Dehe , YANG, Jianfei , CHEN, Denghui
IPC分类号： C07D471/18 , C07D487/04 , C07D487/18 , C07D498/18 , A61P11/00 , A61K31/551 , A61K31/5386
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公开(公告)号：EP3515919A1
公开(公告)日：2019-07-31
申请号：EP17765199.9
申请日：2017-09-18
发明人： HÄRTER, Michael , KOSEMUND, Dirk , CANCHO GRANDE, Yolanda , DELBECK, Martina , KALTHOF, Bernd , LUSTIG, Klemens , SÜSSMEIER, Frank
IPC分类号： C07D495/04 , A61K31/519 , A61P11/06 , A61P11/08 , A61P35/00 , A61P9/00
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公开(公告)号：EP3455224A1
公开(公告)日：2019-03-20
申请号：EP17723053.9
申请日：2017-05-08
发明人： BIBER, Nicole , BROCKSCHNIEDER, Damian , GERICKE, Kersten Matthias , KÖLLING, Florian , LUSTIG, Klemens , MEDING, Jörg , MEIER, Heinrich , NEUBAUER, Thomas , SCHÄFER, Martina , TIMMERMANN, Andreas , ZUBOV, Dmitry , TERJUNG, Carsten , LINDNER, Niels , BADOCK, Volker , MOOSMAYER, Dieter , MIYATAKE ONDOZABAL, Hideki , MOORE, Stephen , SCHULZ, Alexander
IPC分类号： C07D471/04 , C07D519/00 , A61K31/437 , A61K31/444 , A61K31/4375 , A61K31/4709 , A61K31/506 , A61K31/497 , A61P11/00 , A61P9/10 , A61K45/06
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公开(公告)号：EP3452468A1
公开(公告)日：2019-03-13
申请号：EP17720501.0
申请日：2017-05-02
发明人： COLLIN-KRÖPELIN, Marie-Pierre , KOLKHOF, Peter , NEUBAUER, Thomas , FÜRSTNER, Chantal , POOK, Elisabeth , WITTWER, Matthias, Beat , LUSTIG, Klemens , BUCHMÜLLER, Anja , TINEL, Hanna , DRÖBNER, Karoline , MONDRITZKI, Thomas , SCHIRMER, Heiko , SCHMECK, Carsten , WASNAIRE, Pierre , CERMECKA, Hana , KRETSCHMER, Axel
IPC分类号： C07D403/06 , C07D403/14 , A61K31/4196 , A61P9/00 , A61P13/00
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公开(公告)号：EP3386993A1
公开(公告)日：2018-10-17
申请号：EP16805135.7
申请日：2016-12-02
发明人： DELBECK, Martina , HAHN, Michael , MÜLLER, Thomas , MEIER, Heinrich , LUSTIG, Klemens , MOSIG, Johanna , TOSCHI, Luisella , ALBUS, Udo , GEHRING, Doris , ROSENSTEIN, Björn
IPC分类号： C07D519/00 , A61K31/437 , A61P11/00
CPC分类号： C07D519/00
摘要： The invention relates to novel (2-phenylimidazo[1,2-a]pyridin-3-yl)methyl-substituted perhydropyrrolo[3,4-c]pyrrole derivatives, to methods for producing same, to the use thereof alone or in combination for the treatment and/or prevention of diseases, and to the use thereof for producing drugs for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of breathing disorders including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring.
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公开(公告)号：EP3055313B1
公开(公告)日：2017-11-22
申请号：EP14777656.1
申请日：2014-10-02
发明人： HÄRTER, Michael , DELBECK, Martina , KALTHOF, Bernd , LUSTIG, Klemens , LINDNER, Niels , KAST, Raimund , WASNAIRE, Pierre , SÜSSMEIER, Frank
IPC分类号： C07D495/04 , A61K31/519 , A61P11/08
CPC分类号： C07D495/04 , A61K31/519 , A61K45/06 , C07D519/00
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10.发明公开
公开(公告)号：EP3215498A1
公开(公告)日：2017-09-13
申请号：EP15788389.3
申请日：2015-10-30
发明人： SCHMECK, Carsten , GERISCH, Michael , GRIEBENOW, Nils , KOLKHOF, Peter , KÖLLING, Florian , ENGELEN, Anna , KRETSCHMER, Axel , LANG, Dieter , LUSTIG, Klemens , MONDRITZKI, Thomas , POOK, Elisabeth , BECK, Hartmut , SÜSSMEIER, Frank , VOLLMER, Sonja , WASNAIRE, Pierre
IPC分类号： C07D403/06 , A61K31/4196 , A61P9/00 , A61P13/00
CPC分类号： C07D249/12 , A61K31/4196 , A61K45/06 , C07D403/06
摘要： The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
摘要翻译： 本发明涉及新的5-（羟基烷基）-1-苯基-1,2,4-三唑衍生物，涉及这些化合物的制备方法，涉及含有这些化合物的药物组合物，以及涉及这些化合物或组合物 用于治疗和/或预防疾病，特别是用于治疗和/或预防心血管和肾疾病。
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