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公开(公告)号:EP2768843B1
公开(公告)日:2017-08-30
申请号:EP12841318.4
申请日:2012-10-19
发明人: LIAO, Jiali , OLECH, Lee , CHEN, Hong , HE, Xuemei , FROST, Russell
CPC分类号: B01J39/26 , C07K1/165 , C07K1/22 , C07K16/065
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公开(公告)号:EP4025336A1
公开(公告)日:2022-07-13
申请号:EP20860236.7
申请日:2020-09-04
发明人: BELISLE, Christopher , HE, Xuemei , CHEN, Hong , XU, Yueping , LIAO, Jiali
IPC分类号: B01J20/26
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公开(公告)号:EP3001833A1
公开(公告)日:2016-04-06
申请号:EP15790812.0
申请日:2015-06-24
发明人: BERKELMAN, Tom , LIAO, Jiali
IPC分类号: B82Y15/00 , C07K16/00 , G01N33/53 , G01N33/531
CPC分类号: G01N33/533 , A61K47/6929 , C07K1/34 , C07K16/00 , G01N33/54346
摘要: Methods of purifying antibody-nanoparticle conjugates with size exclusion chromatography are provided.
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公开(公告)号:EP4308176A1
公开(公告)日:2024-01-24
申请号:EP22772180.0
申请日:2022-03-17
发明人: BELISLE, Christopher , LIAO, Jiali , LOZANO, Edwin
IPC分类号: A61K49/00 , C07D241/12 , C07D241/20
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公开(公告)号:EP2822687B1
公开(公告)日:2019-11-27
申请号:EP13758660.8
申请日:2013-03-05
发明人: LIAO, Jiali , FROST, Russell
IPC分类号: B01D15/32
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公开(公告)号:EP3519351A1
公开(公告)日:2019-08-07
申请号:EP17857258.2
申请日:2017-09-25
发明人: LIAO, Jiali , BERKELMAN, Tom
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公开(公告)号:EP3762120A1
公开(公告)日:2021-01-13
申请号:EP19764738.1
申请日:2019-03-08
发明人: BELISLE, Christopher , CHEN, Hong , XU, Yueping , LIAO, Jiali , HE, Xuemei
IPC分类号: B01D15/26 , B01D15/36 , B01J20/281 , B01J41/20
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公开(公告)号:EP3519070A1
公开(公告)日:2019-08-07
申请号:EP17857257.4
申请日:2017-09-25
发明人: LIAO, Jiali , BELISLE, Christopher
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公开(公告)号:EP2768843A1
公开(公告)日:2014-08-27
申请号:EP12841318.4
申请日:2012-10-19
发明人: LIAO, Jiali , OLECH, Lee , CHEN, Hong , HE, Xuemei , FROST, Russell
CPC分类号: B01J39/26 , C07K1/165 , C07K1/22 , C07K16/065
摘要: Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix.
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