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    OCTAGONAL PILLAR-SHAPED CELL CULTURE CONTAINER
    4.
    发明公开
    OCTAGONAL PILLAR-SHAPED CELL CULTURE CONTAINER 审中-公开

    公开(公告)号：EP3130659A4

    公开(公告)日：2017-12-06

    申请号：EP15776072

    申请日：2015-04-09

    Applicant: ANIMAL STEM CELL

    Inventor： NAGAIKE KAZUHIRO ,  SUZUKI TOSHINORI

    IPC: C12M1/00 ,  C12M1/24

    CPC classification number: C12M23/08 ,  C12M23/20 ,  C12M23/22

    Abstract: The present invention addresses the problem of providing a means, whereby mesenchymal stem cells or adherent cells can be mass-cultured, while monitoring the cell state and strictly maintaining and controlling the same during the course of culture, to obtain cells in an amount as required for treatment of a disease, and can be homogeneously, economically, and efficiently harvested. The present invention also addresses the problem of providing a mass culture container capable of complying with a variety of demands for setting culture conditions; for example, coating of culture surface(s), combination(s) of various types of cells to be adhered to the culture surface(s), and so forth. To resolve these problems, provided is an octagonal-prism-shaped cell culture container having a closed bottom end portion and having an opening for liquid at a top end portion which is mutually opposed thereto, and in which the respective surfaces that form said octagonal prism thereof are planar, being a cell culture container in which mutually opposed pairs of surfaces among the respective surfaces that form said octagonal prism are parallel, and having a structure such that the closed bottom end portion thereof is conical in shape or is in the shape of an octagonal pyramid. The octagonal-prism-shaped cell culture container is usable as a means for homogeneous, economic and efficient mass culture.

    CELL CULTURE MEDIA EXTENDING MATERIALS AND METHODS
    5.
    发明公开
    CELL CULTURE MEDIA EXTENDING MATERIALS AND METHODS 审中-公开
    细胞培养介质延伸材料和方法

    公开(公告)号：EP3224341A1

    公开(公告)日：2017-10-04

    申请号：EP15801660.0

    申请日：2015-11-20

    Applicant: Corning Incorporated

    Inventor： MARTIN, Gregory Roger ,  TANNER, Allison Jean ,  WILKS, Alexander Meyer

    IPC: C12M1/00

    CPC classification number: C12M23/08 ,  C12M23/20 ,  C12N5/0682

    Abstract: This disclosure provides a cell culture media extending material capable of releasing nutrients into the cell culture environment slowly over time. In embodiments, this material is a part of a cell culture vessel. In embodiments, the material is a coating or a film on a surface of a cell culture material. In additional embodiments, the material is a surface upon which cells are cultured, such as a cell culture vessel or a microcarrier.

    Abstract translation: 本公开提供了能够随着时间的推移缓慢释放营养物到细胞培养环境中的细胞培养基延伸材料。 在实施方案中，这种材料是细胞培养容器的一部分。 在实施方案中，该材料是细胞培养材料表面上的涂层或膜。 在另外的实施方案中，材料是培养细胞的表面，例如细胞培养容器或微载体。

    BEAD BEATING TUBE AND METHOD FOR EXTRACTING DEOXYRIBONUCLEIC ACID AND/OR RIBONUCLEIC ACID FROM MICROORGANISMS
    6.
    发明公开
    BEAD BEATING TUBE AND METHOD FOR EXTRACTING DEOXYRIBONUCLEIC ACID AND/OR RIBONUCLEIC ACID FROM MICROORGANISMS 审中-公开
    珠击管和从微生物中提取脱氧核糖核酸和/或核糖核酸的方法

    公开(公告)号：EP3199629A1

    公开(公告)日：2017-08-02

    申请号：EP16153540.6

    申请日：2016-01-30

    Applicant: Safeguard Biosystems Holdings Ltd.

    Inventor： Klapproth, Holger ,  Smit, Nicolaas

    IPC: C12N15/10 ,  C12N1/06 ,  C12Q1/68

    CPC classification number: C12N15/1006 ,  B01L3/5082 ,  B01L2300/042 ,  C12M23/08 ,  C12N1/066 ,  C12Q1/6806 ,  C12Q2523/303 ,  C12Q2527/125 ,  C12Q2527/137

    Abstract: A bead beating tube comprises a sample tube comprising a container member (2) with an inner cavity (3), an aperture (4) for filling a sample fluid potentially containing microorganisms into the inner cavity (3), and a closure for closing the aperture (4). A plurality of macroscopic, mineral particles (7) are arranged in the inner cavity (3) which are adapted to mechanically destroy the cell walls of the microorganisms contained in the sample fluid (5) when the sample fluid is filled into the inner cavity (3) and the bead beating tube is subject to mechanical oscillations. A blocking reagent (8) comprising urea and/or at least one guanidine salt and/or at least one detergent is arranged in dried form in the inner cavity (3) of the sample tube.

    Abstract translation: 珠打浆管包括样品管，该样品管包括具有内腔（3）的容器构件（2），用于将可能含有微生物的样本流体填充到内腔（3）中的孔（4），以及用于关闭 光圈（4）。 在内腔（3）中布置有多个宏观的矿物颗粒（7），当样品流体填充到内腔中时适于机械地破坏样品流体（5）中包含的微生物的细胞壁 3）并且珠子打浆管受到机械振荡。 包含尿素和/或至少一种胍盐和/或至少一种去污剂的封闭剂（8）以干燥形式布置在样品管的内腔（3）中。

    CAP WITH FILTER AND TRANSFER APPARATUS
    8.
    发明公开
    CAP WITH FILTER AND TRANSFER APPARATUS 审中-公开
    带过滤器和传送装置的CAP

    公开(公告)号：EP3173468A1

    公开(公告)日：2017-05-31

    申请号：EP16194336.0

    申请日：2013-12-13

    Applicant: Scientific Plastic Products, Inc.

    Inventor： Ellis, Samuel A. ,  Hingorani, Kishan G.

    IPC: C12M1/24 ,  C12M1/00 ,  B01L3/00

    CPC classification number: B01D35/02 ,  B01D15/165 ,  B01L3/5635 ,  B01L2200/0684 ,  B01L2300/046 ,  B01L2300/0681 ,  C12M23/08 ,  C12M23/38 ,  C12M29/04 ,  C12M47/10

    Abstract: A cap has recess containing a porous frit and a graded porosity filter located so fluid from a container to which the cap is connected passes through the filter and out a spout on the cap. The filter porosity is selected to pass product expressed from cellular organisms grown in growth media inside the container while filtering out debris. A cap vent allows positive pressure in the container ullage to expedite filtering and reduce agitation of the container contents. This is not just a cap with a filter but an enabling tool. This tool enables total design change in many processes from previous thinking, allowing for the maximization of purified material, and reduction of multiple steps.

    Abstract translation: 盖子具有包含多孔玻璃料的凹部以及位于盖子连接到的容器的流体流动的渐变多孔性过滤器，该过滤器穿过过滤器并从盖子上的喷嘴出来。 选择过滤孔隙度以使从容器内生长培养基中生长的细胞生物体表达的产物通过，同时过滤掉碎片。 盖子通风口允许容器空间中的正压力加速过滤并减少容器内容物的搅动。 这不仅仅是一个带有过滤器的帽子，而是一个有利的工具。 这个工具可以使以前的思想在许多过程中发生全面的设计变更，从而实现纯化材料的最大化，并减少多个步骤。

    DEVICE AND METHOD FOR COMPRESSING A HYDROGEL
    9.
    发明公开
    DEVICE AND METHOD FOR COMPRESSING A HYDROGEL 有权
    VORRICHTUNG UND VERFAHREN ZUR VERDICHTUNG EINES HYDROGELS

    公开(公告)号：EP3013381A2

    公开(公告)日：2016-05-04

    申请号：EP14733647.3

    申请日：2014-06-27

    Applicant: Universität Zürich

    Inventor： REICHMANN, Ernst

    IPC: A61L27/38 ,  A61L27/52 ,  A61L27/60 ,  A61F2/10 ,  C12N5/071

    CPC classification number: A61L27/60 ,  A61F2/105 ,  A61L27/3804 ,  A61L27/3813 ,  A61L27/52 ,  A61L2430/34 ,  C12M23/08 ,  C12M23/22 ,  C12M23/48 ,  C12M25/14 ,  C12M25/18 ,  C12N5/0629 ,  C12N2533/90 ,  C12N2537/00

    Abstract: The invention relates to a device and a method for compressing a hydrogel layer(H), wherein a separate piston (600) that is designed to be connected to a second component (400) of the device in a releasable manner in an operating mode of the device, particularly by means of a latching connection, presses along a compression direction (C) against said hydrogel layer (H) residing on a membrane bottom (501) of a graft frame (500) so as to compress the hydrogel layer (H) between the piston (600) and the membrane bottom (501).

    Abstract translation: 本发明涉及一种用于压缩水凝胶层（H）的装置和方法，其中分离的活塞（600）被设计成以可释放的方式连接到装置的第二部件（400） 特别是通过闩锁连接装置，该装置沿着压缩方向（C）压靠在驻留在移植物框架（500）的膜底部（501）上的所述水凝胶层（H）上，以便压缩水凝胶层（H ）在活塞（600）和膜底（501）之间。

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