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公开(公告)号：EP3954383A1
公开(公告)日：2022-02-16
申请号：EP21191307.4
申请日：2016-02-09
申请人： BioNTech SE , TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ GGMBH
发明人： SAHIN, Ugur , LÖWER, Martin , TADMOR, Arbel D. , BOEGEL, Sebastian , SCHRÖRS, Barbara , VORMEHR, Mathias , KREITER, Sebastian
摘要： The present invention relates to methods for predicting T cell epitopes useful for vaccination. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic and, in particular, useful for vaccination, or for predicting which of such modifications are most immunogenic and, in particular, most useful for vaccination. The methods of the invention may be used, in particular, for the provision of vaccines which are specific for a patient's tumor and thus, in the context of personalized cancer vaccines.
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公开(公告)号：EP3946425A1
公开(公告)日：2022-02-09
申请号：EP20718248.6
申请日：2020-04-02
申请人： BioNTech SE , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
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公开(公告)号：EP4262857A1
公开(公告)日：2023-10-25
申请号：EP21840027.3
申请日：2021-12-20
申请人： BioNTech SE
IPC分类号： A61K39/00
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公开(公告)号：EP4262821A1
公开(公告)日：2023-10-25
申请号：EP21840031.5
申请日：2021-12-20
申请人： BioNTech SE
发明人： SAHIN, Ugur , MUIK, Alexander , KRANZ, Lena Mareen , VORMEHR, Mathias , FELLERMEIER-KOPF, Sina , DIEKMANN, Jan , EISEL, David
IPC分类号： A61K31/7105 , A61K38/20 , C07K14/54 , C07K14/55 , C07K14/765 , C12N15/62
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公开(公告)号：EP4100049A1
公开(公告)日：2022-12-14
申请号：EP21704436.1
申请日：2021-02-02
申请人： BioNTech SE
发明人： SAHIN, Ugur , MUIK, Alexander , KRANZ, Lena , VORMEHR, Mathias
IPC分类号： A61K39/00 , C07K16/28 , C07K14/705 , A61K39/395
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公开(公告)号：EP4411376A2
公开(公告)日：2024-08-07
申请号：EP24171718.0
申请日：2017-05-10
申请人： BioNTech SE , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
IPC分类号： G01N33/53
CPC分类号： G01N33/5308 , G01N33/6878 , G01N33/6887 , G01N2333/471220130101 , G01N2800/5220130101 , G01N33/5035 , A61P35/04
摘要： The present invention relates to methods for predicting peptides or polypeptides such as T cell epitopes useful for immunotherapy such as for vaccination. In particular, the present invention relates to methods for predicting whether peptides or polypeptides such as tumor-associated antigens or epitopes, in particular tumor-associated neoantigens or neoepitopes, are immunogenic and, in particular, useful for immunotherapy such as for vaccination. The methods of the invention may be used, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.
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公开(公告)号：EP4034149A1
公开(公告)日：2022-08-03
申请号：EP20772086.3
申请日：2020-09-22
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