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1.发明授权TETRAHYDROQUINAZOLINE COMPOUNDS AND THEIR USE IN PREPARING MEDICAMENTS FOR TREATING AND PREVENTING VIROSIS 有权TETRAHYDROCHINAZOLINVERBINDUNGEN和它们在药品生产用于治疗和有毒性防治方案
公开(公告)号：EP2119708B1
公开(公告)日：2013-08-14
申请号：EP08700583.1
申请日：2008-01-03
Inventor： LI, Song , ZHU, Xuejun , ZHAO, Guoming , WANG, Lili , ZHONG, Wu , ZHENG, Zhibing , XIAO, Junhai
IPC: C07D239/72 , A61K31/495 , A61P31/12
CPC classification number: C07D239/74 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D417/04
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2.发明授权NEW SUBSTITUTED PENTABASIC AZAHETEROCYCLIC COMPOUNDS AND ITS USE OF TREATING PROTEIN AGING DISEASE 有权新的取代PENTABASISCHE氮杂杂环化合物及其用途的蛋白质老化疾病的治疗
公开(公告)号：EP1985296B1
公开(公告)日：2012-06-27
申请号：EP07710857.9
申请日：2007-01-29
Inventor： LI, Song , CUI, Hao , XIAO, Junhai , ZHONG, Wu , WANG, Lili , CHENG, Gang
IPC: C07D263/32 , C07D263/52 , C07D277/22 , C07D277/60 , A61K31/421 , A61K31/423 , A61K31/426 , A61K31/428 , A23L3/3544 , A61P3/10 , A61P9/12
CPC classification number: C07D277/62 , A23L3/3526
Abstract: The substituted pentabasic azaheterocyclic compounds of formula I and/or its pharmacological salts and hydrates are provided in the present invention, the groups in the formula are defined as the description. The medicinal composition comprising above-mentioned compounds and/or its pharmacological salts and hydrates is also provided, and the application of the said medicinal composition in preparing medicines for preventing or treating the diseases related with AGEs, and in preparing oral preparation for inhibiting or reversing discoloration of teeth, and in preparing antistaling agent of animals and plants protein are disclosed.
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3.发明授权NEW DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN MANUFACTURES OF PHARMACEUTICAL MEDICAMENTS FOR TREATMENT AND PREVENTION AGAINST VIROSIS 有权新DIHYDROPYRMIDINVERBINDUNGEN和它们在药品生产用于治疗和有毒性防治方案
公开(公告)号：EP2135866B1
公开(公告)日：2014-07-02
申请号：EP08700582.3
申请日：2008-01-03
Inventor： LI, Song , ZHU, Xuejun , ZHAO, Guoming , WANG, Lili , ZHONG, Wu , ZHENG, Zhibing , XIAO, Junhai
IPC: C07D405/04 , C07D409/04 , A61P1/16 , A61K31/496
CPC classification number: C07D409/04 , C07D405/04
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4.发明公开OPTICAL PURE DIHYDROPYRIMIDINE COMPOUNDS, THEIR USES IN THE MANUFACTURE OF A MEDICAMNENT FOR THE TREATMENT OR THE PREVENTION OF VIROSIS DISEASES 有权光学纯DIHYDROPYRIMIDINVERBINDUNGEN及其用在药物中的用途，用于治疗或预防VIROSEKRANKHEITEN的
公开(公告)号：EP2048141A1
公开(公告)日：2009-04-15
申请号：EP07764007.6
申请日：2007-07-09
Inventor： LI, Song , XIA, Guangqiang , ZHAO, Guoming , WANG, Lili , ZHENG, Zhibing , XIE, Yunde , ZHONG, Wu , XIAO, Junhai , LI, Xingzhou , CUI, Hao
IPC: C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D417/04 , C07D417/14 , A61K31/4164 , A61K31/427 , A61K31/44 , A61K31/20
CPC classification number: C07D417/04 , C07D239/20 , C07D239/28
Abstract: The present invention relates to an optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, a process for preparing the optically pure compound of formula (I), and use of the optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof as a medicament, in particular as a medicament for the treatment and prevention of type B hepatitis.
Abstract translation: 本发明涉及式（I）或其药学上可接受的盐或水合物，其用于制备式（I）的光学纯的化合物的方法，以及使用式（I）的光学纯的化合物的光学纯的化合物或 药学上可接受的盐或水合物作为药物，特别是作为用于B型肝炎的治疗和预防药物。
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5.发明公开TYROSINE DERIVATIVES SUBSTITUTED BY N-PHENYLACRYLOYL AS AGONISTS OF HPPAR ALPHA AND HPPAR GAMA 有权N-苯基丙烯酸酯类化合物与HPPAR-GAMMA
公开(公告)号：EP1757596A1
公开(公告)日：2007-02-28
申请号：EP05714787.8
申请日：2005-03-02
Inventor： LI, Song , ZHOU, Xinbo , WANG, Lili , XU, Cheng , RUAN, Chengmai , LIN, Cuifang , XIAO, Junhai , ZHENG, Zhibing , LIU, Hongying , XIE, Yunde , ZHONG, Wu , CUI, Hao
IPC: C07D263/32 , A61K31/421 , A61P3/10 , A61P9/00
CPC classification number: C07D263/32 , C07D413/12
Abstract: The present invention relates to a compound of formula I, racemates, optically active isomers, or pharmaceutically acceptable salts or solvates thereof, and a pharmaceutical composition comprising the compound, the various radicals in the formula I are the same as defined in the claims. The present invention also relates to a process for preparing the compound of formula I and use of said compound in the preparation of a medicament for the treatment of hyperglycemia, dyslipidemia, type II diabetes mellitus including associated diabetic dyslipidemia
Abstract translation: 本发明涉及式I化合物，外消旋体，旋光异构体或其药学上可接受的盐或溶剂化物，以及包含该化合物的药物组合物，式I中的各种基团与权利要求中所定义的相同。 本发明还涉及制备式I化合物的方法和所述化合物在制备用于治疗高血糖，血脂异常，II型糖尿病的药物中的用途，所述II型糖尿病包括相关的糖尿病性血脂异常
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Patent Agency Ranking6.发明授权THIAZOLIUM SALT COMPOUND AND ITS USE FOR TREATING PROTEIN AGING ASSOCIATED DISEASES 有权THIAZOLIUMSALZVERBINDUNG及其用于疾病治疗的蛋白质老化有关
公开(公告)号：EP2341048B1
公开(公告)日：2013-03-06
申请号：EP09813969.4
申请日：2009-09-15
Inventor： LI, Song , ZHONG, Wu , WANG, Lili , ZHENG, Zhibing , CUI, Hao , XIAO, Junhai , CHENG, Gang , XIE, Yunde , ZHANG, Bing
IPC: C07D277/22 , A61K31/426 , A61P3/10 , A61P9/12 , A61P9/14 , A61P9/10 , A61P27/12 , A61P25/02 , A61P19/02 , A61Q11/00
CPC classification number: C07D277/22 , A61K8/49 , A61K31/426 , A61Q11/00 , A61Q19/08
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7.发明授权DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDICAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES 有权DIHYDROPYRIMIDINVERBINDUNGEN及其用途毒品生产用于治疗和预防疾病的抗病毒
公开(公告)号：EP2039686B1
公开(公告)日：2012-02-29
申请号：EP07764006.8
申请日：2007-07-09
Inventor： LI, Song , ZHAO, Guoming , XIA, Guangqiang , WANG, Lili , ZHENG, Zhibing , XIE, Yunde , ZHONG, Wu , XIAO, Junhai , LI, Xingzhou , CUI, Hao
IPC: C07D417/04 , A61K31/506 , A61P31/12 , A61P1/16
CPC classification number: C07D239/20 , C07D403/04 , C07D417/04
Abstract: Compounds of formula I, their pharmaceutically acceptable salts or hydrates. Preparation methods of compounds of formula I and uses of compounds of formula I or their pharmaceutically acceptable salts or hydrates in preparation of medicaments, especially for treating and preventing hepatitis B agents.
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8.发明公开THIAZOLIUM SALT COMPOUND AND THE USE OF TREATING THE PROTEIN AGING DISEASE 有权THIAZOLIUMSALZVERBINDUNG及其用于疾病治疗的蛋白质老化有关
公开(公告)号：EP2341048A1
公开(公告)日：2011-07-06
申请号：EP09813969.4
申请日：2009-09-15
Inventor： LI, Song , ZHONG, Wu , WANG, Lili , ZHENG, Zhibing , CUI, Hao , XIAO, Junhai , CHENG, Gang , XIE, Yunde , ZHANG, Bing
IPC: C07D277/22 , A61K31/426 , A61P3/10 , A61P9/12 , A61P9/14 , A61P9/10 , A61P27/12 , A61P25/02 , A61P19/02 , A61Q11/00
CPC classification number: C07D277/22 , A61K8/49 , A61K31/426 , A61Q11/00 , A61Q19/08
Abstract: The present invention relates to a composition of a thiazolium compound of formula I or a solvate thereof, wherein the definitions of groups in the formula I are as those given in the claims:
Abstract translation: 本发明涉及式的噻唑鎓化合物的组合物I或它们的溶剂合物，worin基团的定义中的式I的那些在权利要求中给出：
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9.发明公开DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDICAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES 有权DIHYDROPYRIMIDINVERBINDUNGEN及其用途毒品生产用于治疗和预防疾病的抗病毒
公开(公告)号：EP2039686A1
公开(公告)日：2009-03-25
申请号：EP07764006.8
申请日：2007-07-09
Inventor： LI, Song , ZHAO, Guoming , XIA, Guangqiang , WANG, Lili , ZHENG, Zhibing , XIE, Yunde , ZHONG, Wu , XIAO, Junhai , LI, Xingzhou , CUI, Hao
IPC: C07D239/20 , C07D403/04 , C07D417/04 , A61K31/505 , A61K31/506 , A61P31/12 , A61P1/16
CPC classification number: C07D239/20 , C07D403/04 , C07D417/04
Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, to a process for preparing the compound of formula (I), and to use of the compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof as a medicament, in particular as a medicament for the treatment and prevention of type B hepatitis.
Abstract translation: 本发明涉及式（I）或其药学上可接受的盐或其水合物的化合物，一种用于制备式（I）的化合物，以及使用式（I）的化合物或其药学上可接受的盐的 或其水合物作为药物，特别是作为用于B型肝炎的治疗和预防药物。
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10.发明授权OPTICALLY PURE DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES FOR THE PREPARATION OF A MEDICAMENT FOR TREATMENT AND PREVENTION OF VIRAL DISEASES. 有权光学纯二氢嘧啶化合物及其在制备用于治疗和预防病毒疾病的药物中的用途。
公开(公告)号：EP2048141B1
公开(公告)日：2017-06-14
申请号：EP07764007.6
申请日：2007-07-09
Inventor： LI, Song , XIA, Guangqiang , ZHAO, Guoming , WANG, Lili , ZHENG, Zhibing , XIE, Yunde , ZHONG, Wu , XIAO, Junhai , LI, Xingzhou , CUI, Hao
IPC: C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D417/04 , C07D417/14 , A61K31/4164 , A61K31/427 , A61K31/44 , A61K31/20 , A61P31/12 , C07D239/20 , A61K31/506
CPC classification number: C07D417/04 , C07D239/20 , C07D239/28
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