利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

17 条记录 (耗时 0.019 秒)

    SELECTION AND USE OF MELATONIN SUPPORTING BACTERIA TO REDUCE INFANTILE COLIC
    3.
    发明公开
    SELECTION AND USE OF MELATONIN SUPPORTING BACTERIA TO REDUCE INFANTILE COLIC 审中-公开

    公开(公告)号：EP4086359A1

    公开(公告)日：2022-11-09

    申请号：EP22165915.4

    申请日：2019-07-24

    申请人： Biogaia AB

    发明人： ROOS, Stefan ,  MÖLLSTAM, Bo

    IPC分类号： C12R1/225

    摘要： The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject. Preferred strains for such uses are capable of producing or inducing the production of adenosine. Therapeutic uses of such strains include the treatment or prevention of diseases associated with melatonin deficiency, for example infantile colic. Novel strains are also provided.

    SEROTONIN PRODUCING BACTERIA
    5.
    发明公开
    SEROTONIN PRODUCING BACTERIA 审中-公开

    公开(公告)号：EP4253571A3

    公开(公告)日：2023-12-13

    申请号：EP23186579.1

    申请日：2020-11-06

    申请人： Biogaia AB

    发明人： GRASSET, Estelle ,  KHAN, Muhammad ,  MÖLLSTAM, Bo ,  ROOS, Stefan

    IPC分类号： A61P25/00 ,  A23L33/135 ,  A61K35/747 ,  C12N1/20 ,  C12R1/225 ,  C12R1/25

    摘要： The invention relates to selection of bacterial strain for use in treating a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.

    GOS PRE-CONDITIONING L. REUTERI AND GOS IN FINAL FORMULATION
    10.
    发明公开
    GOS PRE-CONDITIONING L. REUTERI AND GOS IN FINAL FORMULATION 审中-公开

    公开(公告)号：EP4056052A1

    公开(公告)日：2022-09-14

    申请号：EP21162450.7

    申请日：2021-03-12

    申请人： Biogaia AB

    发明人： ROOS, Stefan ,  HORCAJADA, Marie Noëlle ,  BONNET, Nicolas ,  SABATIER, Magalie ,  BOURQUI, Bertrand ,  PRIOULT, Guénolée Eliane Marie ,  DE BRUYN, Florac

    IPC分类号： A23L33/135 ,  A23L33/125

    摘要： The invention herein relates generally to enhancing the survival and activity of probiotic Lactobacillus reuteri strains in mammals by pre-conditioning L. reuteri with GOS during cultivation and to a surprisingly high synbiotic effect of such a pre-conditioned probiotic L. reuteri strain when administered together with GOS further added in the composition. The invention therefore comprises methods for cultivating and manufacturing probiotic L. reuteri strains, and preparing products containing such pre-conditioned strains in combination with additional amounts of GOS. In more detail the present invention relates to a composition comprising a probiotic L. reuteri strain, obtained by a step of growing the bacteria in a medium comprising GOS ("pre-conditioning"), and administering the pre-conditioned bacteria together with further GOS in the final product. The inventors have found that such method induces surprisingly high and unexpected synbiotic beneficial effects of the probiotic bacteria in the gastrointestinal tract. The composition also induces an increased calcium and iron solubility.