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公开(公告)号：EP2817405A1
公开(公告)日：2014-12-31
申请号：EP13706481.2
申请日：2013-02-20
发明人： PASTOR, Andre , SELETZKY, Juri , BROD, Helmut , KAULING, Joerg , COMMER, Peter
CPC分类号： C12M33/22 , C12M23/06 , C12M23/14 , C12M23/26 , C12M23/28 , C12M27/16 , C12M29/04 , C12M47/02
摘要： The invention relates to the use of single- or multilayer plastic web plates in a sloped channel-type solid material separator with a lamella package.
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公开(公告)号：EP2817405B1
公开(公告)日：2016-12-07
申请号：EP13706481.2
申请日：2013-02-20
发明人： PASTOR, Andre , SELETZKY, Juri , BROD, Helmut , KAULING, Joerg , COMMER, Peter
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3.发明公开EINWEG ABSCHEIDER ZUR RÜCKHALTUNG UND RÜCKFÜHRUNG VON ZELLEN 审中-公开EINWEG ABSCHEIDER ZURRÜCKHALTUNGUNDRÜCKFÜHRUNGVON ZELLEN
公开(公告)号：EP2817406A1
公开(公告)日：2014-12-31
申请号：EP13707318.5
申请日：2013-02-20
发明人： KAULING, Joerg , SELETZKY, Juri , MAGNUS, Jorgen , PASTOR, Andre , BROD, Helmut
CPC分类号： C12M33/22 , C12M23/06 , C12M23/14 , C12M23/26 , C12M23/28 , C12M27/16 , C12M29/04 , C12M47/02
摘要： The invention relates to a separator for retaining and recirculating cells in a continuous-flow- or batch-flow-type plastic bag or bottle which can preferably be operated outside of a bioreactor. Additionally, the invention relates to a method for retaining and recirculating cells within or outside of a bioreactor. The invention further relates to a method for producing the separator according to the invention.
摘要翻译： 本发明涉及一种用于在连续流动或间歇流动型塑料袋或瓶子中保留和循环细胞的分离器，其优选可在生物反应器外部操作。 另外，本发明涉及用于在生物反应器内或外部保留和再循环细胞的方法。 本发明还涉及制造根据本发明的分离器的方法。
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4.发明授权
公开(公告)号：EP1337280B1
公开(公告)日：2013-09-04
申请号：EP01990404.4
申请日：2001-11-12
发明人： KAISER, Klaus , KAULING, Joerg , HENZLER, Hans-Jürgen , REMINGTON, Kathryn M. , TRECKMANN, Rolf , GALLOWAY, Cynthia, J.
CPC分类号： B01J19/123 , A23L3/28 , A61K41/0019 , A61L2/0005 , A61L2/0011 , A61L2/10 , A61M1/3681 , A61M1/3683 , A61M2205/053 , B01J19/2405 , B01J2219/00139 , B01J2219/00164 , B01J2219/00168 , C02F1/325 , C02F2201/32 , C02F2201/3223 , C02F2201/328 , Y10S422/905
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5.发明公开
公开(公告)号：EP2342315A2
公开(公告)日：2011-07-13
申请号：EP09778578.6
申请日：2009-09-17
发明人： BROD, Helmut , FRAHM, Björn , KAULING, Joerg
CPC分类号： B01F3/04269 , B01F11/0088 , B01F2003/04319 , B01F2003/04404 , C12M23/24 , C12M27/04 , C12M29/04 , C12M39/00
摘要： The invention relates to a method for reducing deposits during the cultivation of organisms, particularly cell cultures, which tend to agglomerate or adhere to the bioreactor and the elements thereof, or in which cell debris or substances easily agglomerate or adhere.
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6.发明公开VERFAHREN ZUR SELEKTIVEN ABTRENNUNG VON PEPTIDEN UND PROTEINEN MITTELS KRISTALLISATION 审中-公开受理并结晶蛋白质和肽的选择性分离
公开(公告)号：EP2291389A1
公开(公告)日：2011-03-09
申请号：EP09768922.8
申请日：2009-06-16
IPC分类号： C07K1/30
摘要： The invention relates to a method for removing and/or selectively separating peptides and proteins from a solution by means of a controlled crystallization process.
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公开(公告)号：EP2427268A1
公开(公告)日：2012-03-14
申请号：EP09764729.1
申请日：2009-12-03
CPC分类号： B01J19/285 , B01F11/0002 , B01F15/00876 , C12M23/26 , C12M27/10 , G06K19/0716
摘要： The invention relates to a reactor designed as a disposable element, a container for receiving the reactor, a device comprising a reactor, and a drive unit for generating a rotating-oscillating motion of the reactor, and the use of the device for cultivating cells and/or microorganisms.
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公开(公告)号：EP2379694A1
公开(公告)日：2011-10-26
申请号：EP09764744.0
申请日：2009-12-08
发明人： JENNE, Marc , FRAHM, Björn , KAULING, Joerg , BROD, Helmut
CPC分类号： C12M29/08
摘要： The invention relates to a bioreactor, to the use of the bioreactor for culturing microorganisms or cell cultures, and also to a method for culturing microorganisms or cell cultures.
摘要翻译： 本发明涉及生物反应器，涉及生物反应器用于培养微生物或细胞培养物的用途，还涉及用于培养微生物或细胞培养物的方法。
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公开(公告)号：EP2898059A1
公开(公告)日：2015-07-29
申请号：EP13760060.7
申请日：2013-09-13
CPC分类号： C12M23/08 , C12M21/08 , C12M23/22 , C12M23/28 , C12M23/34 , C12M23/38 , C12M23/48 , C12M27/10 , C12M27/14 , C12M29/00 , C12M29/20 , C12M37/00 , C12M37/02 , C12M41/00
摘要： The invention relates to a reactor tank designed as a disposable element, comprising a cover and/or optoelectronically readable sensor patches fastened in the interior, a reactor, comprising the reactor tank and a reactor tank accommodating periphery, which comprises a reactor tank retainer and optionally an optoelectronic measuring system for reading sensor patches, wherein the reactor tank retainer is coupled to a drive unit for producing a rotational oscillating motion of the reactor tank about a center vertical axis of the reactor tank, and the use of said device to cultivate cells and/or microorganisms.
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公开(公告)号：EP2389430A2
公开(公告)日：2011-11-30
申请号：EP10700704.9
申请日：2010-01-13
发明人： KAULING, Joerg , FRAHM, Björn , PÜTZ, Andre , SCHINDLER, Markus
CPC分类号： A61K38/12 , B01F3/04517 , B01F3/04539 , B01F7/1675 , B01F7/18 , B01F11/0002 , C12M29/06
摘要： The invention relates to a novel gassing system that can be used particularly but not exclusively in biotechnology for supplying oxygen to cells or microorganisms. The gassing system comprises a bubble column and a distributor. There is furthermore a fluid medium in the tank that is to be supplied with gas. A vector is used as a transport means for the gas. The gas is incorporated into the bubble column and taken up by the vector here. The vector is applied to the fluid surface in droplet form via the distributor, sinks down into the medium and releases a portion of the absorbed gas to the medium. There is a collection device on the floor of the tank wherein the vector drops coalesce and enter the bubble column again. The invention furthermore relates to a bioreactor comprising the novel gassing system. The invention furthermore relates to a method for gassing a fluid medium, preferably an aqueous suspension comprising cells or microorganisms.
摘要翻译： 本发明涉及一种新颖的放气系统，其可以特别但不专门用于向细胞或微生物供应氧气的生物技术。 充气系统包括泡罩塔和分配器。 此外在储罐中还有流体介质供应气体。 矢量被用作气体的运输工具。 气体被结合到泡沫柱中并被这里的载体吸收。 载体通过分配器以液滴形式施加到流体表面，沉入介质并将一部分吸收的气体释放到介质中。 在坦克的地板上有一个收集装置，其中载体聚结并再次进入泡沫柱。 本发明还涉及包含新型放气系统的生物反应器。 本发明还涉及用于放气流体介质，优选含有细胞或微生物的含水悬浮液的方法。
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