-
公开(公告)号:EP4335444A3
公开(公告)日:2024-06-26
申请号:EP23211804.2
申请日:2018-01-17
申请人: BioNTech SE , University Of Verona
IPC分类号: C12N5/0786 , A61K35/15 , A61K35/28 , C07K14/435 , C12N5/0775 , A61K48/00 , A61K35/12
CPC分类号: A61K48/00 , A61K35/28 , C12N5/0645 , C12N5/0663 , A61K2035/12220130101 , A61K2035/12420130101 , C12N2510/0020130101 , C07K14/4702 , A61K39/461 , A61K39/4621 , A61K39/4614 , A61K2239/3120230501 , A61K39/4622 , A61K2239/3820230501 , A61K39/46434
摘要: The present invention relates to cells which are engineered so as to increase the cellular level of cellular FLICE [Fas-associated death domain (FADD)-like IL-1β-converting enzyme]-inhibitory protein (CFLAR). The engineered cells have the ability to induce tolerance. Enhanced tolerogenicity is useful for prolonging survival of a foreign transplant and for treatment of autoimmune diseases.
-
公开(公告)号:EP3571296A1
公开(公告)日:2019-11-27
申请号:EP18701425.3
申请日:2018-01-17
申请人: Biontech SE , University Of Verona
IPC分类号: C12N5/0786 , A61K35/15 , A61K35/28 , C07K14/435 , C12N5/0775 , A61K48/00 , A61K35/12
-
公开(公告)号:EP4335444A2
公开(公告)日:2024-03-13
申请号:EP23211804.2
申请日:2018-01-17
申请人: BioNTech SE , University Of Verona
IPC分类号: A61K35/12
摘要: The present invention relates to cells which are engineered so as to increase the cellular level of cellular FLICE [Fas-associated death domain (FADD)-like IL-1β-converting enzyme]-inhibitory protein (CFLAR). The engineered cells have the ability to induce tolerance. Enhanced tolerogenicity is useful for prolonging survival of a foreign transplant and for treatment of autoimmune diseases.
-
公开(公告)号:EP4444342A1
公开(公告)日:2024-10-16
申请号:EP22834951.0
申请日:2022-12-08
申请人: BioNTech SE
-
公开(公告)号:EP4413040A1
公开(公告)日:2024-08-14
申请号:EP22802904.7
申请日:2022-10-05
申请人: Genmab A/S , BioNTech SE
发明人: MUIK, Alexander , NÜRMBERGER, Kristina , PENCHEVA, Nora , JURE-KUNKEL, Maria,N, , SAHIN, Ugur , FELLERMEIER-KOPF, Sina , GARRIDO CASTRO, Patricia , BLUM, Jordan , GIESEKE, Friedericke , BREIJ, Esther C. W. , GUELEN, Lars , NEIJSSEN, Joost , BECKMANN, Karsten , PAULMANN, Claudia , DE KREUK, Bart-Jan , HIBBERT, Richard , SCHUURMAN, Janine , LABRIJN, Aran , KUZMANOV, Ivan
-
公开(公告)号:EP4370551A1
公开(公告)日:2024-05-22
申请号:EP22750715.9
申请日:2022-07-13
申请人: BioNTech SE
发明人: SAHIN, Ugur , STADLER, Christiane , LINDEMANN, Claudia , ELLINGHAUS, Ursula , BÄHR-MAHMUD, Hayat , FISCHER, Leyla , CHATURVEDI, Anuhar , BOROS, Gábor , REINHOLZ, Jonas , BESSONOV, Sergey , KARIKÓ, Katalin
CPC分类号: C07K16/2809 , C07K16/28 , C07K2317/3120130101 , A61P35/00 , C07K2317/62220130101
-
公开(公告)号:EP4359435A1
公开(公告)日:2024-05-01
申请号:EP22735846.2
申请日:2022-06-20
申请人: Genmab A/S , BioNTech SE
发明人: SAHIN, Ugur , MUIK, Alexander , FORSSMANN, Ulf , JURE-KUNKEL, Maria N. , BAJAJ, Gaurav , TALHAUSER, Craig , PENCHEVA, Nora
CPC分类号: C07K16/24 , C07K16/2827 , A61K2039/54520130101 , C07K2317/73420130101
-
公开(公告)号:EP4326317A1
公开(公告)日:2024-02-28
申请号:EP22720733.9
申请日:2022-04-20
申请人: BioNTech SE
发明人: SAHIN, Ugur , MUIK, Alexander
-
公开(公告)号:EP4162034A1
公开(公告)日:2023-04-12
申请号:EP21729331.5
申请日:2021-06-01
申请人: BioNTech SE , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
发明人: PERKOVIC, Mario , WITZEL, Sonja , BEISSERT, Tim , SAHIN, Ugur
-
公开(公告)号:EP4138897A1
公开(公告)日:2023-03-01
申请号:EP21720413.0
申请日:2021-04-16
申请人: BioNTech SE
-
-
-
-
-
-
-
-
-