公开(公告)号：EP4113121A1

公开(公告)日：2023-01-04

申请号：EP21760161.6

申请日：2021-01-18

申请人： Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. ,  Xiamen University

发明人： LI, Tingdong ,  SHI, Qiaoyun ,  REN, Jinkai ,  GE, Shengxiang ,  HONG, Congming ,  ZHANG, Xiaolei ,  WANG, Dong ,  ZHOU, Guoliang ,  YUAN, Quan ,  WU, Xiaowei ,  WANG, Xuan ,  WU, Yangtao ,  PAN, Haifeng ,  QI, Yuting ,  JIA, Xuerong ,  ZHOU, Lizhi ,  HOU, Wangheng ,  QIAO, Shan ,  LI, Shaowei ,  ZHANG, Jun ,  XIA, Ningshao

IPC分类号： G01N33/68 ,  G01N33/569 ,  G01N33/558 ,  C12N15/867 ,  C12N15/65 ,  C07K14/165

摘要： Provided are a method for assaying a specific IgM antibody and a total antibody for the 2019 novel coronavirus (2019-nCOV), a method for determining whether subjects are infected with 2019-nCOV, and a virus antigen and a kit for carrying out the above-mentioned detection.

公开(公告)号：EP4144765A1

公开(公告)日：2023-03-08

申请号：EP21797718.0

申请日：2021-04-30

申请人： Yang Sheng Tang Company, Ltd. ,  Xiamen University

发明人： ZHANG, Yali ,  WANG, Shaojuan ,  WU, Yangtao ,  HOU, Wangheng ,  YE, Jianghui ,  WANG, Juan ,  ZHANG, Tianying ,  CHENG, Tong ,  YUAN, Quan ,  XIA, Ningshao

IPC分类号： C07K19/00 ,  C12N15/62 ,  G01N33/58

摘要： Disclosed are a fusion protein probe and a cell model for screening a blocking agent of coronavirus infections, a screening system comprising same, and a method of using the screening system for screening a blocking agent of coronavirus infections. The screening system and method do not involve live viruses, are simple and convenient to operate, have a high accuracy, are suitable for high throughput screening, and are of great significance for the development of coronavirus neutralizing antibodies, preventive vaccines, and small molecule drugs.