公开(公告)号：EP2804700A4

公开(公告)日：2015-10-14

申请号：EP12866245

申请日：2012-12-13

申请人： NOLATO SILIKONTEKNIK AB

发明人： NILSSON TORE

IPC分类号： B01F15/02 ,  B01F5/00 ,  B05C5/02 ,  B05C9/06 ,  B05C11/10 ,  F16J15/10 ,  F16J15/14 ,  H05K9/00

CPC分类号： B05C5/0241 ,  B01F15/0237 ,  B01F2005/0031 ,  B05C5/02 ,  B05C9/06 ,  F16J15/108 ,  F16J15/14

公开(公告)号：EP1086143B1

公开(公告)日：2005-08-24

申请号：EP99915632.6

申请日：1999-03-17

申请人： SIEMENS AKTIENGESELLSCHAFT

发明人： PYSALL, Detlev ,  WACHSEN, Olaf ,  BAYER, Thomas ,  WULF, Stefan

IPC分类号： C08F2/00 ,  B01J19/24 ,  C08F2/06 ,  B01J19/00 ,  C08F20/12

CPC分类号： B01F13/0059 ,  B01F5/0403 ,  B01F2005/0031 ,  B01F2015/062 ,  B01F2215/0049 ,  B01J19/0093 ,  B01J19/242 ,  B01J2219/00889 ,  B29K2105/0002

摘要： Two reaction partners (educts) are stored in separate receptacles (2, 3, 4, 5) and are pumped at an overpressure to a micromixer (18) via warmed heat exchangers (11) using regulating and dosing devices (6, 7) such as dosing pumps. The educts are respectively separated and heated inside the heat exchangers (11, 12) in such a way that the required reaction temperature is immediatedly attained in the micromixer (18) during the mixing process. Polymerization occurs downstream in a tubular reactor (20) that is made of series-mounted tubes (21, 22, 23).

公开(公告)号：EP1380337A3

公开(公告)日：2004-06-16

申请号：EP03015457.9

申请日：2003-07-09

申请人： Tosoh Corporation

发明人： Futami, Toru ,  Ohkawa, Tomohiro ,  Oikawa, Tomoyuki ,  Kawai, Akira ,  Katayama, Koji ,  Nishizawa, Keiichiro

IPC分类号： B01J19/00 ,  B01F13/00

CPC分类号： B01J19/0093 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01F2005/0088 ,  B01F2215/0409 ,  B01F2215/0427 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/086

摘要： A fine channel device comprising a fine channel (19) provided with at least two inlet ports (11, 28, 29) for feeding fluid, inlet channels communicated with the inlet ports, a confluent portion (37) communicated with the inlet channels to feed the fluid, a branch portion (4) communicated with the fine channel, from which at least two outlet channels are branched to feed predetermined amounts of fluid, and outlet ports (12, 30, 31) communicated with the outlet channels, wherein the fine channel (19) is provided with a plurality of partition walls (22) along a boundary formed by at least two kinds of fluid (13, 14) fed from the inlet ports so as not to cause mutual contamination of fluid, whereby different kinds of fluid flowing in the fine channel in an adjacent state can form stably the fluid boundary and each kind of fluid can be discharged from a predetermined outlet port separately without causing the mutual contamination of fluid between adjacent flows of the fluid, is provided. By using such fine channel device, a chemical reaction can be accelerated by making two different kinds of fluid contact at the fluid boundary in a flowing direction of fluid in the fine channel of the fine channel device.

摘要翻译： 一种精细通道装置，其包括：精细通道（19），其设有至少两个用于供给流体的入口端口（11,28,29）;与入口端口连通的入口通道;汇合部分（37），其与入口通道连通以供给 所述流体，与所述精细通道连通的分支部分（4），至少两个出口通道从所述分支部分（4）分支以供给预定量的流体，以及与所述出口通道连通的出口端口（12,30,31） 通道19沿着由从入口供给的至少两种流体13,14形成的边界设置有多个分隔壁22，从而不会引起流体的相互污染， 在相邻状态的微细流路中流动的流体能够稳定地形成流体边界，并且能够将各种流体分别从规定的流出口排出，而不会导致相邻的流体流之间的流体的相互污染。 通过使用这样的微细流路装置，通过使两种不同的流体在细流路装置的微细流路内的流体的流动方向上的流体边界接触，能够促进化学反应。

公开(公告)号：EP0897316B1

公开(公告)日：2003-03-12

申请号：EP97916562.8

申请日：1997-04-15

申请人： CENTRAL RESEARCH LABORATORIES LIMITED

发明人： HARPER, Michael, Jonathan

IPC分类号： B01D11/04 ,  G01N1/40

CPC分类号： G01N1/34 ,  B01D11/0415 ,  B01D11/0453 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00907 ,  B01J2219/00995 ,  G01N2001/4061

摘要： Apparatus for carrying out a process between first and second immiscible fluids comprises channels defining first and second primary flow paths for permitting fluid flow of the respective first and second fluids therethrough. Portions of the flow paths are disposed close to or adjacent one another and communicate with one another at a region where the flow paths are constructed and arranged so as to permit the fluids to form a stable interface between them. At least one of the fluids is induced to flow in a secondary direction perpendicular to the direction of its primary flow path at the region either by bending the primary flow path around a curve, or by positioning flow detectors within the flow path.

公开(公告)号：EP1839738A1

公开(公告)日：2007-10-03

申请号：EP07006539.6

申请日：2007-03-29

申请人： FUJIFILM Corporation

发明人： Ueyama, Tomohide ,  Nagasawa, Hideharu ,  Ichikawa, Yasunori

IPC分类号： B01J19/00 ,  B01F13/00

CPC分类号： B01J19/0093 ,  B01F13/0059 ,  B01F2005/0031 ,  B01J2219/00783 ,  B01J2219/00844 ,  B01J2219/00889

摘要： According to the fluid manipulating method of an aspect of the present invention, since the fluids (L1, L2) can be rectified early by increasing the pressure loss of each, the rectifying area before the joining of the plurality of kinds of fluids can be shortened. Therefore, a plurality of kinds of fluids(L1, L2) can be uniformly reacted or mixed with one another in a stable multiple laminar flow state, and the size of devices (10, 50) can be reduced with the range of applicable flow rates expanded.

摘要翻译： 。根据本发明的一个方面的流体操纵方法中，由于流体（L1，L2）可以通过增加每个的压力损失初期整流，种类的流体的多个接合之前整流区域可以缩短 ， 因此，种类的流体（L1，L2）中的多元性可均匀地反应，或者彼此在一个稳定的多重层流状态，并且设备的尺寸混合（10，50）可以与适用的流速的范围内降低 扩大。

公开(公告)号：EP1415708A2

公开(公告)日：2004-05-06

申请号：EP03024900.7

申请日：2003-10-31

申请人： Hitachi, Ltd.

发明人： Tadashi Sano c/o Hitachi,Ltd.Intell Property Gp

IPC分类号： B01J19/00 ,  B01D11/04 ,  B01F13/00

CPC分类号： B01F13/0062 ,  B01F3/0807 ,  B01F5/0453 ,  B01F5/0682 ,  B01F13/0066 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00837 ,  B01J2219/0084 ,  B01J2219/00891 ,  B01J2219/00923 ,  B01L3/5027 ,  B01L2200/0636 ,  G01N35/08 ,  Y10T137/2224 ,  Y10T137/2564 ,  Y10T436/255

摘要： In a chemical reactor (50), a gas and a liquid which are in trace volumes are used to produce air bubbles and thus increase the interface area between the gas and liquid, substantially enhancing the efficiency of reaction between the gas and liquid. The chemical reactor comprises the following: a sheath flow forming block (10) which forms a plurality of alternating sheath flows with two mutually unmixable fluids (61, 62), a plurality of inlet ports (1, 2) through which the two fluids (61, 62) flow into the sheath flow forming block (10), a contraction zone (11) which simultaneously contracts a plurality of sheath flows formed in the sheath flow forming block (10), and reaction flow channels (21, 22) each of which is connected with the contraction zone (11) and is smaller in width than the sheath flow forming block (10).

摘要翻译： 化学反应器（50）包括鞘流形成块（10），其与两个相互不可混合的流体形成交替的鞘流，用于使鞘流动形成块中的两种流体流动的入口（2），同时收缩的收缩区 形成在成形块中的护套流路和与收缩区域连接并且比鞘流形成块体宽度小的反应流路（21,22）。 还包括用于单独设备的独立权利要求，该装置包括用于流动具有界面的液体的流动通道，用于至少一种液体的第一出口，以及具有设置在第一出口和流动通道之间的孔的分离部分。

公开(公告)号：EP0787029B1

公开(公告)日：1999-01-07

申请号：EP95934714.7

申请日：1995-10-20

申请人： CENTRAL RESEARCH LABORATORIES LIMITED

发明人： SHAW, John, Edward, Andrew ,  SIMPSON, Richard, Iain ,  BULL, Adrian, James ,  SIMPER, Adrian, Mark ,  HOLMES, Robert, George, Godfrey

IPC分类号： B01D11/04 ,  B01D61/28 ,  G01N1/40

CPC分类号： G01N1/4005 ,  B01D11/0403 ,  B01D11/0407 ,  B01D11/0415 ,  B01D11/0419 ,  B01D11/0426 ,  B01D11/043 ,  B01D11/0453 ,  B01D11/0496 ,  B01D61/246 ,  B01D61/28 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00833 ,  B01J2219/00844 ,  B01J2219/00853 ,  B01J2219/00907 ,  B01J2219/00995 ,  G01N1/34 ,  G01N25/14 ,  G01N27/44743 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2001/4016

摘要： PCT No. PCT/GB95/02488 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Oct. 20, 1995 PCT Pub. No. WO96/12540 PCT Pub. Date May 2, 1996In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the liquids without mixing, a method and an apparatus are disclosed and have first and second flow paths carrying first and second immiscible fluids on opposite sides of a foraminous sheet. The height of the apertures in the sheet is not greater than 200 micrometers (measured perpendicular to the width of the sheet and to the direction of fluid flow), and a stable interface is formed between the fluids within each aperture with a significant amount of fluid flow immediately adjacent the interface. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the region without mixing. The width of the flow paths measured perpendicular to sheet lies between 10 and 500 micrometers. The walls of each aperture may be parallel or tapered.

公开(公告)号：EP0839318A1

公开(公告)日：1998-05-06

申请号：EP96925261.0

申请日：1996-06-14

申请人： University of Washington

发明人： YAGER, Paul ,  BRODY, James, P. ,  HOLL, Mark, R. ,  FORSTER, Fred, K. ,  GALAMBOS, Paul, C.

IPC分类号： B01D11 ,  B01D43 ,  B01F13 ,  B01J19 ,  G01N1 ,  G01N15 ,  G01N30 ,  G01N37 ,  G01N35

CPC分类号： B01D11/0492 ,  B01D11/0496 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01J2219/00952 ,  B01J2219/0097 ,  B01J2219/00995 ,  G01N15/06 ,  G01N30/0005 ,  G01N2001/4072 ,  G01N2035/00237 ,  Y10S366/01 ,  Y10T436/255

摘要： This invention provides a microfabricated extraction system and methods for extracting desired particles from a sample stream containing desired and undesired particles. The sample stream is placed in laminar flow contact with an extraction stream under conditions in which inertial effects are negligible. The contact between the two streams is maintained for a sufficient period of time to allow differential transport of the desired particles from the sample stream into the extraction stream. In a preferred embodiment the differential transport mechanism is diffusion. The extraction system of this invention coupled to a microfabricated diffusion-based mixing device and/or sensing means allows picoliter quantities of fluid to be processed or analyzed on devices no larger than silicon wafers.

公开(公告)号：EP0787029A1

公开(公告)日：1997-08-06

申请号：EP95934714.0

申请日：1995-10-20

申请人： CENTRAL RESEARCH LABORATORIES LIMITED

发明人： SHAW, John, Edward, Andrew ,  SIMPSON, Richard, Iain ,  BULL, Adrian, James ,  SIMPER, Adrian, Mark ,  HOLMES, Robert, George, Godfrey

IPC分类号： G01N1 ,  B01D11 ,  B01D61 ,  B01F13 ,  B01J19 ,  G01N25 ,  G01N27 ,  G01N30 ,  G01N37

CPC分类号： G01N1/4005 ,  B01D11/0403 ,  B01D11/0407 ,  B01D11/0415 ,  B01D11/0419 ,  B01D11/0426 ,  B01D11/043 ,  B01D11/0453 ,  B01D11/0496 ,  B01D61/246 ,  B01D61/28 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00833 ,  B01J2219/00844 ,  B01J2219/00853 ,  B01J2219/00907 ,  B01J2219/00995 ,  G01N1/34 ,  G01N25/14 ,  G01N27/44743 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2001/4016

摘要： PCT No. PCT/GB95/02488 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Oct. 20, 1995 PCT Pub. No. WO96/12540 PCT Pub. Date May 2, 1996In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the liquids without mixing, a method and an apparatus are disclosed and have first and second flow paths carrying first and second immiscible fluids on opposite sides of a foraminous sheet. The height of the apertures in the sheet is not greater than 200 micrometers (measured perpendicular to the width of the sheet and to the direction of fluid flow), and a stable interface is formed between the fluids within each aperture with a significant amount of fluid flow immediately adjacent the interface. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the region without mixing. The width of the flow paths measured perpendicular to sheet lies between 10 and 500 micrometers. The walls of each aperture may be parallel or tapered.

公开(公告)号：EP1567269A1

公开(公告)日：2005-08-31

申请号：EP03789521.6

申请日：2003-11-27

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： SARRUT, Nicolas

IPC分类号： B01L3/00 ,  G01N27/26

CPC分类号： B01F13/0076 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00853 ,  B01J2219/00889 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2400/0415

摘要： The invention concerns a microfluidic device (1) comprising at least one micro-channel delimited by lower (2), lateral (4) and upper (5) walls and designed to contain at least one liquid (6) and at least one fluid (7) non-miscible with the liquid (6). The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The stabilizing means include at least one electrode (9) arranged on at least one part of a first wall of the micro-channel, over the entire length thereof and at least one counter-electrode (10) arranged over the entire length of the micro-channel, on at least one part of a second wall, arranged opposite the electrode. The electrode (9) and the counter-electrode (10) are preferably respectively arranged on the micro-channel lower (2) and upper (5) walls.